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- W2146154060 abstract "<h3>To the Editor.—</h3> In the January 1985Archives, Levine et al<sup>1</sup>reported the occurrence of acral erythema during therapy for severe myelogenous leukemia. We have made similar observations and would like to contribute additional information. The patients described by Levine et al were all receiving combination chemotherapy, and the authors did not ascribe the reaction to any single agent. Acral erythema is not a specific reaction to one agent and has been reported in patients given cytarabine,<sup>2</sup>doxorubicin,<sup>3</sup>fluorouracil,<sup>3</sup>and methotrexate<sup>4</sup>alone. However, in the cases reported by Levine et al, the reaction was almost certainly to cytarabine, because acral erythema secondary to doxorubicin has been described only in association with constant infusions, which were not used in these cases. Furthermore, acral erythema is being noted with increasing frequency now that cytarabine is being given in higher dosages than those used in the past; we agree that the reaction is toxic and we suggest, with respect to cytarabine" @default.
- W2146154060 created "2016-06-24" @default.
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- W2146154060 date "1985-10-01" @default.
- W2146154060 modified "2023-09-24" @default.
- W2146154060 title "Cytarabine-Induced Palmar-Plantar Erythema" @default.
- W2146154060 cites W1964304871 @default.
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- W2146154060 doi "https://doi.org/10.1001/archderm.1985.01660100020006" @default.
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