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- W2146085288 abstract "Lymphedema is a chronic debilitating condition and curative treatment is yet to be found. Tissue engineering approach, which combines cellular components, scaffold, and molecular signals hold great potential in the treatment of secondary lymphedema with the advent of lymphatic graft to reconstruct damaged collecting lymphatic vessel. This review highlights the ideal characteristics of lymphatic graft, the limitation and challenges faced, and the approaches in developing tissue-engineered lymphatic graft.Literature on tissue engineering of lymphatic system and lymphatic tissue biology was reviewed.The prime challenge in the design and manufacturing of this graft is producing endothelialized conduit with intraluminal valves. Suitable scaffold material is needed to ensure stability and functionality of the construct. Endothelialization of the construct can be enhanced via biofunctionalization and nanotopography, which mimics extracellular matrix. Nanocomposite polymers with improved performance over existing biomaterials are likely to benefit the development of lymphatic graft.With the in-depth understanding of tissue engineering, nanotechnology, and improved knowledge on the biology of lymphatic regeneration, the aspiration to develop successful lymphatic graft is well achievable." @default.
- W2146085288 created "2016-06-24" @default.
- W2146085288 creator A5021230385 @default.
- W2146085288 creator A5027254078 @default.
- W2146085288 creator A5051672741 @default.
- W2146085288 creator A5081956660 @default.
- W2146085288 creator A5085574396 @default.
- W2146085288 creator A5089710103 @default.
- W2146085288 date "2014-12-01" @default.
- W2146085288 modified "2023-09-22" @default.
- W2146085288 title "Tissue-engineered lymphatic graft for the treatment of lymphedema" @default.
- W2146085288 cites W1527522386 @default.
- W2146085288 cites W1529577988 @default.
- W2146085288 cites W1640238077 @default.
- W2146085288 cites W1928716232 @default.
- W2146085288 cites W1970121528 @default.
- W2146085288 cites W1971693536 @default.
- W2146085288 cites W1973917593 @default.
- W2146085288 cites W1978912444 @default.
- W2146085288 cites W1979251800 @default.
- W2146085288 cites W1979818342 @default.
- W2146085288 cites W1981280006 @default.
- W2146085288 cites W1986288593 @default.
- W2146085288 cites W1988248351 @default.
- W2146085288 cites W1989050480 @default.
- W2146085288 cites W1992101966 @default.
- W2146085288 cites W1994864886 @default.
- W2146085288 cites W1995277841 @default.
- W2146085288 cites W1996527882 @default.
- W2146085288 cites W1996759453 @default.
- W2146085288 cites W1999122069 @default.
- W2146085288 cites W2001822903 @default.
- W2146085288 cites W2004900022 @default.
- W2146085288 cites W2005706292 @default.
- W2146085288 cites W2005846882 @default.
- W2146085288 cites W2013443224 @default.
- W2146085288 cites W2014792716 @default.
- W2146085288 cites W2017390700 @default.
- W2146085288 cites W2018279532 @default.
- W2146085288 cites W2023530067 @default.
- W2146085288 cites W2026385925 @default.
- W2146085288 cites W2027502681 @default.
- W2146085288 cites W2036662335 @default.
- W2146085288 cites W2038581980 @default.
- W2146085288 cites W2039326587 @default.
- W2146085288 cites W2043709708 @default.
- W2146085288 cites W2044177453 @default.
- W2146085288 cites W2045339683 @default.
- W2146085288 cites W2045663895 @default.
- W2146085288 cites W2046513138 @default.
- W2146085288 cites W2048246557 @default.
- W2146085288 cites W2048606411 @default.
- W2146085288 cites W2052862499 @default.
- W2146085288 cites W2058888942 @default.
- W2146085288 cites W2059108446 @default.
- W2146085288 cites W2067718143 @default.
- W2146085288 cites W2068581049 @default.
- W2146085288 cites W2069760873 @default.
- W2146085288 cites W2079024590 @default.
- W2146085288 cites W2084904400 @default.
- W2146085288 cites W2093622441 @default.
- W2146085288 cites W2096106665 @default.
- W2146085288 cites W2096201131 @default.
- W2146085288 cites W2097838494 @default.
- W2146085288 cites W2099126984 @default.
- W2146085288 cites W2099366913 @default.
- W2146085288 cites W2099743020 @default.
- W2146085288 cites W2100172627 @default.
- W2146085288 cites W2101848658 @default.
- W2146085288 cites W2105579911 @default.
- W2146085288 cites W2110862517 @default.
- W2146085288 cites W2113265524 @default.
- W2146085288 cites W2113461502 @default.
- W2146085288 cites W2114587721 @default.
- W2146085288 cites W2115374812 @default.
- W2146085288 cites W2116298485 @default.
- W2146085288 cites W2124566470 @default.
- W2146085288 cites W2132293422 @default.
- W2146085288 cites W2134774645 @default.
- W2146085288 cites W2135712089 @default.
- W2146085288 cites W2138469231 @default.
- W2146085288 cites W2140119911 @default.
- W2146085288 cites W2142739945 @default.
- W2146085288 cites W2146553975 @default.
- W2146085288 cites W2147153812 @default.
- W2146085288 cites W2147299114 @default.
- W2146085288 cites W2148852502 @default.
- W2146085288 cites W2151311370 @default.
- W2146085288 cites W2157180849 @default.
- W2146085288 cites W2158627817 @default.
- W2146085288 cites W2159331913 @default.
- W2146085288 cites W2161320063 @default.
- W2146085288 cites W2161715037 @default.
- W2146085288 cites W2162252600 @default.
- W2146085288 cites W2165316477 @default.
- W2146085288 cites W2166390740 @default.
- W2146085288 cites W2166573361 @default.
- W2146085288 cites W2167714604 @default.