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- W2146086412 abstract "In the development of the immune response, the dendritic cell subset of leukocytes plays a key role in enhnacing immunogenicity. Dendritic cells can pick up antigens in the tissues and move to lymphoid organs, through which T cells continually recirculate. It is proposed that dendritic cells at these sites express functions which have been identified in tissue culture models. These involve efficient binding to antigen-specific T lymphocytes, as well as the induction of the lymphokines and growth factor receptors required for immunity. The dendritic cell system, apparently under the control of cytokines, is a sentinel designed to signal T cells that a significant antigen burden is present, and to generate the activated T lymphoblasts that interact with many other cell types to bring about an immune response." @default.
- W2146086412 created "2016-06-24" @default.
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- W2146086412 date "1989-05-01" @default.
- W2146086412 modified "2023-10-06" @default.
- W2146086412 title "Immunogenicity: Role of dendritic cells" @default.
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- W2146086412 doi "https://doi.org/10.1002/bies.950100503" @default.
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