Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146333225> ?p ?o ?g. }
- W2146333225 endingPage "28" @default.
- W2146333225 startingPage "28" @default.
- W2146333225 abstract "Existing quantitative models of mouse cerebral cortical development are not fully constrained by experimental data.Here, we use simple difference equations to model neural progenitor cell fate decisions, incorporating intermediate progenitor cells and initially low rates of neural progenitor cell death. Also, we conduct a sensitivity analysis to investigate possible uncertainty in the fraction of cells that divide, differentiate, and die at each cell cycle.We demonstrate that uniformly low-level neural progenitor cell death, as concluded in previous models, is incompatible with normal mouse cortical development. Levels of neural progenitor cell death up to and exceeding 50% are compatible with normal cortical development and may operate to prevent forebrain overgrowth as observed following cell death attenuation, as occurs in caspase 3-null mutant mice." @default.
- W2146333225 created "2016-06-24" @default.
- W2146333225 creator A5014799222 @default.
- W2146333225 creator A5029782896 @default.
- W2146333225 creator A5037802665 @default.
- W2146333225 date "2009-01-01" @default.
- W2146333225 modified "2023-09-27" @default.
- W2146333225 title "Mathematical modeling supports substantial mouse neural progenitor cell death" @default.
- W2146333225 cites W109647353 @default.
- W2146333225 cites W1500073381 @default.
- W2146333225 cites W1516412274 @default.
- W2146333225 cites W1559406855 @default.
- W2146333225 cites W1582081614 @default.
- W2146333225 cites W1671067214 @default.
- W2146333225 cites W1884108341 @default.
- W2146333225 cites W1953301620 @default.
- W2146333225 cites W1965681567 @default.
- W2146333225 cites W1970756199 @default.
- W2146333225 cites W1975003415 @default.
- W2146333225 cites W1975466959 @default.
- W2146333225 cites W1981164058 @default.
- W2146333225 cites W1987785848 @default.
- W2146333225 cites W1988976106 @default.
- W2146333225 cites W1990935914 @default.
- W2146333225 cites W1992089991 @default.
- W2146333225 cites W1998454877 @default.
- W2146333225 cites W1999334134 @default.
- W2146333225 cites W2000352412 @default.
- W2146333225 cites W2000894919 @default.
- W2146333225 cites W2005402594 @default.
- W2146333225 cites W2016851798 @default.
- W2146333225 cites W2019260069 @default.
- W2146333225 cites W2019276937 @default.
- W2146333225 cites W2024086907 @default.
- W2146333225 cites W2025968815 @default.
- W2146333225 cites W2039600900 @default.
- W2146333225 cites W2042279121 @default.
- W2146333225 cites W2049873418 @default.
- W2146333225 cites W2054316139 @default.
- W2146333225 cites W2056164750 @default.
- W2146333225 cites W2057722433 @default.
- W2146333225 cites W2061491996 @default.
- W2146333225 cites W2089124709 @default.
- W2146333225 cites W2089403382 @default.
- W2146333225 cites W2104876599 @default.
- W2146333225 cites W2110300663 @default.
- W2146333225 cites W2119742125 @default.
- W2146333225 cites W2127220436 @default.
- W2146333225 cites W2127714237 @default.
- W2146333225 cites W2130446433 @default.
- W2146333225 cites W2142458121 @default.
- W2146333225 cites W2145186752 @default.
- W2146333225 cites W2147471332 @default.
- W2146333225 cites W2152084055 @default.
- W2146333225 cites W2158255377 @default.
- W2146333225 cites W2167700185 @default.
- W2146333225 cites W2171499108 @default.
- W2146333225 cites W2172176015 @default.
- W2146333225 cites W2172202356 @default.
- W2146333225 cites W2335622476 @default.
- W2146333225 cites W3011730451 @default.
- W2146333225 doi "https://doi.org/10.1186/1749-8104-4-28" @default.
- W2146333225 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2729736" @default.
- W2146333225 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19602274" @default.
- W2146333225 hasPublicationYear "2009" @default.
- W2146333225 type Work @default.
- W2146333225 sameAs 2146333225 @default.
- W2146333225 citedByCount "16" @default.
- W2146333225 countsByYear W21463332252012 @default.
- W2146333225 countsByYear W21463332252013 @default.
- W2146333225 countsByYear W21463332252014 @default.
- W2146333225 countsByYear W21463332252015 @default.
- W2146333225 countsByYear W21463332252016 @default.
- W2146333225 countsByYear W21463332252017 @default.
- W2146333225 countsByYear W21463332252018 @default.
- W2146333225 countsByYear W21463332252019 @default.
- W2146333225 countsByYear W21463332252021 @default.
- W2146333225 countsByYear W21463332252023 @default.
- W2146333225 crossrefType "journal-article" @default.
- W2146333225 hasAuthorship W2146333225A5014799222 @default.
- W2146333225 hasAuthorship W2146333225A5029782896 @default.
- W2146333225 hasAuthorship W2146333225A5037802665 @default.
- W2146333225 hasBestOaLocation W21463332251 @default.
- W2146333225 hasConcept C104317684 @default.
- W2146333225 hasConcept C136834591 @default.
- W2146333225 hasConcept C15729860 @default.
- W2146333225 hasConcept C163952510 @default.
- W2146333225 hasConcept C169760540 @default.
- W2146333225 hasConcept C190283241 @default.
- W2146333225 hasConcept C201750760 @default.
- W2146333225 hasConcept C2779715522 @default.
- W2146333225 hasConcept C28328180 @default.
- W2146333225 hasConcept C31573885 @default.
- W2146333225 hasConcept C529278444 @default.
- W2146333225 hasConcept C54355233 @default.
- W2146333225 hasConcept C86339819 @default.
- W2146333225 hasConcept C86803240 @default.
- W2146333225 hasConcept C95444343 @default.