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• W2146457986 abstract "Objective: To investigate a possible deficit of the voluntary movement mechanism within the central nervous system (CNS) in patients with myotonic dystrophy (MyD). Methods: Movement-related cortical potentials preceding voluntary extension of the right middle and index fingers were studied in 9 patients with MyD and compared with those in 11 age-matched healthy subjects and 9 age-matched patients with other neuromuscular disorders (NMDs). Results: The amplitudes of Bereitschaftspotential was smaller in MyD patients than in age-matched controls and age-matched patients with other NMDs although there was no statistically significant difference. The amplitude of negative slope was significantly smaller in MyD patients than in age-matched controls and age-matched patients with other NMDs. Clinical findings such as age, disease duration, degree of motor impairment and cognitive function had no effect on the individual electrophysiological parameters. Conclusions: The present results suggest that subclinical abnormalities exist in CNS function associated with motor preparation and execution, which is independent of muscle weakness." @default.
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• W2146457986 date "2003-01-01" @default.
• W2146457986 modified "2023-10-14" @default.
• W2146457986 title "Movement-related cortical potentials in myotonic dystrophy" @default.
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• W2146457986 doi "https://doi.org/10.1016/s1388-2457(02)00325-5" @default.
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