Matches in SemOpenAlex for { <https://semopenalex.org/work/W2145994037> ?p ?o ?g. }
- W2145994037 endingPage "3254" @default.
- W2145994037 startingPage "3244" @default.
- W2145994037 abstract "The genetic diversity of Borrelia burgdorferi sensu stricto, the agent of Lyme disease in North America, has consequences for the performance of serological diagnostic tests and disease severity. To investigate B. burgdorferi diversity in Canada, where Lyme disease is emerging, bacterial DNA in 309 infected adult Ixodes scapularis ticks collected in surveillance was characterized by multilocus sequence typing (MLST) and analysis of outer surface protein C gene (ospC) alleles. Six ticks carried Borrelia miyamotoi, and one tick carried the novel species Borrelia kurtenbachii. 142 ticks carried B. burgdorferi sequence types (STs) previously described from the United States. Fifty-eight ticks carried B. burgdorferi of 1 of 19 novel or undescribed STs, which were single-, double-, or triple-locus variants of STs first described in the United States. Clonal complexes with founder STs from the United States were identified. Seventeen ospC alleles were identified in 309 B. burgdorferi-infected ticks. Positive and negative associations in the occurrence of different alleles in the same tick supported a hypothesis of multiple-niche polymorphism for B. burgdorferi in North America. Geographic analysis of STs and ospC alleles were consistent with south-to-north dispersion of infected ticks from U.S. sources on migratory birds. These observations suggest that the genetic diversity of B. burgdorferi in eastern and central Canada corresponds to that in the United States, but there was evidence for founder events skewing the diversity in emerging tick populations. Further studies are needed to investigate the significance of these observations for the performance of diagnostic tests and clinical presentation of Lyme disease in Canada." @default.
- W2145994037 created "2016-06-24" @default.
- W2145994037 creator A5006259485 @default.
- W2145994037 creator A5008018976 @default.
- W2145994037 creator A5014816450 @default.
- W2145994037 creator A5048614585 @default.
- W2145994037 creator A5056967580 @default.
- W2145994037 creator A5068117269 @default.
- W2145994037 creator A5085181905 @default.
- W2145994037 creator A5086165449 @default.
- W2145994037 creator A5089866109 @default.
- W2145994037 date "2011-05-15" @default.
- W2145994037 modified "2023-10-14" @default.
- W2145994037 title "Investigation of Genotypes of Borrelia burgdorferi in Ixodes scapularis Ticks Collected during Surveillance in Canada" @default.
- W2145994037 cites W1655259452 @default.
- W2145994037 cites W1841184173 @default.
- W2145994037 cites W1999417916 @default.
- W2145994037 cites W2002151188 @default.
- W2145994037 cites W2002809595 @default.
- W2145994037 cites W2012244764 @default.
- W2145994037 cites W2045548110 @default.
- W2145994037 cites W2050092274 @default.
- W2145994037 cites W2050294315 @default.
- W2145994037 cites W2051188926 @default.
- W2145994037 cites W2096291738 @default.
- W2145994037 cites W2098448352 @default.
- W2145994037 cites W2098973334 @default.
- W2145994037 cites W2102801292 @default.
- W2145994037 cites W2103513093 @default.
- W2145994037 cites W2103546861 @default.
- W2145994037 cites W2105987593 @default.
- W2145994037 cites W2107621690 @default.
- W2145994037 cites W2117022997 @default.
- W2145994037 cites W2118153179 @default.
- W2145994037 cites W2121225700 @default.
- W2145994037 cites W2122003767 @default.
- W2145994037 cites W2122404765 @default.
- W2145994037 cites W2134728187 @default.
- W2145994037 cites W2136174053 @default.
- W2145994037 cites W2137106589 @default.
- W2145994037 cites W2141676247 @default.
- W2145994037 cites W2146396346 @default.
- W2145994037 cites W2146917428 @default.
- W2145994037 cites W2147636984 @default.
- W2145994037 cites W2149652290 @default.
- W2145994037 cites W2156255552 @default.
- W2145994037 cites W2161612644 @default.
- W2145994037 cites W2166361383 @default.
- W2145994037 cites W2181047597 @default.
- W2145994037 cites W4321429471 @default.
- W2145994037 doi "https://doi.org/10.1128/aem.02636-10" @default.
- W2145994037 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3126474" @default.
- W2145994037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21421790" @default.
- W2145994037 hasPublicationYear "2011" @default.
- W2145994037 type Work @default.
- W2145994037 sameAs 2145994037 @default.
- W2145994037 citedByCount "91" @default.
- W2145994037 countsByYear W21459940372012 @default.
- W2145994037 countsByYear W21459940372013 @default.
- W2145994037 countsByYear W21459940372014 @default.
- W2145994037 countsByYear W21459940372015 @default.
- W2145994037 countsByYear W21459940372016 @default.
- W2145994037 countsByYear W21459940372017 @default.
- W2145994037 countsByYear W21459940372018 @default.
- W2145994037 countsByYear W21459940372019 @default.
- W2145994037 countsByYear W21459940372020 @default.
- W2145994037 countsByYear W21459940372021 @default.
- W2145994037 countsByYear W21459940372022 @default.
- W2145994037 countsByYear W21459940372023 @default.
- W2145994037 crossrefType "journal-article" @default.
- W2145994037 hasAuthorship W2145994037A5006259485 @default.
- W2145994037 hasAuthorship W2145994037A5008018976 @default.
- W2145994037 hasAuthorship W2145994037A5014816450 @default.
- W2145994037 hasAuthorship W2145994037A5048614585 @default.
- W2145994037 hasAuthorship W2145994037A5056967580 @default.
- W2145994037 hasAuthorship W2145994037A5068117269 @default.
- W2145994037 hasAuthorship W2145994037A5085181905 @default.
- W2145994037 hasAuthorship W2145994037A5086165449 @default.
- W2145994037 hasAuthorship W2145994037A5089866109 @default.
- W2145994037 hasBestOaLocation W21459940371 @default.
- W2145994037 hasConcept C104317684 @default.
- W2145994037 hasConcept C135763542 @default.
- W2145994037 hasConcept C159047783 @default.
- W2145994037 hasConcept C159654299 @default.
- W2145994037 hasConcept C2776127032 @default.
- W2145994037 hasConcept C2776397665 @default.
- W2145994037 hasConcept C2777553296 @default.
- W2145994037 hasConcept C2779159148 @default.
- W2145994037 hasConcept C2779620486 @default.
- W2145994037 hasConcept C2780508971 @default.
- W2145994037 hasConcept C2781453105 @default.
- W2145994037 hasConcept C2908647359 @default.
- W2145994037 hasConcept C54355233 @default.
- W2145994037 hasConcept C71924100 @default.
- W2145994037 hasConcept C77434933 @default.
- W2145994037 hasConcept C81977670 @default.
- W2145994037 hasConcept C86803240 @default.
- W2145994037 hasConcept C99454951 @default.