FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146455641> ?p ?o ?g. }

• W2146455641 endingPage "1478" @default.
• W2146455641 startingPage "1470" @default.
• W2146455641 abstract "Objective: The goal of this study was to investigate the complications and control of warfarin treatment in patients with nonvalvular atrial fibrillation (NVAF) newly referred to an outpatient anticoagulation clinic. Methods: This study included new patients with NVAF who were referred to an anticoagulation clinic for warfarin therapy over a recruitment period of 21 months. To reflect real-world clinical practice, patient selection for anticoagulation and patient management were left to the referring physicians, who were blinded to their patients' participation in the study. Patients were interviewed in person at the first clinic visit and then by telephone every 4 to 6 weeks. They were questioned about any bleeding or thromboembolic events. Results: A total of 402 patients were included (100% of all new referrals over 21 months). The mean (SD) age was 72.3 (10.3) years, and 224 (56%) patients were men. The mean (SD) international normalized ratio (INR) was 2.4 (0.31). Patients were followed up for a mean (SD) of 19 (8.1) months (range, 1.0–31.0 months). They spent a mean (SD) 66% (18.3) of time in the target range of INR (ie, 2.0–3.0). Annual event rates were 1.7% (95% CI, 0.4%–3.0%) for major bleeding, 16.6% (95% CI, 13.0%–20.2%) for minor bleeding, 1.2% (95% CI, 0.1%–2.3%) for ischemic stroke, and 0.3% (95% CI, 0.2%–0.8%) for transient ischemic attacks. There were no cases of hemorrhagic stroke or fatal bleeding. Variability of INR and number of medications were identified as risk factors for bleeding (P = 0.03 and P = 0.001, respectively). There was no significant association between age and bleeding. Conclusions: Based on this analysis, the risks of long-term oral anticoagulation therapy in an outpatient anticoagulation clinic appear to reflect the results of clinical trials. Rates of ischemic stroke, major bleeding, and anticoagulation control were comparable. There was no age-related risk of complications." @default.
• W2146455641 created "2016-06-24" @default.
• W2146455641 creator A5005063316 @default.
• W2146455641 creator A5039778206 @default.
• W2146455641 date "2004-09-01" @default.
• W2146455641 modified "2023-09-25" @default.
• W2146455641 title "Results of an open-label, prospective study of anticoagulant therapy for atrial fibrillation in an outpatient anticoagulation clinic" @default.
• W2146455641 cites W1586488555 @default.
• W2146455641 cites W1970659765 @default.
• W2146455641 cites W1978313703 @default.
• W2146455641 cites W1979993450 @default.
• W2146455641 cites W1981303513 @default.
• W2146455641 cites W1992857447 @default.
• W2146455641 cites W2001411232 @default.
• W2146455641 cites W2001473873 @default.
• W2146455641 cites W2005852096 @default.
• W2146455641 cites W2007303097 @default.
• W2146455641 cites W2021104859 @default.
• W2146455641 cites W2029345778 @default.
• W2146455641 cites W2030262988 @default.
• W2146455641 cites W2055663889 @default.
• W2146455641 cites W2069727389 @default.
• W2146455641 cites W2087739564 @default.
• W2146455641 cites W2109780115 @default.
• W2146455641 cites W2114048033 @default.
• W2146455641 cites W2127188103 @default.
• W2146455641 cites W2144407348 @default.
• W2146455641 cites W2283740320 @default.
• W2146455641 cites W2397305730 @default.
• W2146455641 cites W2499224120 @default.
• W2146455641 cites W96077822 @default.
• W2146455641 cites W2478411994 @default.
• W2146455641 doi "https://doi.org/10.1016/j.clinthera.2004.09.002" @default.
• W2146455641 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15531009" @default.
• W2146455641 hasPublicationYear "2004" @default.
• W2146455641 type Work @default.
• W2146455641 sameAs 2146455641 @default.
• W2146455641 citedByCount "52" @default.
• W2146455641 countsByYear W21464556412012 @default.
• W2146455641 countsByYear W21464556412013 @default.
• W2146455641 countsByYear W21464556412014 @default.
• W2146455641 countsByYear W21464556412015 @default.
• W2146455641 countsByYear W21464556412017 @default.
• W2146455641 countsByYear W21464556412018 @default.
• W2146455641 countsByYear W21464556412021 @default.
• W2146455641 countsByYear W21464556412023 @default.
• W2146455641 crossrefType "journal-article" @default.
• W2146455641 hasAuthorship W2146455641A5005063316 @default.
• W2146455641 hasAuthorship W2146455641A5039778206 @default.
• W2146455641 hasConcept C126322002 @default.
• W2146455641 hasConcept C127413603 @default.
• W2146455641 hasConcept C187212893 @default.
• W2146455641 hasConcept C188816634 @default.
• W2146455641 hasConcept C2776301958 @default.
• W2146455641 hasConcept C2778205648 @default.
• W2146455641 hasConcept C2779161974 @default.
• W2146455641 hasConcept C2780645631 @default.
• W2146455641 hasConcept C3017811039 @default.
• W2146455641 hasConcept C3020110884 @default.
• W2146455641 hasConcept C71924100 @default.
• W2146455641 hasConcept C78519656 @default.
• W2146455641 hasConceptScore W2146455641C126322002 @default.
• W2146455641 hasConceptScore W2146455641C127413603 @default.
• W2146455641 hasConceptScore W2146455641C187212893 @default.
• W2146455641 hasConceptScore W2146455641C188816634 @default.
• W2146455641 hasConceptScore W2146455641C2776301958 @default.
• W2146455641 hasConceptScore W2146455641C2778205648 @default.
• W2146455641 hasConceptScore W2146455641C2779161974 @default.
• W2146455641 hasConceptScore W2146455641C2780645631 @default.
• W2146455641 hasConceptScore W2146455641C3017811039 @default.
• W2146455641 hasConceptScore W2146455641C3020110884 @default.
• W2146455641 hasConceptScore W2146455641C71924100 @default.
• W2146455641 hasConceptScore W2146455641C78519656 @default.
• W2146455641 hasIssue "9" @default.
• W2146455641 hasLocation W21464556411 @default.
• W2146455641 hasLocation W21464556412 @default.
• W2146455641 hasOpenAccess W2146455641 @default.
• W2146455641 hasPrimaryLocation W21464556411 @default.
• W2146455641 hasRelatedWork W1983415041 @default.
• W2146455641 hasRelatedWork W2003235938 @default.
• W2146455641 hasRelatedWork W2063827826 @default.
• W2146455641 hasRelatedWork W2146455641 @default.
• W2146455641 hasRelatedWork W2404121944 @default.
• W2146455641 hasRelatedWork W2412888031 @default.
• W2146455641 hasRelatedWork W2896204226 @default.
• W2146455641 hasRelatedWork W3037829263 @default.
• W2146455641 hasRelatedWork W3193900294 @default.
• W2146455641 hasRelatedWork W4281914020 @default.
• W2146455641 hasVolume "26" @default.
• W2146455641 isParatext "false" @default.
• W2146455641 isRetracted "false" @default.
• W2146455641 magId "2146455641" @default.
• W2146455641 workType "article" @default.