Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146140960> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2146140960 endingPage "1725" @default.
- W2146140960 startingPage "1723" @default.
- W2146140960 abstract "<b>Background:</b> Baló’s concentric sclerosis (BCS) is a demyelinating disorder believed to be a rare variant of multiple sclerosis (MS). Human herpesvirus 6 (HHV-6) is a highly neurotropic virus causing severe central nervous system (CNS) infections predominantly following reactivation of latent HHV-6 in immunocompromised individuals. Primary infection with HHV-6 usually occurs in early childhood manifesting as exanthema subitum. The clinical spectrum of primary infection in adolescents or adults has not yet been evaluated. <b>Case report:</b> A previously healthy 13 year old girl developed acute hemianopsia and anomia 5 days after an episode of fever and malaise of unknown origin. Cerebral MRI revealed three white matter lesions, one with ring-like contrast enhancement. Lumbar puncture showed mononuclear pleocytosis of 30 cells/µl, oligoclonal IgG, and a normal protein level. Follow up cerebral MRI scans revealed lamellar concentric hemispheric lesions characteristic of BCS. The first neurological symptoms of the patient coincided with primary HHV-6 CNS infection, diagnosed by a positive PCR test of the CSF together with seroconversion. Response to antiviral and corticosteroid treatment was only temporary, but immunoglobulin treatment has so far been followed by clinical stability for 30 months. <b>Conclusions:</b> To our knowledge, this is the first report both of an association between HHV-6 and BCS and of immunoglobulin treatment of BCS. A late primary infection with HHV-6 might be associated with BCS. Further studies in patients with this rare disease are needed to confirm this association and to evaluate the efficacy of antiviral and immunoglobulin treatment." @default.
- W2146140960 created "2016-06-24" @default.
- W2146140960 creator A5048266882 @default.
- W2146140960 date "2005-12-01" @default.
- W2146140960 modified "2023-10-15" @default.
- W2146140960 title "Balo's concentric sclerosis associated with primary human herpesvirus 6 infection" @default.
- W2146140960 cites W1876300997 @default.
- W2146140960 cites W190496852 @default.
- W2146140960 cites W1969929508 @default.
- W2146140960 cites W1982872317 @default.
- W2146140960 cites W1993403217 @default.
- W2146140960 cites W2003793374 @default.
- W2146140960 cites W2008999973 @default.
- W2146140960 cites W2010054542 @default.
- W2146140960 cites W2013194125 @default.
- W2146140960 cites W2024228465 @default.
- W2146140960 cites W2032583606 @default.
- W2146140960 cites W2055390213 @default.
- W2146140960 cites W2059265106 @default.
- W2146140960 cites W2076781069 @default.
- W2146140960 cites W2080270161 @default.
- W2146140960 cites W2080547419 @default.
- W2146140960 cites W2096555252 @default.
- W2146140960 cites W2107551422 @default.
- W2146140960 cites W2108658900 @default.
- W2146140960 cites W2147062889 @default.
- W2146140960 cites W2158476830 @default.
- W2146140960 cites W2345547772 @default.
- W2146140960 cites W2471103592 @default.
- W2146140960 doi "https://doi.org/10.1136/jnnp.2004.062331" @default.
- W2146140960 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1739441" @default.
- W2146140960 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16291903" @default.
- W2146140960 hasPublicationYear "2005" @default.
- W2146140960 type Work @default.
- W2146140960 sameAs 2146140960 @default.
- W2146140960 citedByCount "31" @default.
- W2146140960 countsByYear W21461409602012 @default.
- W2146140960 countsByYear W21461409602013 @default.
- W2146140960 countsByYear W21461409602014 @default.
- W2146140960 countsByYear W21461409602015 @default.
- W2146140960 countsByYear W21461409602016 @default.
- W2146140960 countsByYear W21461409602017 @default.
- W2146140960 countsByYear W21461409602018 @default.
- W2146140960 countsByYear W21461409602019 @default.
- W2146140960 countsByYear W21461409602020 @default.
- W2146140960 countsByYear W21461409602021 @default.
- W2146140960 countsByYear W21461409602023 @default.
- W2146140960 crossrefType "journal-article" @default.
- W2146140960 hasAuthorship W2146140960A5048266882 @default.
- W2146140960 hasBestOaLocation W21461409601 @default.
- W2146140960 hasConcept C142724271 @default.
- W2146140960 hasConcept C159654299 @default.
- W2146140960 hasConcept C203014093 @default.
- W2146140960 hasConcept C2522874641 @default.
- W2146140960 hasConcept C2777451964 @default.
- W2146140960 hasConcept C2777483564 @default.
- W2146140960 hasConcept C2779651940 @default.
- W2146140960 hasConcept C2780640218 @default.
- W2146140960 hasConcept C71924100 @default.
- W2146140960 hasConcept C83455156 @default.
- W2146140960 hasConceptScore W2146140960C142724271 @default.
- W2146140960 hasConceptScore W2146140960C159654299 @default.
- W2146140960 hasConceptScore W2146140960C203014093 @default.
- W2146140960 hasConceptScore W2146140960C2522874641 @default.
- W2146140960 hasConceptScore W2146140960C2777451964 @default.
- W2146140960 hasConceptScore W2146140960C2777483564 @default.
- W2146140960 hasConceptScore W2146140960C2779651940 @default.
- W2146140960 hasConceptScore W2146140960C2780640218 @default.
- W2146140960 hasConceptScore W2146140960C71924100 @default.
- W2146140960 hasConceptScore W2146140960C83455156 @default.
- W2146140960 hasIssue "12" @default.
- W2146140960 hasLocation W21461409601 @default.
- W2146140960 hasLocation W21461409602 @default.
- W2146140960 hasLocation W21461409603 @default.
- W2146140960 hasLocation W21461409604 @default.
- W2146140960 hasOpenAccess W2146140960 @default.
- W2146140960 hasPrimaryLocation W21461409601 @default.
- W2146140960 hasRelatedWork W1699798236 @default.
- W2146140960 hasRelatedWork W1795998351 @default.
- W2146140960 hasRelatedWork W1996892527 @default.
- W2146140960 hasRelatedWork W2021221603 @default.
- W2146140960 hasRelatedWork W2060573533 @default.
- W2146140960 hasRelatedWork W2791140317 @default.
- W2146140960 hasRelatedWork W3128118216 @default.
- W2146140960 hasRelatedWork W4206105795 @default.
- W2146140960 hasRelatedWork W4206253394 @default.
- W2146140960 hasRelatedWork W4290974566 @default.
- W2146140960 hasVolume "76" @default.
- W2146140960 isParatext "false" @default.
- W2146140960 isRetracted "false" @default.
- W2146140960 magId "2146140960" @default.
- W2146140960 workType "article" @default.