Matches in SemOpenAlex for { <https://semopenalex.org/work/W2145706987> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2145706987 endingPage "985" @default.
- W2145706987 startingPage "983" @default.
- W2145706987 abstract "A histochemical and morphometric study was performed on sequential bone marrow biopsies in 65 patients with idiopathic (primary) myelofibrosis (IMF) to quantify the resident-mature CD68+ macrophages and a peculiar, so-called activated subpopulation. Statistical analysis revealed no significant correlations between number of macrophages, density of argyrophilic fibers and degree of myeloid metaplasia. Our results are reflecting in vitro findings on cytokine release, macrophage activation and their complex functional associations with myelofibrotic matrix formation. Macrophage growth is assumed to be related to a number of putative pathomechanisms including abnormal (upregulated) cytokine expression (PDGF, TGF-beta, IL-1), enhancement and activation by CSF-1 (M-CSF) and possibly also phagocytic stimulation. The latter feature may be triggered by increased degradation of senescent megakaryocytes, frequently occurring as endstages of growth factors-releasing fibrogenetic megakaryopoiesis." @default.
- W2145706987 created "2016-06-24" @default.
- W2145706987 creator A5036871832 @default.
- W2145706987 creator A5056500119 @default.
- W2145706987 creator A5062759775 @default.
- W2145706987 date "1999-11-01" @default.
- W2145706987 modified "2023-09-26" @default.
- W2145706987 title "Resident bone marrow macrophages in idiopathic (primary) myelofibrosis (IMF): a histochemical and morphometric study on sequential trephine biopsies" @default.
- W2145706987 cites W1546217975 @default.
- W2145706987 cites W1963606224 @default.
- W2145706987 cites W1982170008 @default.
- W2145706987 cites W2037069604 @default.
- W2145706987 cites W2038023702 @default.
- W2145706987 cites W2045006939 @default.
- W2145706987 cites W2045427431 @default.
- W2145706987 cites W2047775152 @default.
- W2145706987 cites W2087890016 @default.
- W2145706987 cites W2150656708 @default.
- W2145706987 cites W4250581777 @default.
- W2145706987 cites W8638124 @default.
- W2145706987 doi "https://doi.org/10.1016/s0145-2126(99)00120-4" @default.
- W2145706987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10576501" @default.
- W2145706987 hasPublicationYear "1999" @default.
- W2145706987 type Work @default.
- W2145706987 sameAs 2145706987 @default.
- W2145706987 citedByCount "11" @default.
- W2145706987 countsByYear W21457069872014 @default.
- W2145706987 countsByYear W21457069872016 @default.
- W2145706987 countsByYear W21457069872018 @default.
- W2145706987 countsByYear W21457069872019 @default.
- W2145706987 countsByYear W21457069872020 @default.
- W2145706987 countsByYear W21457069872021 @default.
- W2145706987 crossrefType "journal-article" @default.
- W2145706987 hasAuthorship W2145706987A5036871832 @default.
- W2145706987 hasAuthorship W2145706987A5056500119 @default.
- W2145706987 hasAuthorship W2145706987A5062759775 @default.
- W2145706987 hasConcept C142724271 @default.
- W2145706987 hasConcept C202751555 @default.
- W2145706987 hasConcept C203014093 @default.
- W2145706987 hasConcept C204232928 @default.
- W2145706987 hasConcept C2776460901 @default.
- W2145706987 hasConcept C2778690821 @default.
- W2145706987 hasConcept C2779244956 @default.
- W2145706987 hasConcept C2779282312 @default.
- W2145706987 hasConcept C2779357193 @default.
- W2145706987 hasConcept C2780007613 @default.
- W2145706987 hasConcept C2780076729 @default.
- W2145706987 hasConcept C50442881 @default.
- W2145706987 hasConcept C55493867 @default.
- W2145706987 hasConcept C71924100 @default.
- W2145706987 hasConcept C86803240 @default.
- W2145706987 hasConceptScore W2145706987C142724271 @default.
- W2145706987 hasConceptScore W2145706987C202751555 @default.
- W2145706987 hasConceptScore W2145706987C203014093 @default.
- W2145706987 hasConceptScore W2145706987C204232928 @default.
- W2145706987 hasConceptScore W2145706987C2776460901 @default.
- W2145706987 hasConceptScore W2145706987C2778690821 @default.
- W2145706987 hasConceptScore W2145706987C2779244956 @default.
- W2145706987 hasConceptScore W2145706987C2779282312 @default.
- W2145706987 hasConceptScore W2145706987C2779357193 @default.
- W2145706987 hasConceptScore W2145706987C2780007613 @default.
- W2145706987 hasConceptScore W2145706987C2780076729 @default.
- W2145706987 hasConceptScore W2145706987C50442881 @default.
- W2145706987 hasConceptScore W2145706987C55493867 @default.
- W2145706987 hasConceptScore W2145706987C71924100 @default.
- W2145706987 hasConceptScore W2145706987C86803240 @default.
- W2145706987 hasIssue "11" @default.
- W2145706987 hasLocation W21457069871 @default.
- W2145706987 hasLocation W21457069872 @default.
- W2145706987 hasOpenAccess W2145706987 @default.
- W2145706987 hasPrimaryLocation W21457069871 @default.
- W2145706987 hasRelatedWork W1986759275 @default.
- W2145706987 hasRelatedWork W2000531137 @default.
- W2145706987 hasRelatedWork W2004172023 @default.
- W2145706987 hasRelatedWork W204834199 @default.
- W2145706987 hasRelatedWork W2067887730 @default.
- W2145706987 hasRelatedWork W2146376077 @default.
- W2145706987 hasRelatedWork W2168769539 @default.
- W2145706987 hasRelatedWork W2230366006 @default.
- W2145706987 hasRelatedWork W4235715404 @default.
- W2145706987 hasRelatedWork W4243804275 @default.
- W2145706987 hasVolume "23" @default.
- W2145706987 isParatext "false" @default.
- W2145706987 isRetracted "false" @default.
- W2145706987 magId "2145706987" @default.
- W2145706987 workType "article" @default.