FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146240170> ?p ?o ?g. }

• W2146240170 endingPage "176" @default.
• W2146240170 startingPage "163" @default.
• W2146240170 abstract "Although relatively effective diagnostic tests for brucellosis have been in existence for more than 100 years, it remains a serious, embedded and also a re-emerging disease in many parts of the globe. There are many factors besides suboptimal diagnosis that impede the complete and sustained eradication of animal brucellosis. In this review a case for the continued improvement of diagnostic methods is made through identifying existing shortcomings and considering what impact these have upon control and eradication. The focus is on developments in immunodiagnostics as these seem more likely to yield the pragmatic solutions needed. Moreover, developments in DNA detection methods have been neatly and recently reviewed elsewhere. This article reviews issues such as test cost, mobility, sensitivity and specificity. Advances in low-cost materials, high-throughput testing, assay multiplexing and the quantification of pen-side tests are described and their relevance to disease control considered. Poor test specificity when resolving positive serology, due to infection with cross-reactive bacteria and vaccination with smooth Brucella strains, is also an impediment to efficient disease eradication. A case for the development of novel discrete epitope antigens to address this is presented alongside in silico methods of selection and tools that enable increased analytical sensitivity that may be required to detect relatively low, but potentially significant, analytes. References have been drawn from the study of brucellosis wherever possible. However, in some cases new technological developments worthy of discussion have been included via the use of pertinent alternative examples. In conclusion, despite developments and innovations the classical serological tests seem under no imminent danger of mass extinction but there is potential for significant improvement and supplementation." @default.
• W2146240170 created "2016-06-24" @default.
• W2146240170 creator A5080588851 @default.
• W2146240170 date "2013-04-01" @default.
• W2146240170 modified "2023-09-25" @default.
• W2146240170 title "New developments in the immunodiagnosis of brucellosis in livestock and wildlife" @default.
• W2146240170 cites W132200495 @default.
• W2146240170 cites W1487178589 @default.
• W2146240170 cites W179599380 @default.
• W2146240170 cites W1851157453 @default.
• W2146240170 cites W1913092736 @default.
• W2146240170 cites W1970823195 @default.
• W2146240170 cites W1975230963 @default.
• W2146240170 cites W1977093496 @default.
• W2146240170 cites W1982439159 @default.
• W2146240170 cites W1987737132 @default.
• W2146240170 cites W1989294263 @default.
• W2146240170 cites W1990734263 @default.
• W2146240170 cites W1992447641 @default.
• W2146240170 cites W1993887481 @default.
• W2146240170 cites W1994551371 @default.
• W2146240170 cites W2000967739 @default.
• W2146240170 cites W2002863550 @default.
• W2146240170 cites W2002993469 @default.
• W2146240170 cites W2004842601 @default.
• W2146240170 cites W2005632962 @default.
• W2146240170 cites W2005690092 @default.
• W2146240170 cites W2010982616 @default.
• W2146240170 cites W2015681141 @default.
• W2146240170 cites W2019512512 @default.
• W2146240170 cites W2020849869 @default.
• W2146240170 cites W2023850468 @default.
• W2146240170 cites W2024765222 @default.
• W2146240170 cites W2027456107 @default.
• W2146240170 cites W2031929435 @default.
• W2146240170 cites W2031935674 @default.
• W2146240170 cites W2034443218 @default.
• W2146240170 cites W2034765632 @default.
• W2146240170 cites W2034781603 @default.
• W2146240170 cites W2037550429 @default.
• W2146240170 cites W2042683431 @default.
• W2146240170 cites W2045030846 @default.
• W2146240170 cites W2051265367 @default.
• W2146240170 cites W2053011057 @default.
• W2146240170 cites W2054160273 @default.
• W2146240170 cites W2057725451 @default.
• W2146240170 cites W2060907336 @default.
• W2146240170 cites W2064561451 @default.
• W2146240170 cites W2070266800 @default.
• W2146240170 cites W2071509039 @default.
• W2146240170 cites W2072363775 @default.
• W2146240170 cites W2077788834 @default.
• W2146240170 cites W2078266360 @default.
• W2146240170 cites W2079501066 @default.
• W2146240170 cites W2082402668 @default.
• W2146240170 cites W2082995341 @default.
• W2146240170 cites W2083580953 @default.
• W2146240170 cites W2099376142 @default.
• W2146240170 cites W2102283548 @default.
• W2146240170 cites W2107727389 @default.
• W2146240170 cites W2109643853 @default.
• W2146240170 cites W2112649975 @default.
• W2146240170 cites W2114676409 @default.
• W2146240170 cites W2117181068 @default.
• W2146240170 cites W2120919992 @default.
• W2146240170 cites W2121906176 @default.
• W2146240170 cites W2123061071 @default.
• W2146240170 cites W2123264732 @default.
• W2146240170 cites W2130723974 @default.
• W2146240170 cites W2134361954 @default.
• W2146240170 cites W2134520443 @default.
• W2146240170 cites W2135058277 @default.
• W2146240170 cites W2136658736 @default.
• W2146240170 cites W2152101461 @default.
• W2146240170 cites W2155107980 @default.
• W2146240170 cites W2158711371 @default.
• W2146240170 cites W2167220211 @default.
• W2146240170 cites W2326135545 @default.
• W2146240170 doi "https://doi.org/10.20506/rst.32.1.2205" @default.
• W2146240170 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23837374" @default.
• W2146240170 hasPublicationYear "2013" @default.
• W2146240170 type Work @default.
• W2146240170 sameAs 2146240170 @default.
• W2146240170 citedByCount "32" @default.
• W2146240170 countsByYear W21462401702013 @default.
• W2146240170 countsByYear W21462401702014 @default.
• W2146240170 countsByYear W21462401702015 @default.
• W2146240170 countsByYear W21462401702016 @default.
• W2146240170 countsByYear W21462401702017 @default.
• W2146240170 countsByYear W21462401702018 @default.
• W2146240170 countsByYear W21462401702019 @default.
• W2146240170 countsByYear W21462401702020 @default.
• W2146240170 countsByYear W21462401702021 @default.
• W2146240170 countsByYear W21462401702022 @default.
• W2146240170 countsByYear W21462401702023 @default.
• W2146240170 crossrefType "journal-article" @default.
• W2146240170 hasAuthorship W2146240170A5080588851 @default.
• W2146240170 hasConcept C112930515 @default.

• next