FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146602240> ?p ?o ?g. }

• W2146602240 endingPage "350" @default.
• W2146602240 startingPage "343" @default.
• W2146602240 abstract "Extract of Adhatoda vasica (L) Nees leaves has been used for treatment of various diseases and disorders in Ayurved and Unani medicine. Modulatory effect of ethanolic extract of A. vasica (L) Nees against radiation-induced changes in terms of histological alterations in testis, reduced glutathione (GSH), lipid peroxidation (LPO), acid and alkaline phosphatases levels, and chromosomal alterations in Swiss albino mice was studied at various post-irradiation intervals between 1 and 30 days. Mice exposed to 8 Gy radiation showed radiation-induced sickness including marked changes in histology of testis and chromosomal aberrations in bone marrow cells with 100% mortality within 22 days. When ethanolic leaf extract of A. vasica was given orally at a dose of 800 mg kg(-1) body weight per mouse for 15 consecutive days and then exposed to radiation, death of Adhatoda-pretreated irradiated mice was reduced to 70% at 30 days. The radiation dose reduction factor was 1.43. There was significantly lesser degree of damage to testis tissue architecture and various cell populations including spermatogonia, spermatids and Leydig cells. Correspondingly, a significant decrease in the LPO and an increase in the GSH levels were observed in testis and liver of Adhatoda-pretreated irradiated mice. Similarly, a significant decrease in level of acid phosphatase and increase in level of alkaline phosphatase were observed. Adhatoda pretreatment significantly prevented radiation-induced chromosomal damage in bone marrow cells. The study suggests that Adhatoda plant extract has significant radioprotective effects on testis that warrants further mechanistic studies aimed at identifying the role of major ingredients in the extract." @default.
• W2146602240 created "2016-06-24" @default.
• W2146602240 creator A5009084198 @default.
• W2146602240 creator A5054405938 @default.
• W2146602240 creator A5057436534 @default.
• W2146602240 creator A5070579300 @default.
• W2146602240 creator A5080318306 @default.
• W2146602240 creator A5081428706 @default.
• W2146602240 date "2007-01-01" @default.
• W2146602240 modified "2023-10-16" @default.
• W2146602240 title "Protective Effect of<i>Adhatoda vascia</i>Nees against Radiation-Induced Damage at Cellular, Biochemical and Chromosomal Levels in Swiss Albino Mice" @default.
• W2146602240 cites W101261839 @default.
• W2146602240 cites W101803590 @default.
• W2146602240 cites W107654206 @default.
• W2146602240 cites W121154313 @default.
• W2146602240 cites W1647598887 @default.
• W2146602240 cites W171146783 @default.
• W2146602240 cites W1925715381 @default.
• W2146602240 cites W1983310681 @default.
• W2146602240 cites W1989346745 @default.
• W2146602240 cites W1990321447 @default.
• W2146602240 cites W2001786662 @default.
• W2146602240 cites W2007350044 @default.
• W2146602240 cites W2009344005 @default.
• W2146602240 cites W2040670862 @default.
• W2146602240 cites W2051658124 @default.
• W2146602240 cites W2053696425 @default.
• W2146602240 cites W2064219510 @default.
• W2146602240 cites W2069132215 @default.
• W2146602240 cites W2070850441 @default.
• W2146602240 cites W2080568589 @default.
• W2146602240 cites W2081623392 @default.
• W2146602240 cites W2089725130 @default.
• W2146602240 cites W2101339056 @default.
• W2146602240 cites W2114691179 @default.
• W2146602240 cites W2123569076 @default.
• W2146602240 cites W2134842491 @default.
• W2146602240 cites W2139038573 @default.
• W2146602240 cites W2152626360 @default.
• W2146602240 cites W2153435210 @default.
• W2146602240 cites W2186942424 @default.
• W2146602240 cites W2396997251 @default.
• W2146602240 cites W2410086449 @default.
• W2146602240 doi "https://doi.org/10.1093/ecam/nel098" @default.
• W2146602240 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1978234" @default.
• W2146602240 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17965765" @default.
• W2146602240 hasPublicationYear "2007" @default.
• W2146602240 type Work @default.
• W2146602240 sameAs 2146602240 @default.
• W2146602240 citedByCount "27" @default.
• W2146602240 countsByYear W21466022402012 @default.
• W2146602240 countsByYear W21466022402013 @default.
• W2146602240 countsByYear W21466022402014 @default.
• W2146602240 countsByYear W21466022402015 @default.
• W2146602240 countsByYear W21466022402016 @default.
• W2146602240 countsByYear W21466022402017 @default.
• W2146602240 countsByYear W21466022402018 @default.
• W2146602240 countsByYear W21466022402020 @default.
• W2146602240 countsByYear W21466022402021 @default.
• W2146602240 countsByYear W21466022402022 @default.
• W2146602240 countsByYear W21466022402023 @default.
• W2146602240 crossrefType "journal-article" @default.
• W2146602240 hasAuthorship W2146602240A5009084198 @default.
• W2146602240 hasAuthorship W2146602240A5054405938 @default.
• W2146602240 hasAuthorship W2146602240A5057436534 @default.
• W2146602240 hasAuthorship W2146602240A5070579300 @default.
• W2146602240 hasAuthorship W2146602240A5080318306 @default.
• W2146602240 hasAuthorship W2146602240A5081428706 @default.
• W2146602240 hasBestOaLocation W21466022401 @default.
• W2146602240 hasConcept C126322002 @default.
• W2146602240 hasConcept C134018914 @default.
• W2146602240 hasConcept C160160445 @default.
• W2146602240 hasConcept C16685009 @default.
• W2146602240 hasConcept C181199279 @default.
• W2146602240 hasConcept C185592680 @default.
• W2146602240 hasConcept C203014093 @default.
• W2146602240 hasConcept C21547065 @default.
• W2146602240 hasConcept C2776151105 @default.
• W2146602240 hasConcept C2780007613 @default.
• W2146602240 hasConcept C2780829032 @default.
• W2146602240 hasConcept C538909803 @default.
• W2146602240 hasConcept C55493867 @default.
• W2146602240 hasConcept C71924100 @default.
• W2146602240 hasConcept C86803240 @default.
• W2146602240 hasConcept C98274493 @default.
• W2146602240 hasConceptScore W2146602240C126322002 @default.
• W2146602240 hasConceptScore W2146602240C134018914 @default.
• W2146602240 hasConceptScore W2146602240C160160445 @default.
• W2146602240 hasConceptScore W2146602240C16685009 @default.
• W2146602240 hasConceptScore W2146602240C181199279 @default.
• W2146602240 hasConceptScore W2146602240C185592680 @default.
• W2146602240 hasConceptScore W2146602240C203014093 @default.
• W2146602240 hasConceptScore W2146602240C21547065 @default.
• W2146602240 hasConceptScore W2146602240C2776151105 @default.
• W2146602240 hasConceptScore W2146602240C2780007613 @default.
• W2146602240 hasConceptScore W2146602240C2780829032 @default.
• W2146602240 hasConceptScore W2146602240C538909803 @default.
• W2146602240 hasConceptScore W2146602240C55493867 @default.

• next