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• W2146476667 abstract "Abstract Background Anorectal manometry with simulated evacuation ( SE ) has limited applicability in predicting balloon expulsion ( BE ) test results. The newly developed high‐resolution anorectal manometry ( HRAM ) technique can yield spatiotemporal plots with three‐dimensional pressurization. We aimed to define new parameters based on three‐dimensional integrated pressurized volume ( IPV ) for predicting the BE test results in asymptomatic normal individuals. Methods Fifty‐four asymptomatic healthy individuals were prospectively enrolled. BE tests were performed using 50 mL of water, and a requirement of more than 1 min was considered as delayed BE . HRAM profiles were converted into ASCII files and analyzed using a MATLAB program. A three‐dimensional IPV was plotted after transforming the data to a cubic spline interpolation followed by resampling the manometry position at 0.1‐cm intervals. Key Results Eight of the 54 (15%) individuals demonstrated delayed BE . Conventional manometric profiles did not differ significantly between cases of early and delayed BE . Receiver‐operator characteristic curve analysis revealed that the ratio of the IPV s of the upper 1 cm to the lower 4 cm of the anorectal canal with balloon distension was more predictable of the BE results (area under curve, 0.73: 95% confidence interval, 0.53–0.92; p = 0.04) than the other IPV s or their ratios. Conclusions & Inferences The newly developed IPV methods could predict delayed BE tests during SE better than the conventional parameters defined on the basis of linear waves. Well‐designed prospective trials on a large number of subjects are warranted to validate the clinical application of this novel parameter." @default.
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• W2146476667 date "2014-04-23" @default.
• W2146476667 modified "2023-10-06" @default.
• W2146476667 title "A novel high-resolution anorectal manometry parameter based on a three-dimensional integrated pressurized volume of a spatiotemporal plot, for predicting balloon expulsion in asymptomatic normal individuals" @default.
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• W2146476667 doi "https://doi.org/10.1111/nmo.12347" @default.
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