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- W2145700788 abstract "12 patients with chronic staphylococcal osteomyelitis were treated with cloxacillin (6 patients) and dicloxacillin (6 patients) in a prospective, comparative study. The drugs were given perorally in the dose 1 g every 4th hour and serum concentrations were followed. 0.5, 1 and 2 hours after administration the serum level of dicloxacillin was about double that of cloxacillin. The lowest serum level of dicloxacillin at the time of administration of the drugs was nearly 3 times as high as the level of cloxacillin. An evaluation of clinical benefit and side-effects revealed no differences between the drugs. The prolonged serum level of dicloxacillin may permit a longer interval between doses than the administration of cloxacillin." @default.
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- W2145700788 date "1975-03-01" @default.
- W2145700788 modified "2023-09-26" @default.
- W2145700788 title "Treatment of Chronic Staphylococcal Osteomyelitis with Cloxacillin and Dicloxacillin—a Comparative Study in 12 Patients" @default.
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- W2145700788 doi "https://doi.org/10.3109/inf.1975.7.issue-1.10" @default.
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