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- W2145983286 abstract "Introduction: Assessment of FeNO) provides a measure of Th2 airway inflammation that cannot be provided by other routinely asthma assessment tools. In fact, spirometry and asthma control tests (ACT) or questionnaires (ACQ) don9t inform about airway inflammation. Objective: To determine the ability of physicians to assess airway inflammation using standard clinical tools and assess how FeNO levels effect treatment decision making by asthma specialists. Methods: A total of 50 subjects ages 7-60 years with asthma were recruited at a asthma and allergy specialty practice. Patients underwent routine clinical assessment including spirometry and ACT testing. Physicians then clinically assessed airway inflammation as low, intermediate, high or unknown and determined a treatment plan. Subjects then underwent FeNO testing and the results were provided to the physicians who then had an opportunity to modify the asthma treatment plan. Results: Physician judgment on the level of airway inflammation was incorrect in 51.2% and correct in 48.8%. Of note, airway inflammation was low in 8 of 50 subjects in whom physicians assessed it as intermediate or high and was high in 9 of 50 subjects in whom physicians assessed it as low or intermediate. Importantly, treatment decisions were substantially altered in 40% of subjects following FeNO determination. Conclusions: Clinical assessments by asthma specialists were inadequate for assessing airway inflammation. These results have important effectiveness and cost implications for asthma management since FeNO determinations substantially impacted treatment decision making in 40% patients." @default.
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- W2145983286 date "2013-09-01" @default.
- W2145983286 modified "2023-09-26" @default.
- W2145983286 title "The impact of fractional exhaled nitric oxide (FeNO) measurement on treatment decision making in the specialist care of established asthma" @default.
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