FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2145757629> ?p ?o ?g. }

• W2145757629 abstract "The advance of high-throughput sequencing has made it possible to obtain new transcriptomes and study splicing mechanisms in non-model organisms. In these studies, there is often a need to investigate the transcriptomes of two related organisms at the same time in order to find the similarities and differences between them. The traditional approach to address this problem is to perform de novo transcriptome assemblies to obtain predicted transcripts for these organisms independently and then employ similarity comparison algorithms to study them.Instead of obtaining predicted transcripts for these organisms separately from the intermediate de Bruijn graph structures employed by de novo transcriptome assembly algorithms, we develop an algorithm to allow direct comparisons between paths in two de Bruijn graphs by first enumerating short paths in both graphs, and iteratively extending paths in one graph that have high similarity to paths in the other graph to obtain longer corresponding paths between the two graphs. These paths represent predicted transcripts that are present in both organisms.Our approach generalizes the pairwise sequence alignment problem to allow the input to be non-linear structures, and provides a heuristic to reliably recover similar paths from the two structures. Our algorithm allows detailed investigation of the similarities and differences in alternative splicing between the two organisms at both the sequence and structure levels, even in the absence of reference transcriptomes or a closely related model organism." @default.
• W2145757629 created "2016-06-24" @default.
• W2145757629 creator A5039599341 @default.
• W2145757629 creator A5050838787 @default.
• W2145757629 creator A5087258523 @default.
• W2145757629 date "2015-11-10" @default.
• W2145757629 modified "2023-10-10" @default.
• W2145757629 title "Heuristic pairwise alignment of de Bruijn graphs to facilitate simultaneous transcript discovery in related organisms from RNA-Seq data" @default.
• W2145757629 cites W1493192698 @default.
• W2145757629 cites W2022910024 @default.
• W2145757629 cites W2035111432 @default.
• W2145757629 cites W2055043387 @default.
• W2145757629 cites W2096525273 @default.
• W2145757629 cites W2106678197 @default.
• W2145757629 cites W2110392562 @default.
• W2145757629 cites W2112491476 @default.
• W2145757629 cites W2112888168 @default.
• W2145757629 cites W2118737448 @default.
• W2145757629 cites W2126419817 @default.
• W2145757629 cites W2141458291 @default.
• W2145757629 cites W2142749416 @default.
• W2145757629 cites W2151017710 @default.
• W2145757629 cites W2155201678 @default.
• W2145757629 cites W2156841387 @default.
• W2145757629 cites W2160969485 @default.
• W2145757629 cites W2161546116 @default.
• W2145757629 cites W4231041617 @default.
• W2145757629 doi "https://doi.org/10.1186/1471-2164-16-s11-s5" @default.
• W2145757629 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4652555" @default.
• W2145757629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26576690" @default.
• W2145757629 hasPublicationYear "2015" @default.
• W2145757629 type Work @default.
• W2145757629 sameAs 2145757629 @default.
• W2145757629 citedByCount "4" @default.
• W2145757629 countsByYear W21457576292018 @default.
• W2145757629 countsByYear W21457576292019 @default.
• W2145757629 countsByYear W21457576292021 @default.
• W2145757629 crossrefType "journal-article" @default.
• W2145757629 hasAuthorship W2145757629A5039599341 @default.
• W2145757629 hasAuthorship W2145757629A5050838787 @default.
• W2145757629 hasAuthorship W2145757629A5087258523 @default.
• W2145757629 hasBestOaLocation W21457576291 @default.
• W2145757629 hasConcept C104317684 @default.
• W2145757629 hasConcept C107397762 @default.
• W2145757629 hasConcept C114614502 @default.
• W2145757629 hasConcept C150194340 @default.
• W2145757629 hasConcept C154945302 @default.
• W2145757629 hasConcept C162317418 @default.
• W2145757629 hasConcept C170320093 @default.
• W2145757629 hasConcept C173801870 @default.
• W2145757629 hasConcept C184898388 @default.
• W2145757629 hasConcept C20218877 @default.
• W2145757629 hasConcept C33923547 @default.
• W2145757629 hasConcept C41008148 @default.
• W2145757629 hasConcept C47124935 @default.
• W2145757629 hasConcept C50489715 @default.
• W2145757629 hasConcept C54355233 @default.
• W2145757629 hasConcept C54458228 @default.
• W2145757629 hasConcept C67705224 @default.
• W2145757629 hasConcept C70721500 @default.
• W2145757629 hasConcept C86803240 @default.
• W2145757629 hasConceptScore W2145757629C104317684 @default.
• W2145757629 hasConceptScore W2145757629C107397762 @default.
• W2145757629 hasConceptScore W2145757629C114614502 @default.
• W2145757629 hasConceptScore W2145757629C150194340 @default.
• W2145757629 hasConceptScore W2145757629C154945302 @default.
• W2145757629 hasConceptScore W2145757629C162317418 @default.
• W2145757629 hasConceptScore W2145757629C170320093 @default.
• W2145757629 hasConceptScore W2145757629C173801870 @default.
• W2145757629 hasConceptScore W2145757629C184898388 @default.
• W2145757629 hasConceptScore W2145757629C20218877 @default.
• W2145757629 hasConceptScore W2145757629C33923547 @default.
• W2145757629 hasConceptScore W2145757629C41008148 @default.
• W2145757629 hasConceptScore W2145757629C47124935 @default.
• W2145757629 hasConceptScore W2145757629C50489715 @default.
• W2145757629 hasConceptScore W2145757629C54355233 @default.
• W2145757629 hasConceptScore W2145757629C54458228 @default.
• W2145757629 hasConceptScore W2145757629C67705224 @default.
• W2145757629 hasConceptScore W2145757629C70721500 @default.
• W2145757629 hasConceptScore W2145757629C86803240 @default.
• W2145757629 hasIssue "S11" @default.
• W2145757629 hasLocation W21457576291 @default.
• W2145757629 hasLocation W21457576292 @default.
• W2145757629 hasLocation W21457576293 @default.
• W2145757629 hasLocation W21457576294 @default.
• W2145757629 hasOpenAccess W2145757629 @default.
• W2145757629 hasPrimaryLocation W21457576291 @default.
• W2145757629 hasRelatedWork W2049364822 @default.
• W2145757629 hasRelatedWork W2099738370 @default.
• W2145757629 hasRelatedWork W2145757629 @default.
• W2145757629 hasRelatedWork W2186661753 @default.
• W2145757629 hasRelatedWork W2268123450 @default.
• W2145757629 hasRelatedWork W2396424000 @default.
• W2145757629 hasRelatedWork W2753066540 @default.
• W2145757629 hasRelatedWork W2926358864 @default.
• W2145757629 hasRelatedWork W3157557088 @default.
• W2145757629 hasRelatedWork W4206729893 @default.
• W2145757629 hasVolume "16" @default.
• W2145757629 isParatext "false" @default.
• W2145757629 isRetracted "false" @default.

• next