FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146335280> ?p ?o ?g. }

• W2146335280 endingPage "462" @default.
• W2146335280 startingPage "451" @default.
• W2146335280 abstract "BACKGROUND: The release of vesicles by red blood cells (RBCs) occurs in vivo and in vitro under various conditions. Vesiculation also takes place during RBC storage and results in the accumulation of vesicles in RBC units. The membrane protein composition of the storage-associated vesicles has not been studied in detail. The characterization of the vesicular membrane might hint at the underlying mechanism of the storage-associated changes in general and the vesiculation process in particular. STUDY DESIGN AND METHODS: Vesicles from RBCs that had been stored for various periods were isolated and RBCs of the same RBC units were used to generate calcium-induced microvesicles. These two vesicle types were compared with respect to their size with atomic force microscopy, their raft protein content with detergent-resistant membrane (DRM) analysis, and their thrombogenic potential and activity with annexin V binding and thrombin generation, respectively. RESULTS: The storage-associated vesicles and the calcium-induced microvesicles are similar in size, in thrombogenic activity, and in membrane protein composition. The major differences were the relative concentrations of the major integral DRM proteins. In storage-associated vesicles, stomatin is twofold enriched and flotillin-2 is threefold depleted. CONCLUSION: These data indicate that a stomatin-specific, raft-based process is involved in storage-associated vesiculation. A model of the vesiculation process in RBCs is proposed considering the raft-stabilizing properties of stomatin, the low storage temperature favoring raft aggregation, and the previously reported storage-associated changes in the cytoskeletal organization." @default.
• W2146335280 created "2016-06-24" @default.
• W2146335280 creator A5002494487 @default.
• W2146335280 creator A5007608468 @default.
• W2146335280 creator A5011017158 @default.
• W2146335280 creator A5017035150 @default.
• W2146335280 creator A5037494404 @default.
• W2146335280 creator A5042727914 @default.
• W2146335280 creator A5054678441 @default.
• W2146335280 creator A5068436495 @default.
• W2146335280 date "2008-03-01" @default.
• W2146335280 modified "2023-09-24" @default.
• W2146335280 title "Vesicles generated during storage of red cells are rich in the lipid raft marker stomatin" @default.
• W2146335280 cites W118860408 @default.
• W2146335280 cites W1521830831 @default.
• W2146335280 cites W180072956 @default.
• W2146335280 cites W1922086062 @default.
• W2146335280 cites W1972261887 @default.
• W2146335280 cites W1973791258 @default.
• W2146335280 cites W1973933701 @default.
• W2146335280 cites W1974041214 @default.
• W2146335280 cites W1974926560 @default.
• W2146335280 cites W1975473392 @default.
• W2146335280 cites W1977004640 @default.
• W2146335280 cites W1977689290 @default.
• W2146335280 cites W1978318476 @default.
• W2146335280 cites W1985365711 @default.
• W2146335280 cites W1989176457 @default.
• W2146335280 cites W1993745463 @default.
• W2146335280 cites W2010721093 @default.
• W2146335280 cites W2011852955 @default.
• W2146335280 cites W2014903703 @default.
• W2146335280 cites W2015716416 @default.
• W2146335280 cites W2017905022 @default.
• W2146335280 cites W2018575885 @default.
• W2146335280 cites W2019211895 @default.
• W2146335280 cites W2026856965 @default.
• W2146335280 cites W2028235792 @default.
• W2146335280 cites W2032145912 @default.
• W2146335280 cites W2037141054 @default.
• W2146335280 cites W2045735176 @default.
• W2146335280 cites W2046151550 @default.
• W2146335280 cites W2050531468 @default.
• W2146335280 cites W2051331576 @default.
• W2146335280 cites W2051545925 @default.
• W2146335280 cites W2051763915 @default.
• W2146335280 cites W2058637122 @default.
• W2146335280 cites W2064499756 @default.
• W2146335280 cites W2065196084 @default.
• W2146335280 cites W2069232833 @default.
• W2146335280 cites W2071456460 @default.
• W2146335280 cites W2074414510 @default.
• W2146335280 cites W2076381473 @default.
• W2146335280 cites W2080372153 @default.
• W2146335280 cites W2081055733 @default.
• W2146335280 cites W2085540330 @default.
• W2146335280 cites W2086369726 @default.
• W2146335280 cites W2086679183 @default.
• W2146335280 cites W2089154372 @default.
• W2146335280 cites W2096188040 @default.
• W2146335280 cites W2097119232 @default.
• W2146335280 cites W2099826167 @default.
• W2146335280 cites W2100181114 @default.
• W2146335280 cites W2113060990 @default.
• W2146335280 cites W2128421163 @default.
• W2146335280 cites W2139491529 @default.
• W2146335280 cites W2163186318 @default.
• W2146335280 cites W2163407551 @default.
• W2146335280 cites W2271388588 @default.
• W2146335280 cites W2278691802 @default.
• W2146335280 cites W2407228341 @default.
• W2146335280 cites W2412203566 @default.
• W2146335280 cites W2424723947 @default.
• W2146335280 cites W93254315 @default.
• W2146335280 doi "https://doi.org/10.1111/j.1537-2995.2007.01549.x" @default.
• W2146335280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18067507" @default.
• W2146335280 hasPublicationYear "2008" @default.
• W2146335280 type Work @default.
• W2146335280 sameAs 2146335280 @default.
• W2146335280 citedByCount "137" @default.
• W2146335280 countsByYear W21463352802012 @default.
• W2146335280 countsByYear W21463352802013 @default.
• W2146335280 countsByYear W21463352802014 @default.
• W2146335280 countsByYear W21463352802015 @default.
• W2146335280 countsByYear W21463352802016 @default.
• W2146335280 countsByYear W21463352802017 @default.
• W2146335280 countsByYear W21463352802018 @default.
• W2146335280 countsByYear W21463352802019 @default.
• W2146335280 countsByYear W21463352802020 @default.
• W2146335280 countsByYear W21463352802021 @default.
• W2146335280 countsByYear W21463352802022 @default.
• W2146335280 countsByYear W21463352802023 @default.
• W2146335280 crossrefType "journal-article" @default.
• W2146335280 hasAuthorship W2146335280A5002494487 @default.
• W2146335280 hasAuthorship W2146335280A5007608468 @default.
• W2146335280 hasAuthorship W2146335280A5011017158 @default.
• W2146335280 hasAuthorship W2146335280A5017035150 @default.
• W2146335280 hasAuthorship W2146335280A5037494404 @default.

• next