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- W2145993565 abstract "Background: Leptospirosis is considered one of the most important emerging infectious diseases. Increase of storms and flooding has been associated to the Global warming. Although storm and hurricane hits Dominican Republic almost every year, an outbreak of Leptospirosis was not identified until the tropical storm Noel hit the Dominican Republic on October, 2007. The objective of the study is to describe the epidemiological and clinical characteristic of patients with leptospirosis in this outbreak. Methods: this is a descriptive, observational and cross-sectional study to determine the clinical and epidemiological characteristics of 60 patients admitted to the Robert Reid Cabral Children's Hospital with a suspicious diagnosis of leptospirosis. Results: Sixty patients were admitted with diagnostic of suspicious leptospirosis during November 15th to December 15th, 2007. Positive serological confirmations were in 22 patients (36.6%). Male were 68.3% and female 31.7%. Sixty three percent of patients were involved in flooding. Weil Syndrome was present in six (31.8%) patients and two of them died. The most frequent signs and symptoms were abdominal pain 11 (50.0%), headache 15 (68.2%); vomits 14 (63.0%), and jaundice 8 (36.0%) and conjunctivitis 4 (18.2%). There were 6 (27.3%) patients with acute renal failure (ARF), in which 50% required hemodialysis with 2 (3.3%) deaths. Thrombocytopenia was observed in 6 (27.3%) and albuminuria was present in 9 (40.9%). In 50% of patients with ARF thrombocytopenia (<100,000 mm) was present. Conclusion: This is the first leptospirosis outbreak that has been reported in country. An important risk factor was flooding secondary to tropical storm. It is important to mobilize health care team to surveillance directly to the areas affected by tropical storm to detected and give prophylaxis treatment." @default.
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- W2145993565 date "2008-12-01" @default.
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- W2145993565 title "Outbreak of Leptospirosis in Children After Tropical Storm in the Dominican Republic" @default.
- W2145993565 doi "https://doi.org/10.1016/j.ijid.2008.05.894" @default.
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