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• W2146293602 abstract "A high incidence of albuminuria, varying by ethnicity, has been found in a number of populations worldwide. There have been few opportunities to explore the prevalence of albuminuria as a marker of chronic kidney disease while adjusting for other risk factors in the different ethnic groups in New Zealand. We examined the association between albuminuria and ethnicity using cross-sectional data from a large cohort study of type 2 diabetes conducted in New Zealand. The study population was 65 171 adults in primary care with type 2 diabetes, not on renal replacement therapy; median age was 64.7 years, median diabetes duration 5.1 years and 48.5% were non-European. Microalbuminuria or greater was present in 50% of Maori, 49% of Pacific people, 31% of Indo- and East-Asians and 28% of Europeans. Regression analyses were used to examine the association between ethnicity and albuminuria—measured as albumin:creatinine ratio—after controlling for study site and other known risk variables: age, sex, duration of diabetes, smoking status, socioeconomic status, body mass index, systolic and diastolic blood pressure, triglyceride levels, HbA 1C and being on an angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker. After controlling for these risk factors and compared with Europeans, odds ratios for ‘advanced’ albuminuria (≥100 mg/mmol) were 3.9 (95% confidence interval: 3.2–4.6) in Maori, 4.7 (3.6–6.3) in Pacific people, 2.0 (1.5–2.7) in Indo-Asians and 4.1 (3.2–5.1) in East-Asians. Non-European ethnicities appear to carry significantly higher risks of albuminuria in type 2 diabetes." @default.
• W2146293602 created "2016-06-24" @default.
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• W2146293602 date "2011-09-13" @default.
• W2146293602 modified "2023-09-27" @default.
• W2146293602 title "Increased prevalence of albuminuria among non-European peoples with type 2 diabetes" @default.
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• W2146293602 doi "https://doi.org/10.1093/ndt/gfr540" @default.
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