FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146454678> ?p ?o ?g. }

• W2146454678 endingPage "101" @default.
• W2146454678 startingPage "93" @default.
• W2146454678 abstract "Olfactory neurons have the rare property of being replaced throughout life. Factors regulating different developmental stages of olfactory receptor neurons (ORNs) are of great interest, because such factors might be used to extend regeneration in the post-developmental brain and spinal cord. Also, these factors may potentially be exploited to treat various smell disorders arising from changes in the olfactory epithelium. Characterization of trophic factors for ORNs requires cell culture systems that are simple and easy to manipulate. We have compared four different cell culture preparations, using two different enzymes and two different media to develop a simple culture system of olfactory epithelial cells. Our preferred preparation, which produces partially purified olfactory epithelial cultures, uses trypsin dissociation and a serum-free keratinocyte growth medium (KGM) supplemented with insulin. These conditions support ORN survival up to 1 week. They also supported other elements of the olfactory epithelium such as Bowman's gland cells and horizontal basal cells. Olfactory epithelial cells predominate, while contaminating mesenchymal cells (glia and fibroblasts) are present in low numbers. Using these cultures, it was determined that insulin was required for ORN survival in vitro. The simplicity of the epithelial cultures will be useful for further studies of insulin and other ORN trophic factors." @default.
• W2146454678 created "2016-06-24" @default.
• W2146454678 creator A5004175011 @default.
• W2146454678 creator A5007714019 @default.
• W2146454678 date "2000-02-01" @default.
• W2146454678 modified "2023-09-25" @default.
• W2146454678 title "Olfactory Receptor Neurons in Partially Purified Epithelial Cell Cultures: Comparison of Techniques for Partial Purification and Identification of Insulin as an Important Survival Factor" @default.
• W2146454678 cites W120093904 @default.
• W2146454678 cites W1521861864 @default.
• W2146454678 cites W1594700207 @default.
• W2146454678 cites W1678001779 @default.
• W2146454678 cites W1765469392 @default.
• W2146454678 cites W1876814577 @default.
• W2146454678 cites W1964908817 @default.
• W2146454678 cites W1966410619 @default.
• W2146454678 cites W1966792643 @default.
• W2146454678 cites W1970147140 @default.
• W2146454678 cites W1971977794 @default.
• W2146454678 cites W1975781078 @default.
• W2146454678 cites W1980398120 @default.
• W2146454678 cites W1985717414 @default.
• W2146454678 cites W1992559178 @default.
• W2146454678 cites W2004836530 @default.
• W2146454678 cites W2022310489 @default.
• W2146454678 cites W2030172814 @default.
• W2146454678 cites W2030951227 @default.
• W2146454678 cites W2033826557 @default.
• W2146454678 cites W2034115670 @default.
• W2146454678 cites W2035108601 @default.
• W2146454678 cites W2039119477 @default.
• W2146454678 cites W2039857019 @default.
• W2146454678 cites W2040893207 @default.
• W2146454678 cites W2070897110 @default.
• W2146454678 cites W2071198661 @default.
• W2146454678 cites W2082235150 @default.
• W2146454678 cites W2094807512 @default.
• W2146454678 cites W2109210857 @default.
• W2146454678 cites W2112634688 @default.
• W2146454678 cites W569951484 @default.
• W2146454678 doi "https://doi.org/10.1093/chemse/25.1.93" @default.
• W2146454678 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10667999" @default.
• W2146454678 hasPublicationYear "2000" @default.
• W2146454678 type Work @default.
• W2146454678 sameAs 2146454678 @default.
• W2146454678 citedByCount "21" @default.
• W2146454678 countsByYear W21464546782012 @default.
• W2146454678 countsByYear W21464546782015 @default.
• W2146454678 countsByYear W21464546782016 @default.
• W2146454678 countsByYear W21464546782017 @default.
• W2146454678 countsByYear W21464546782018 @default.
• W2146454678 countsByYear W21464546782020 @default.
• W2146454678 countsByYear W21464546782021 @default.
• W2146454678 crossrefType "journal-article" @default.
• W2146454678 hasAuthorship W2146454678A5004175011 @default.
• W2146454678 hasAuthorship W2146454678A5007714019 @default.
• W2146454678 hasBestOaLocation W21464546781 @default.
• W2146454678 hasConcept C134018914 @default.
• W2146454678 hasConcept C154988683 @default.
• W2146454678 hasConcept C169760540 @default.
• W2146454678 hasConcept C170493617 @default.
• W2146454678 hasConcept C201792869 @default.
• W2146454678 hasConcept C2779404012 @default.
• W2146454678 hasConcept C2779980732 @default.
• W2146454678 hasConcept C2780187430 @default.
• W2146454678 hasConcept C2780496858 @default.
• W2146454678 hasConcept C2781377823 @default.
• W2146454678 hasConcept C529278444 @default.
• W2146454678 hasConcept C529295009 @default.
• W2146454678 hasConcept C54355233 @default.
• W2146454678 hasConcept C55493867 @default.
• W2146454678 hasConcept C81885089 @default.
• W2146454678 hasConcept C86803240 @default.
• W2146454678 hasConcept C95444343 @default.
• W2146454678 hasConceptScore W2146454678C134018914 @default.
• W2146454678 hasConceptScore W2146454678C154988683 @default.
• W2146454678 hasConceptScore W2146454678C169760540 @default.
• W2146454678 hasConceptScore W2146454678C170493617 @default.
• W2146454678 hasConceptScore W2146454678C201792869 @default.
• W2146454678 hasConceptScore W2146454678C2779404012 @default.
• W2146454678 hasConceptScore W2146454678C2779980732 @default.
• W2146454678 hasConceptScore W2146454678C2780187430 @default.
• W2146454678 hasConceptScore W2146454678C2780496858 @default.
• W2146454678 hasConceptScore W2146454678C2781377823 @default.
• W2146454678 hasConceptScore W2146454678C529278444 @default.
• W2146454678 hasConceptScore W2146454678C529295009 @default.
• W2146454678 hasConceptScore W2146454678C54355233 @default.
• W2146454678 hasConceptScore W2146454678C55493867 @default.
• W2146454678 hasConceptScore W2146454678C81885089 @default.
• W2146454678 hasConceptScore W2146454678C86803240 @default.
• W2146454678 hasConceptScore W2146454678C95444343 @default.
• W2146454678 hasIssue "1" @default.
• W2146454678 hasLocation W21464546781 @default.
• W2146454678 hasLocation W21464546782 @default.
• W2146454678 hasOpenAccess W2146454678 @default.
• W2146454678 hasPrimaryLocation W21464546781 @default.
• W2146454678 hasRelatedWork W1968225758 @default.
• W2146454678 hasRelatedWork W1979288672 @default.
• W2146454678 hasRelatedWork W1997380868 @default.

• next