FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2145858946> ?p ?o ?g. }

• W2145858946 endingPage "378" @default.
• W2145858946 startingPage "373" @default.
• W2145858946 abstract "Pregnant Wistar rats were used to investigate the anti-implantation effect of cyclooxygenase (COX) inhibitors, indomethacin (nonselective COX-1/COX-2 inhibitor) and celecoxib (specific COX-2 inhibitor). Indomethacin at doses of 2.5 and 5 mg/kg/day and celecoxib at doses of 40, 80, and 160 mg/kg/day were orally administered once daily to each group (n = 8) on Days 3–5 of pregnancy (Day 1 = sperm detection). Indomethacin and celecoxib at anti-implantation dosages were further investigated for the effects on changes in endometrial vascular permeability in pregnant rats and uterine decidualization in pseudopregnant rats. The results demonstrated that indomethacin at a dose of 5 mg/kg/day as well as celecoxib at doses of 80 and 160 mg/kg/day could significantly reduce the proportion of pregnant rats. At the anti-implantation dosages, they exhibited no significant effect on proportion of rats with blue dye sites in the endometrial vascular permeability study, but they could significantly reduce the uterine decidualization. From these findings, the anti-implantation effect of the two COX inhibitors may principally be from decidualization defects, and COX inhibitors should, therefore, be used with caution in childbearing age women. On the other hand, specific COX-2 inhibitors with their good gastric safety profile may have a potential role in nonhormonal postcoital contraception." @default.
• W2145858946 created "2016-06-24" @default.
• W2145858946 creator A5020268334 @default.
• W2145858946 creator A5061372978 @default.
• W2145858946 date "2002-05-01" @default.
• W2145858946 modified "2023-10-15" @default.
• W2145858946 title "Anti-implantation effects of indomethacin and celecoxib in rats" @default.
• W2145858946 cites W1973074971 @default.
• W2145858946 cites W1973227153 @default.
• W2145858946 cites W1974450761 @default.
• W2145858946 cites W1990030459 @default.
• W2145858946 cites W2000325283 @default.
• W2145858946 cites W2003594973 @default.
• W2145858946 cites W2012501667 @default.
• W2145858946 cites W2017051199 @default.
• W2145858946 cites W2033498682 @default.
• W2145858946 cites W2034475021 @default.
• W2145858946 cites W2045713138 @default.
• W2145858946 cites W2049987133 @default.
• W2145858946 cites W2065888285 @default.
• W2145858946 cites W2072323299 @default.
• W2145858946 cites W2080969081 @default.
• W2145858946 cites W2085052924 @default.
• W2145858946 cites W2094761607 @default.
• W2145858946 cites W2097312992 @default.
• W2145858946 cites W2105931722 @default.
• W2145858946 cites W2110802125 @default.
• W2145858946 cites W2121088837 @default.
• W2145858946 cites W2123513105 @default.
• W2145858946 cites W2125992451 @default.
• W2145858946 cites W2126520833 @default.
• W2145858946 cites W2154332465 @default.
• W2145858946 cites W2172295241 @default.
• W2145858946 cites W2212475839 @default.
• W2145858946 cites W4239127512 @default.
• W2145858946 cites W4247667425 @default.
• W2145858946 cites W4250237624 @default.
• W2145858946 cites W4252637982 @default.
• W2145858946 doi "https://doi.org/10.1016/s0010-7824(01)00322-5" @default.
• W2145858946 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12057792" @default.
• W2145858946 hasPublicationYear "2002" @default.
• W2145858946 type Work @default.
• W2145858946 sameAs 2145858946 @default.
• W2145858946 citedByCount "50" @default.
• W2145858946 countsByYear W21458589462012 @default.
• W2145858946 countsByYear W21458589462013 @default.
• W2145858946 countsByYear W21458589462014 @default.
• W2145858946 countsByYear W21458589462015 @default.
• W2145858946 countsByYear W21458589462016 @default.
• W2145858946 countsByYear W21458589462017 @default.
• W2145858946 countsByYear W21458589462018 @default.
• W2145858946 countsByYear W21458589462020 @default.
• W2145858946 countsByYear W21458589462021 @default.
• W2145858946 countsByYear W21458589462023 @default.
• W2145858946 crossrefType "journal-article" @default.
• W2145858946 hasAuthorship W2145858946A5020268334 @default.
• W2145858946 hasAuthorship W2145858946A5061372978 @default.
• W2145858946 hasConcept C126322002 @default.
• W2145858946 hasConcept C134018914 @default.
• W2145858946 hasConcept C162156334 @default.
• W2145858946 hasConcept C181199279 @default.
• W2145858946 hasConcept C2776467144 @default.
• W2145858946 hasConcept C2778227567 @default.
• W2145858946 hasConcept C2778316770 @default.
• W2145858946 hasConcept C2779066055 @default.
• W2145858946 hasConcept C2779234561 @default.
• W2145858946 hasConcept C2779689624 @default.
• W2145858946 hasConcept C54355233 @default.
• W2145858946 hasConcept C55493867 @default.
• W2145858946 hasConcept C71924100 @default.
• W2145858946 hasConcept C86803240 @default.
• W2145858946 hasConcept C98274493 @default.
• W2145858946 hasConceptScore W2145858946C126322002 @default.
• W2145858946 hasConceptScore W2145858946C134018914 @default.
• W2145858946 hasConceptScore W2145858946C162156334 @default.
• W2145858946 hasConceptScore W2145858946C181199279 @default.
• W2145858946 hasConceptScore W2145858946C2776467144 @default.
• W2145858946 hasConceptScore W2145858946C2778227567 @default.
• W2145858946 hasConceptScore W2145858946C2778316770 @default.
• W2145858946 hasConceptScore W2145858946C2779066055 @default.
• W2145858946 hasConceptScore W2145858946C2779234561 @default.
• W2145858946 hasConceptScore W2145858946C2779689624 @default.
• W2145858946 hasConceptScore W2145858946C54355233 @default.
• W2145858946 hasConceptScore W2145858946C55493867 @default.
• W2145858946 hasConceptScore W2145858946C71924100 @default.
• W2145858946 hasConceptScore W2145858946C86803240 @default.
• W2145858946 hasConceptScore W2145858946C98274493 @default.
• W2145858946 hasIssue "5" @default.
• W2145858946 hasLocation W21458589461 @default.
• W2145858946 hasLocation W21458589462 @default.
• W2145858946 hasOpenAccess W2145858946 @default.
• W2145858946 hasPrimaryLocation W21458589461 @default.
• W2145858946 hasRelatedWork W1593721960 @default.
• W2145858946 hasRelatedWork W1975601342 @default.
• W2145858946 hasRelatedWork W1976264663 @default.
• W2145858946 hasRelatedWork W1993421498 @default.
• W2145858946 hasRelatedWork W2041392926 @default.
• W2145858946 hasRelatedWork W2068791368 @default.

• next