FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2145768809> ?p ?o ?g. }

• W2145768809 endingPage "84" @default.
• W2145768809 startingPage "80" @default.
• W2145768809 abstract "The perifornical (PF) region of the posterior hypothalamus plays an important role in the regulation of sleep–wake states and motor activity. Disinhibition of PF neurons by the GABAA receptor antagonist, bicuculline, has been used to study the mechanisms of wake- and motor activity-promoting effects that emanate from the PF region. Bicuculline activates PF neurons, including the orexin-containing cells that have major excitatory projections to brainstem noradrenergic and serotonergic neurons. Since premotor aminergic neurons are an important source of motoneuronal activation, we hypothesized that they mediate the excitation of motoneurons that results from disinhibition of PF neurons with bicuculline. In urethane-anesthetized, paralyzed and artificially ventilated rats, we found that PF bicuculline injections (1 mM, 20 nl) made after combined microinjections into the hypoglossal (XII) nucleus of α1-adrenergic and serotonergic receptor antagonists (prazosin and methysergide) increased XII nerve activity by 80 ± 16% (SE) of the control activity level. Thus, activation of XII motoneurons originating in the hypothalamic PF region was not abolished despite effective elimination by the aminergic antagonists of the endogenous noradrenergic and serotonergic excitatory drives to XII motoneurons and abolition of XII motoneuronal activation by exogenous serotonin or phenylephrine. These results show that a major component of XII motoneuronal activation originating in the posterior hypothalamus is mediated by pathways other than the noradrenergic and serotonergic projections to motoneurons." @default.
• W2145768809 created "2016-06-24" @default.
• W2145768809 creator A5012638027 @default.
• W2145768809 creator A5087555682 @default.
• W2145768809 creator A5090118332 @default.
• W2145768809 date "2009-09-01" @default.
• W2145768809 modified "2023-09-26" @default.
• W2145768809 title "Antagonism of α1-adrenergic and serotonergic receptors in the hypoglossal motor nucleus does not prevent motoneuronal activation elicited from the posterior hypothalamus" @default.
• W2145768809 cites W1596635370 @default.
• W2145768809 cites W1627229807 @default.
• W2145768809 cites W1942962897 @default.
• W2145768809 cites W1969970580 @default.
• W2145768809 cites W1977037306 @default.
• W2145768809 cites W1995433511 @default.
• W2145768809 cites W2013655437 @default.
• W2145768809 cites W2020663186 @default.
• W2145768809 cites W2021318456 @default.
• W2145768809 cites W2024524548 @default.
• W2145768809 cites W2028121897 @default.
• W2145768809 cites W2030779345 @default.
• W2145768809 cites W2035662131 @default.
• W2145768809 cites W2046019168 @default.
• W2145768809 cites W2048846730 @default.
• W2145768809 cites W2049813113 @default.
• W2145768809 cites W2072154498 @default.
• W2145768809 cites W2082790052 @default.
• W2145768809 cites W2083550321 @default.
• W2145768809 cites W2083595422 @default.
• W2145768809 cites W2085712847 @default.
• W2145768809 cites W2093069882 @default.
• W2145768809 cites W2100743305 @default.
• W2145768809 cites W2102884007 @default.
• W2145768809 cites W2128411903 @default.
• W2145768809 cites W2130513715 @default.
• W2145768809 cites W2148431641 @default.
• W2145768809 cites W2152513421 @default.
• W2145768809 cites W2161786832 @default.
• W2145768809 cites W2317902632 @default.
• W2145768809 doi "https://doi.org/10.1016/j.neulet.2009.06.083" @default.
• W2145768809 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2734450" @default.
• W2145768809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19573578" @default.
• W2145768809 hasPublicationYear "2009" @default.
• W2145768809 type Work @default.
• W2145768809 sameAs 2145768809 @default.
• W2145768809 citedByCount "8" @default.
• W2145768809 countsByYear W21457688092013 @default.
• W2145768809 countsByYear W21457688092014 @default.
• W2145768809 countsByYear W21457688092015 @default.
• W2145768809 countsByYear W21457688092016 @default.
• W2145768809 countsByYear W21457688092019 @default.
• W2145768809 crossrefType "journal-article" @default.
• W2145768809 hasAuthorship W2145768809A5012638027 @default.
• W2145768809 hasAuthorship W2145768809A5087555682 @default.
• W2145768809 hasAuthorship W2145768809A5090118332 @default.
• W2145768809 hasBestOaLocation W21457688092 @default.
• W2145768809 hasConcept C126322002 @default.
• W2145768809 hasConcept C134018914 @default.
• W2145768809 hasConcept C169760540 @default.
• W2145768809 hasConcept C170493617 @default.
• W2145768809 hasConcept C185592680 @default.
• W2145768809 hasConcept C2775864247 @default.
• W2145768809 hasConcept C2776885963 @default.
• W2145768809 hasConcept C2777003273 @default.
• W2145768809 hasConcept C2780648677 @default.
• W2145768809 hasConcept C2780714764 @default.
• W2145768809 hasConcept C2780763569 @default.
• W2145768809 hasConcept C2781005078 @default.
• W2145768809 hasConcept C37000724 @default.
• W2145768809 hasConcept C551621295 @default.
• W2145768809 hasConcept C71924100 @default.
• W2145768809 hasConcept C79636183 @default.
• W2145768809 hasConcept C86803240 @default.
• W2145768809 hasConceptScore W2145768809C126322002 @default.
• W2145768809 hasConceptScore W2145768809C134018914 @default.
• W2145768809 hasConceptScore W2145768809C169760540 @default.
• W2145768809 hasConceptScore W2145768809C170493617 @default.
• W2145768809 hasConceptScore W2145768809C185592680 @default.
• W2145768809 hasConceptScore W2145768809C2775864247 @default.
• W2145768809 hasConceptScore W2145768809C2776885963 @default.
• W2145768809 hasConceptScore W2145768809C2777003273 @default.
• W2145768809 hasConceptScore W2145768809C2780648677 @default.
• W2145768809 hasConceptScore W2145768809C2780714764 @default.
• W2145768809 hasConceptScore W2145768809C2780763569 @default.
• W2145768809 hasConceptScore W2145768809C2781005078 @default.
• W2145768809 hasConceptScore W2145768809C37000724 @default.
• W2145768809 hasConceptScore W2145768809C551621295 @default.
• W2145768809 hasConceptScore W2145768809C71924100 @default.
• W2145768809 hasConceptScore W2145768809C79636183 @default.
• W2145768809 hasConceptScore W2145768809C86803240 @default.
• W2145768809 hasIssue "1" @default.
• W2145768809 hasLocation W21457688091 @default.
• W2145768809 hasLocation W21457688092 @default.
• W2145768809 hasLocation W21457688093 @default.
• W2145768809 hasLocation W21457688094 @default.
• W2145768809 hasOpenAccess W2145768809 @default.
• W2145768809 hasPrimaryLocation W21457688091 @default.
• W2145768809 hasRelatedWork W1965743830 @default.
• W2145768809 hasRelatedWork W1983321239 @default.

• next