Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146228110> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2146228110 endingPage "465" @default.
- W2146228110 startingPage "459" @default.
- W2146228110 abstract "When nuclei were isolated from exponentially growing HeLa S3 cells immediately after a treatment with hyperthermia and/or procaine-HCl, an increase in nuclear protein binding was observed. The extent of this increase, however, did not correlate with cell survival under all conditions of the various treatments. For example, an increase up to 40 per cent in nuclear protein binding as a result of procaine treatment did not lead to a decrease of survival, while a 40 per cent increase of nuclear protein binding as a result of hyperthermia corresponded with over 90 per cent cell killing. In addition the extent of heat-induced enhancement of nuclear protein content was approximately equal for thermotolerant and heated control cells, or for cells heated in the presence of procaine.The rate of decay in nuclear protein binding upon post-heat incubations at 37°C of the cells, however, was enhanced in tolerant cells and retarded in cells heated in the presence of procaine as compared to heated control cells.These results show that, in spite of suggestions in other reports, neither the initial rate of enhanced protein binding nor the extent of the protein bound to the nucleus seems a reliable measure for heat toxicity. The capacity of the cell to reverse this heat-induced protein binding must be considered." @default.
- W2146228110 created "2016-06-24" @default.
- W2146228110 creator A5042480102 @default.
- W2146228110 creator A5058204719 @default.
- W2146228110 creator A5075686085 @default.
- W2146228110 date "1987-01-01" @default.
- W2146228110 modified "2023-09-25" @default.
- W2146228110 title "Heat-induced nuclear protein binding and its relation to thermal cytotoxicity" @default.
- W2146228110 cites W1775749144 @default.
- W2146228110 cites W1966048184 @default.
- W2146228110 cites W1978484455 @default.
- W2146228110 cites W2064821945 @default.
- W2146228110 cites W2086483638 @default.
- W2146228110 cites W2087675686 @default.
- W2146228110 cites W2094742295 @default.
- W2146228110 cites W2120327661 @default.
- W2146228110 cites W2140964400 @default.
- W2146228110 cites W2318882977 @default.
- W2146228110 cites W2321819873 @default.
- W2146228110 cites W2332910302 @default.
- W2146228110 cites W4298355886 @default.
- W2146228110 doi "https://doi.org/10.3109/02656738709140416" @default.
- W2146228110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3681046" @default.
- W2146228110 hasPublicationYear "1987" @default.
- W2146228110 type Work @default.
- W2146228110 sameAs 2146228110 @default.
- W2146228110 citedByCount "42" @default.
- W2146228110 countsByYear W21462281102018 @default.
- W2146228110 countsByYear W21462281102020 @default.
- W2146228110 crossrefType "journal-article" @default.
- W2146228110 hasAuthorship W2146228110A5042480102 @default.
- W2146228110 hasAuthorship W2146228110A5058204719 @default.
- W2146228110 hasAuthorship W2146228110A5075686085 @default.
- W2146228110 hasConcept C104317684 @default.
- W2146228110 hasConcept C12554922 @default.
- W2146228110 hasConcept C1491633281 @default.
- W2146228110 hasConcept C151730666 @default.
- W2146228110 hasConcept C185592680 @default.
- W2146228110 hasConcept C2777366897 @default.
- W2146228110 hasConcept C2779828710 @default.
- W2146228110 hasConcept C2779949491 @default.
- W2146228110 hasConcept C2780723820 @default.
- W2146228110 hasConcept C29512474 @default.
- W2146228110 hasConcept C3675279 @default.
- W2146228110 hasConcept C553089730 @default.
- W2146228110 hasConcept C55493867 @default.
- W2146228110 hasConcept C86339819 @default.
- W2146228110 hasConcept C86803240 @default.
- W2146228110 hasConcept C95444343 @default.
- W2146228110 hasConcept C98274493 @default.
- W2146228110 hasConceptScore W2146228110C104317684 @default.
- W2146228110 hasConceptScore W2146228110C12554922 @default.
- W2146228110 hasConceptScore W2146228110C1491633281 @default.
- W2146228110 hasConceptScore W2146228110C151730666 @default.
- W2146228110 hasConceptScore W2146228110C185592680 @default.
- W2146228110 hasConceptScore W2146228110C2777366897 @default.
- W2146228110 hasConceptScore W2146228110C2779828710 @default.
- W2146228110 hasConceptScore W2146228110C2779949491 @default.
- W2146228110 hasConceptScore W2146228110C2780723820 @default.
- W2146228110 hasConceptScore W2146228110C29512474 @default.
- W2146228110 hasConceptScore W2146228110C3675279 @default.
- W2146228110 hasConceptScore W2146228110C553089730 @default.
- W2146228110 hasConceptScore W2146228110C55493867 @default.
- W2146228110 hasConceptScore W2146228110C86339819 @default.
- W2146228110 hasConceptScore W2146228110C86803240 @default.
- W2146228110 hasConceptScore W2146228110C95444343 @default.
- W2146228110 hasConceptScore W2146228110C98274493 @default.
- W2146228110 hasIssue "5" @default.
- W2146228110 hasLocation W21462281101 @default.
- W2146228110 hasLocation W21462281102 @default.
- W2146228110 hasOpenAccess W2146228110 @default.
- W2146228110 hasPrimaryLocation W21462281101 @default.
- W2146228110 hasRelatedWork W2010045738 @default.
- W2146228110 hasRelatedWork W2055864760 @default.
- W2146228110 hasRelatedWork W2062729894 @default.
- W2146228110 hasRelatedWork W2063569384 @default.
- W2146228110 hasRelatedWork W2065572766 @default.
- W2146228110 hasRelatedWork W2094295286 @default.
- W2146228110 hasRelatedWork W2146228110 @default.
- W2146228110 hasRelatedWork W2333343744 @default.
- W2146228110 hasRelatedWork W3030376755 @default.
- W2146228110 hasRelatedWork W4253445568 @default.
- W2146228110 hasVolume "3" @default.
- W2146228110 isParatext "false" @default.
- W2146228110 isRetracted "false" @default.
- W2146228110 magId "2146228110" @default.
- W2146228110 workType "article" @default.