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• W2145706089 abstract "Here we describe the development of a rapid and facile method for the colorimetric detection of penicillin antibiotics, including penicillin G, penicillin V, nafcillin, oxacillin, cloxacillin and dicloxacillin, using hybrid magnetic nanoparticle clusters (HMNCs) and penicillin class-selective, antibody-functionalized platinum nanoparticles (Ab-Pt). Amine-functionalized HMNCs were used to chemically capture antibiotics from sample solution through the formation of amide bonds between amine groups of HMNCs and carboxyl groups of the antibiotics. Ab-Pt was then allowed to bind to antibiotic–HMNC complexes, after which the resulting Pt–antibiotic–HMNCs were added to a 3,3′,5,5′-tetramethylbenzidine (TMB) solution. The color change caused by platinum nanoparticle-mediated oxidation of TMB enabled antibiotics to be identified with the naked eye and quantified by measuring light absorption. The use of the penicillin class-selective antibody allowed the simultaneous detection of penicillin class antibiotics, thereby reducing the cost, time, and effort associated with prescreening antibiotic residues in sample specimens." @default.
• W2145706089 created "2016-06-24" @default.
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• W2145706089 date "2015-01-01" @default.
• W2145706089 modified "2023-10-16" @default.
• W2145706089 title "Colorimetric detection of penicillin antibiotic residues in pork using hybrid magnetic nanoparticles and penicillin class-selective, antibody-functionalized platinum nanoparticles" @default.
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• W2145706089 doi "https://doi.org/10.1039/c5ay01590a" @default.
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