FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2145890684> ?p ?o ?g. }

• W2145890684 endingPage "3636" @default.
• W2145890684 startingPage "3625" @default.
• W2145890684 abstract "To collect the ever-increasing yet scattered knowledge on metabolism, multiple pathway databases like the Kyoto Encyclopedia of Genes and Genomes have been created. A complete and accurate description of the metabolic network for human and other organisms is essential to foster new biological discoveries. Previous research has shown, however, that the level of agreement among pathway databases is surprisingly low. We investigated whether the lack of consensus among databases can be explained by an inaccurate representation of the knowledge described in scientific literature. As an example, we focus on the well-known tricarboxylic acid (TCA) cycle and evaluated the description of this pathway as found in a comprehensive selection of 10 human metabolic pathway databases. Remarkably, none of the descriptions given by these databases is entirely correct. Moreover, consensus exists on only 3 reactions. Mistakes in pathway databases might lead to the propagation of incorrect knowledge, misinterpretation of high-throughput molecular data, and poorly designed follow-up experiments. We provide an improved description of the TCA cycle via the community-curated database WikiPathways. We review various initiatives that aim to improve the description of the human metabolic network and discuss the importance of the active involvement of biological experts in these." @default.
• W2145890684 created "2016-06-24" @default.
• W2145890684 creator A5006687544 @default.
• W2145890684 creator A5027561354 @default.
• W2145890684 creator A5027726446 @default.
• W2145890684 creator A5040743356 @default.
• W2145890684 creator A5073421485 @default.
• W2145890684 date "2012-06-01" @default.
• W2145890684 modified "2023-10-18" @default.
• W2145890684 title "Improving the description of metabolic networks: the TCA cycle as example" @default.
• W2145890684 cites W135930319 @default.
• W2145890684 cites W1523008440 @default.
• W2145890684 cites W1533884306 @default.
• W2145890684 cites W1542309964 @default.
• W2145890684 cites W1561585380 @default.
• W2145890684 cites W1792666615 @default.
• W2145890684 cites W1849245709 @default.
• W2145890684 cites W1902776418 @default.
• W2145890684 cites W1965717705 @default.
• W2145890684 cites W1985512202 @default.
• W2145890684 cites W1985591441 @default.
• W2145890684 cites W1996736495 @default.
• W2145890684 cites W1998767819 @default.
• W2145890684 cites W1999351218 @default.
• W2145890684 cites W2010502047 @default.
• W2145890684 cites W2010707723 @default.
• W2145890684 cites W2019509361 @default.
• W2145890684 cites W2025623576 @default.
• W2145890684 cites W2028133290 @default.
• W2145890684 cites W2031050244 @default.
• W2145890684 cites W2047632644 @default.
• W2145890684 cites W2048649216 @default.
• W2145890684 cites W2050153048 @default.
• W2145890684 cites W2056365020 @default.
• W2145890684 cites W2057315336 @default.
• W2145890684 cites W2057545775 @default.
• W2145890684 cites W2059131422 @default.
• W2145890684 cites W2063377610 @default.
• W2145890684 cites W2065181342 @default.
• W2145890684 cites W2068380480 @default.
• W2145890684 cites W2072885613 @default.
• W2145890684 cites W2079151410 @default.
• W2145890684 cites W2079475368 @default.
• W2145890684 cites W2080461503 @default.
• W2145890684 cites W2081010896 @default.
• W2145890684 cites W2083437014 @default.
• W2145890684 cites W2085820361 @default.
• W2145890684 cites W2085945924 @default.
• W2145890684 cites W2090765646 @default.
• W2145890684 cites W2092152920 @default.
• W2145890684 cites W2098824895 @default.
• W2145890684 cites W2102899487 @default.
• W2145890684 cites W2103017472 @default.
• W2145890684 cites W2103950919 @default.
• W2145890684 cites W2104108767 @default.
• W2145890684 cites W2104754657 @default.
• W2145890684 cites W2108648814 @default.
• W2145890684 cites W2111905282 @default.
• W2145890684 cites W2117692326 @default.
• W2145890684 cites W2120793213 @default.
• W2145890684 cites W2133510724 @default.
• W2145890684 cites W2134394193 @default.
• W2145890684 cites W2149343603 @default.
• W2145890684 cites W2150076905 @default.
• W2145890684 cites W2158440231 @default.
• W2145890684 cites W2160648343 @default.
• W2145890684 cites W2161214077 @default.
• W2145890684 cites W2162790428 @default.
• W2145890684 cites W2170940180 @default.
• W2145890684 cites W29260242 @default.
• W2145890684 cites W87258604 @default.
• W2145890684 doi "https://doi.org/10.1096/fj.11-203091" @default.
• W2145890684 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22661004" @default.
• W2145890684 hasPublicationYear "2012" @default.
• W2145890684 type Work @default.
• W2145890684 sameAs 2145890684 @default.
• W2145890684 citedByCount "23" @default.
• W2145890684 countsByYear W21458906842013 @default.
• W2145890684 countsByYear W21458906842014 @default.
• W2145890684 countsByYear W21458906842015 @default.
• W2145890684 countsByYear W21458906842016 @default.
• W2145890684 countsByYear W21458906842019 @default.
• W2145890684 countsByYear W21458906842020 @default.
• W2145890684 countsByYear W21458906842021 @default.
• W2145890684 countsByYear W21458906842022 @default.
• W2145890684 countsByYear W21458906842023 @default.
• W2145890684 crossrefType "journal-article" @default.
• W2145890684 hasAuthorship W2145890684A5006687544 @default.
• W2145890684 hasAuthorship W2145890684A5027561354 @default.
• W2145890684 hasAuthorship W2145890684A5027726446 @default.
• W2145890684 hasAuthorship W2145890684A5040743356 @default.
• W2145890684 hasAuthorship W2145890684A5073421485 @default.
• W2145890684 hasConcept C101810790 @default.
• W2145890684 hasConcept C104317684 @default.
• W2145890684 hasConcept C150194340 @default.
• W2145890684 hasConcept C152724338 @default.
• W2145890684 hasConcept C154945302 @default.
• W2145890684 hasConcept C162317418 @default.

• next