FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146221750> ?p ?o ?g. }

• W2146221750 endingPage "3579" @default.
• W2146221750 startingPage "3572" @default.
• W2146221750 abstract "Abstract The study aimed to determine the effects of parthenolide (PAR) on bone volume (BV) and bone surface resorption as assessed by live‐animal microcomputed tomography (μCT) and possible osteocyte death as indicated by empty lacunae histologically in polyethylene (PE) particle‐induced calvarial osteolysis in mice. Baseline μCT scans were conducted 7 days preimplantation of 2 × 10 8 PE particles/mL over the calvariae (day 0). PAR at 1 mg/kg/day was subcutaneously injected on days 0, 4, 7, and 10. At day 14, BV and surface resorption was analyzed with μCT. Calvarial tissue was processed for histomorphometric osteocyte evaluation. Serum was analyzed for type‐1 carboxy‐terminal collagen crosslinks (CTX‐1) and osteoclast associated receptor (OSCAR) levels by ELISA. PE significantly decreased BV ( p = 0.0368), increased surface bone resorption area ( p = 0.0022), and increased the percentage of empty lacunae ( p = 0.0043). Interestingly, PAR significantly reduced the resorption surface area ( p = 0.0022) and the percentage of empty osteocyte lacunae ( p = 0.0087) in the PE‐calvariae, but it did not affect BV, serum CTX‐1 or OSCAR levels. The ability of PAR to inhibit PE‐induced surface bone erosion may better reflect the in vivo situation, where bone resorption occurs on the surface at the bone‐implant interface and may also be related to the role of osteocytes in this pathology. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 103A: 3572–3579, 2015." @default.
• W2146221750 created "2016-06-24" @default.
• W2146221750 creator A5011056560 @default.
• W2146221750 creator A5017365255 @default.
• W2146221750 creator A5021592147 @default.
• W2146221750 creator A5026855073 @default.
• W2146221750 creator A5047426616 @default.
• W2146221750 creator A5052387305 @default.
• W2146221750 creator A5070137364 @default.
• W2146221750 creator A5070570063 @default.
• W2146221750 creator A5084262507 @default.
• W2146221750 date "2015-05-29" @default.
• W2146221750 modified "2023-10-06" @default.
• W2146221750 title "Parthenolide reduces empty lacunae and osteoclastic bone surface resorption induced by polyethylene particles in a murine calvarial model of peri-implant osteolysis" @default.
• W2146221750 cites W1599887895 @default.
• W2146221750 cites W180986551 @default.
• W2146221750 cites W1849994368 @default.
• W2146221750 cites W1926885326 @default.
• W2146221750 cites W1931335837 @default.
• W2146221750 cites W1934874004 @default.
• W2146221750 cites W1982151917 @default.
• W2146221750 cites W1986781047 @default.
• W2146221750 cites W1990481372 @default.
• W2146221750 cites W1991012844 @default.
• W2146221750 cites W1991552535 @default.
• W2146221750 cites W1995269092 @default.
• W2146221750 cites W1999811942 @default.
• W2146221750 cites W2003581234 @default.
• W2146221750 cites W2020238012 @default.
• W2146221750 cites W2030603916 @default.
• W2146221750 cites W2031057814 @default.
• W2146221750 cites W2032296791 @default.
• W2146221750 cites W2038306197 @default.
• W2146221750 cites W2055372799 @default.
• W2146221750 cites W2057240308 @default.
• W2146221750 cites W2064346787 @default.
• W2146221750 cites W2081748489 @default.
• W2146221750 cites W2082976429 @default.
• W2146221750 cites W2083185600 @default.
• W2146221750 cites W2086894618 @default.
• W2146221750 cites W2087974513 @default.
• W2146221750 cites W2101886066 @default.
• W2146221750 cites W2114552825 @default.
• W2146221750 cites W2117725515 @default.
• W2146221750 cites W2136254777 @default.
• W2146221750 cites W2144106301 @default.
• W2146221750 cites W2152886100 @default.
• W2146221750 cites W2155407923 @default.
• W2146221750 cites W2157447805 @default.
• W2146221750 cites W2179560225 @default.
• W2146221750 doi "https://doi.org/10.1002/jbm.a.35484" @default.
• W2146221750 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25903444" @default.
• W2146221750 hasPublicationYear "2015" @default.
• W2146221750 type Work @default.
• W2146221750 sameAs 2146221750 @default.
• W2146221750 citedByCount "15" @default.
• W2146221750 countsByYear W21462217502015 @default.
• W2146221750 countsByYear W21462217502017 @default.
• W2146221750 countsByYear W21462217502018 @default.
• W2146221750 countsByYear W21462217502020 @default.
• W2146221750 countsByYear W21462217502021 @default.
• W2146221750 countsByYear W21462217502022 @default.
• W2146221750 countsByYear W21462217502023 @default.
• W2146221750 crossrefType "journal-article" @default.
• W2146221750 hasAuthorship W2146221750A5011056560 @default.
• W2146221750 hasAuthorship W2146221750A5017365255 @default.
• W2146221750 hasAuthorship W2146221750A5021592147 @default.
• W2146221750 hasAuthorship W2146221750A5026855073 @default.
• W2146221750 hasAuthorship W2146221750A5047426616 @default.
• W2146221750 hasAuthorship W2146221750A5052387305 @default.
• W2146221750 hasAuthorship W2146221750A5070137364 @default.
• W2146221750 hasAuthorship W2146221750A5070570063 @default.
• W2146221750 hasAuthorship W2146221750A5084262507 @default.
• W2146221750 hasConcept C126322002 @default.
• W2146221750 hasConcept C134018914 @default.
• W2146221750 hasConcept C141071460 @default.
• W2146221750 hasConcept C146562846 @default.
• W2146221750 hasConcept C150903083 @default.
• W2146221750 hasConcept C170493617 @default.
• W2146221750 hasConcept C185592680 @default.
• W2146221750 hasConcept C192562407 @default.
• W2146221750 hasConcept C199343813 @default.
• W2146221750 hasConcept C202751555 @default.
• W2146221750 hasConcept C207001950 @default.
• W2146221750 hasConcept C2776033226 @default.
• W2146221750 hasConcept C2778260815 @default.
• W2146221750 hasConcept C2780973866 @default.
• W2146221750 hasConcept C2781282405 @default.
• W2146221750 hasConcept C2781411149 @default.
• W2146221750 hasConcept C55493867 @default.
• W2146221750 hasConcept C673006 @default.
• W2146221750 hasConcept C71924100 @default.
• W2146221750 hasConcept C86803240 @default.
• W2146221750 hasConceptScore W2146221750C126322002 @default.
• W2146221750 hasConceptScore W2146221750C134018914 @default.
• W2146221750 hasConceptScore W2146221750C141071460 @default.
• W2146221750 hasConceptScore W2146221750C146562846 @default.
• W2146221750 hasConceptScore W2146221750C150903083 @default.

• next