FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146122014> ?p ?o ?g. }

• W2146122014 abstract "Host responses against invading pathogens are basic physiological reactions of all living organisms. Since appearance of the first eukaryotic cells a series of defence mechanisms have evolved in order to secure cellular integrity, homeostasis and survival of the host. Invertebrates, ranging from protozoans to metazoans, possess cellular receptors which bind to foreign elements and differentiate self from non-self. This ability is in multicellular animals associated with presence of phagocytes, bearing different names (amoebocytes, haemocytes, coelomocytes) in various groups including animal sponges, worms, cnidarians, molluscs, crustaceans, chelicerates, insects and echinoderms (sea stars and urchins). Basically these cells have a macrophage like appearance and function and the repair and/or fight functions associated with these cells are prominent even at the earliest evolutionary stage. The cells possess Pathogen Recognition Receptors (PRRs) recognizing Pathogen Associated Molecular Patterns (PAMPS) which are well conserved molecular structures expressed by various pathogens (virus, bacteria, fungi, protozoans, helminths). Scavenger receptors, Toll-like receptors (TLRs) and Nod-like receptors (NLRs) are prominent representatives within this group of host receptors. Following receptor-ligand binding signal transduction initiates a complex cascade of cellular reactions which lead to production of one or more of a wide array of effector molecules. Cytokines take part in this orchestration of responses even in lower invertebrates which eventually may result in elimination or inactivation of the intruder. The evolutionary processes associated with these reactions are discussed." @default.
• W2146122014 created "2016-06-24" @default.
• W2146122014 creator A5019633791 @default.
• W2146122014 date "2014-09-23" @default.
• W2146122014 modified "2023-10-05" @default.
• W2146122014 title "Evolution of Innate Immunity: Clues from Invertebrates via Fish to Mammals" @default.
• W2146122014 cites W1530102179 @default.
• W2146122014 cites W1766025212 @default.
• W2146122014 cites W1766372943 @default.
• W2146122014 cites W1894895855 @default.
• W2146122014 cites W1963577601 @default.
• W2146122014 cites W1970945104 @default.
• W2146122014 cites W1971752655 @default.
• W2146122014 cites W1975456388 @default.
• W2146122014 cites W1975898784 @default.
• W2146122014 cites W1978361535 @default.
• W2146122014 cites W1987734377 @default.
• W2146122014 cites W1994503091 @default.
• W2146122014 cites W1996132657 @default.
• W2146122014 cites W1996540389 @default.
• W2146122014 cites W2002551740 @default.
• W2146122014 cites W2005634816 @default.
• W2146122014 cites W2009302452 @default.
• W2146122014 cites W2011926986 @default.
• W2146122014 cites W2012883564 @default.
• W2146122014 cites W2014308472 @default.
• W2146122014 cites W2017214965 @default.
• W2146122014 cites W2020726762 @default.
• W2146122014 cites W2023443921 @default.
• W2146122014 cites W2023889129 @default.
• W2146122014 cites W2025068684 @default.
• W2146122014 cites W2027065592 @default.
• W2146122014 cites W2030566090 @default.
• W2146122014 cites W2030972376 @default.
• W2146122014 cites W2034087823 @default.
• W2146122014 cites W2037358002 @default.
• W2146122014 cites W2040693501 @default.
• W2146122014 cites W2043225191 @default.
• W2146122014 cites W2044265338 @default.
• W2146122014 cites W2045596756 @default.
• W2146122014 cites W2045773810 @default.
• W2146122014 cites W2046293047 @default.
• W2146122014 cites W2048395086 @default.
• W2146122014 cites W2048859743 @default.
• W2146122014 cites W2053139786 @default.
• W2146122014 cites W2053845218 @default.
• W2146122014 cites W2061041720 @default.
• W2146122014 cites W2062984845 @default.
• W2146122014 cites W2065068661 @default.
• W2146122014 cites W2068151907 @default.
• W2146122014 cites W2069031048 @default.
• W2146122014 cites W2075909884 @default.
• W2146122014 cites W2080475151 @default.
• W2146122014 cites W2082606462 @default.
• W2146122014 cites W2095577918 @default.
• W2146122014 cites W2095622948 @default.
• W2146122014 cites W2102621913 @default.
• W2146122014 cites W2105359913 @default.
• W2146122014 cites W2106424856 @default.
• W2146122014 cites W2112841209 @default.
• W2146122014 cites W2112858189 @default.
• W2146122014 cites W2112888497 @default.
• W2146122014 cites W2115076706 @default.
• W2146122014 cites W2115572903 @default.
• W2146122014 cites W2122924489 @default.
• W2146122014 cites W2133393328 @default.
• W2146122014 cites W2134397885 @default.
• W2146122014 cites W2145399747 @default.
• W2146122014 cites W2164953421 @default.
• W2146122014 cites W2166110085 @default.
• W2146122014 cites W2166233585 @default.
• W2146122014 cites W2171760913 @default.
• W2146122014 cites W2180585235 @default.
• W2146122014 doi "https://doi.org/10.3389/fimmu.2014.00459" @default.
• W2146122014 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4172062" @default.
• W2146122014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25295041" @default.
• W2146122014 hasPublicationYear "2014" @default.
• W2146122014 type Work @default.
• W2146122014 sameAs 2146122014 @default.
• W2146122014 citedByCount "377" @default.
• W2146122014 countsByYear W21461220142015 @default.
• W2146122014 countsByYear W21461220142016 @default.
• W2146122014 countsByYear W21461220142017 @default.
• W2146122014 countsByYear W21461220142018 @default.
• W2146122014 countsByYear W21461220142019 @default.
• W2146122014 countsByYear W21461220142020 @default.
• W2146122014 countsByYear W21461220142021 @default.
• W2146122014 countsByYear W21461220142022 @default.
• W2146122014 countsByYear W21461220142023 @default.
• W2146122014 crossrefType "journal-article" @default.
• W2146122014 hasAuthorship W2146122014A5019633791 @default.
• W2146122014 hasBestOaLocation W21461220141 @default.
• W2146122014 hasConcept C104317684 @default.
• W2146122014 hasConcept C111289621 @default.
• W2146122014 hasConcept C136449434 @default.
• W2146122014 hasConcept C170493617 @default.
• W2146122014 hasConcept C188899842 @default.
• W2146122014 hasConcept C203014093 @default.
• W2146122014 hasConcept C51785407 @default.
• W2146122014 hasConcept C54355233 @default.

• next