FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2145659311> ?p ?o ?g. }

• W2145659311 endingPage "31" @default.
• W2145659311 startingPage "24" @default.
• W2145659311 abstract "A newly developed single quad mass spectrometry (MS) detector was coupled to a ultra-high performance liquid chromatography (UPLC) system and implemented in the routine quality control (QC) and impurity analysis of four therapeutic peptides, namely bleomycin sulfate, tyrothricin, vancomycin HCl and bacitracin, which were selected given their multi-component drug nature and their closely structurally related impurity profiles. The QC and impurity profiling results obtained using the ultra-high performance liquid chromatography ultraviolet/mass spectrometry (UPLC-UV/MS) detection system were analyzed against the results obtained using traditional high performance liquid chromatography-ultraviolet detection (HPLC-UV) methods derived from pharmacopoeial methods. In general, the used stationary phases of sub-2 µm particle (UPLC) technology resulted in lower limits of detection and higher resolution separations, which resulted in more detected impurities and shorter overall run times contrasting the traditional HPLC columns. Moreover, online coupling with a single quad MS detector allowed direct peak identification of the main compounds as well as small impurities, hereby increasing the information content without the need of reference standards." @default.
• W2145659311 created "2016-06-24" @default.
• W2145659311 creator A5015528105 @default.
• W2145659311 creator A5017615853 @default.
• W2145659311 creator A5046606266 @default.
• W2145659311 creator A5089956255 @default.
• W2145659311 date "2016-02-01" @default.
• W2145659311 modified "2023-10-17" @default.
• W2145659311 title "Implementation of a single quad MS detector in routine QC analysis of peptide drugs" @default.
• W2145659311 cites W1966144393 @default.
• W2145659311 cites W1970012021 @default.
• W2145659311 cites W1975558168 @default.
• W2145659311 cites W1979311824 @default.
• W2145659311 cites W1994709737 @default.
• W2145659311 cites W2003484869 @default.
• W2145659311 cites W2003649314 @default.
• W2145659311 cites W2008277785 @default.
• W2145659311 cites W2020844936 @default.
• W2145659311 cites W2023096047 @default.
• W2145659311 cites W2037837681 @default.
• W2145659311 cites W2039537250 @default.
• W2145659311 cites W2049631254 @default.
• W2145659311 cites W2053936196 @default.
• W2145659311 cites W2056495534 @default.
• W2145659311 cites W2058313010 @default.
• W2145659311 cites W2082631318 @default.
• W2145659311 cites W2083531531 @default.
• W2145659311 cites W2097368093 @default.
• W2145659311 cites W2097463865 @default.
• W2145659311 cites W2149424807 @default.
• W2145659311 cites W2156510510 @default.
• W2145659311 cites W2164036543 @default.
• W2145659311 cites W2318857954 @default.
• W2145659311 cites W2332883784 @default.
• W2145659311 cites W4211236956 @default.
• W2145659311 doi "https://doi.org/10.1016/j.jpha.2015.09.002" @default.
• W2145659311 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5762454" @default.
• W2145659311 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29403959" @default.
• W2145659311 hasPublicationYear "2016" @default.
• W2145659311 type Work @default.
• W2145659311 sameAs 2145659311 @default.
• W2145659311 citedByCount "14" @default.
• W2145659311 countsByYear W21456593112016 @default.
• W2145659311 countsByYear W21456593112017 @default.
• W2145659311 countsByYear W21456593112018 @default.
• W2145659311 countsByYear W21456593112020 @default.
• W2145659311 countsByYear W21456593112021 @default.
• W2145659311 countsByYear W21456593112022 @default.
• W2145659311 crossrefType "journal-article" @default.
• W2145659311 hasAuthorship W2145659311A5015528105 @default.
• W2145659311 hasAuthorship W2145659311A5017615853 @default.
• W2145659311 hasAuthorship W2145659311A5046606266 @default.
• W2145659311 hasAuthorship W2145659311A5089956255 @default.
• W2145659311 hasBestOaLocation W21456593111 @default.
• W2145659311 hasConcept C110084920 @default.
• W2145659311 hasConcept C113196181 @default.
• W2145659311 hasConcept C119128265 @default.
• W2145659311 hasConcept C120665830 @default.
• W2145659311 hasConcept C121332964 @default.
• W2145659311 hasConcept C145148216 @default.
• W2145659311 hasConcept C162356407 @default.
• W2145659311 hasConcept C16291436 @default.
• W2145659311 hasConcept C178790620 @default.
• W2145659311 hasConcept C179998833 @default.
• W2145659311 hasConcept C185592680 @default.
• W2145659311 hasConcept C198291218 @default.
• W2145659311 hasConcept C2776798109 @default.
• W2145659311 hasConcept C43617362 @default.
• W2145659311 hasConcept C49040817 @default.
• W2145659311 hasConcept C71987851 @default.
• W2145659311 hasConcept C94915269 @default.
• W2145659311 hasConceptScore W2145659311C110084920 @default.
• W2145659311 hasConceptScore W2145659311C113196181 @default.
• W2145659311 hasConceptScore W2145659311C119128265 @default.
• W2145659311 hasConceptScore W2145659311C120665830 @default.
• W2145659311 hasConceptScore W2145659311C121332964 @default.
• W2145659311 hasConceptScore W2145659311C145148216 @default.
• W2145659311 hasConceptScore W2145659311C162356407 @default.
• W2145659311 hasConceptScore W2145659311C16291436 @default.
• W2145659311 hasConceptScore W2145659311C178790620 @default.
• W2145659311 hasConceptScore W2145659311C179998833 @default.
• W2145659311 hasConceptScore W2145659311C185592680 @default.
• W2145659311 hasConceptScore W2145659311C198291218 @default.
• W2145659311 hasConceptScore W2145659311C2776798109 @default.
• W2145659311 hasConceptScore W2145659311C43617362 @default.
• W2145659311 hasConceptScore W2145659311C49040817 @default.
• W2145659311 hasConceptScore W2145659311C71987851 @default.
• W2145659311 hasConceptScore W2145659311C94915269 @default.
• W2145659311 hasIssue "1" @default.
• W2145659311 hasLocation W21456593111 @default.
• W2145659311 hasLocation W21456593112 @default.
• W2145659311 hasLocation W21456593113 @default.
• W2145659311 hasLocation W21456593114 @default.
• W2145659311 hasLocation W21456593115 @default.
• W2145659311 hasLocation W21456593116 @default.
• W2145659311 hasOpenAccess W2145659311 @default.
• W2145659311 hasPrimaryLocation W21456593111 @default.
• W2145659311 hasRelatedWork W2059628166 @default.

• next