FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146647072> ?p ?o ?g. }

• W2146647072 endingPage "178" @default.
• W2146647072 startingPage "168" @default.
• W2146647072 abstract "Although nerve conduction slowing is a well-accepted abnormality in rats with acute experimental diabetes, reports of neuropathological changes in diabetic rat nerves have been inconsistent. To examine this further, we studied electrophysiological and morphological features of posterior tibial nerves and their distal branches from four-week streptozotocin-induced diabetic rats and matched controls. Diabetic rat posterior tibial motor conduction was slowed (mean +/- 1 SD, 34.8 +/- 3.1 m/sec; controls, 41.2 +/- 2.5 m/sec), and evoked muscle response amplitudes were only half of control values. Using quantitative techniques, we documented a diminution in number of the largest myelinated fibers in otherwise normal mid posterior tibial nerves, with an increase in the smaller sizes, indicating either a degree of axonal atrophy or impaired fiber growth during development. The principal pathological finding was active breakdown of myelinated fibers in the most distal motor twigs of hindfoot muscles supplied by posterior tibial branches, with preservation of fibers in more proximal segments of these nerves. This anatomical lesion in diabetic nerves could account for both oberved conduction slowing and lowered muscle response amplitudes. A consistent feature in both diabetic and control mid lateral plantar nerves was a zone of demyelination that apparently occurs at this natural site of nerve entrapment in rats. Taken together, the pathological abnormalities of peripheral nerve in acute experimental diabetes are best explained as resulting from a distal axonopathy." @default.
• W2146647072 created "2016-06-24" @default.
• W2146647072 creator A5002664705 @default.
• W2146647072 creator A5043034950 @default.
• W2146647072 creator A5054866577 @default.
• W2146647072 creator A5062436495 @default.
• W2146647072 creator A5077875903 @default.
• W2146647072 date "1980-08-01" @default.
• W2146647072 modified "2023-10-16" @default.
• W2146647072 title "Distal neuropathy in experimental diabetes mellitus" @default.
• W2146647072 cites W1989839330 @default.
• W2146647072 cites W1996884513 @default.
• W2146647072 cites W2002032785 @default.
• W2146647072 cites W2006845012 @default.
• W2146647072 cites W2007676657 @default.
• W2146647072 cites W2008985008 @default.
• W2146647072 cites W2014179570 @default.
• W2146647072 cites W2014888260 @default.
• W2146647072 cites W2017864290 @default.
• W2146647072 cites W2021518397 @default.
• W2146647072 cites W2022411713 @default.
• W2146647072 cites W2022818675 @default.
• W2146647072 cites W2033496166 @default.
• W2146647072 cites W2041582826 @default.
• W2146647072 cites W2045055708 @default.
• W2146647072 cites W2049803451 @default.
• W2146647072 cites W2052243849 @default.
• W2146647072 cites W2057404074 @default.
• W2146647072 cites W2065299718 @default.
• W2146647072 cites W2065510596 @default.
• W2146647072 cites W2070902451 @default.
• W2146647072 cites W2073936254 @default.
• W2146647072 cites W2082053843 @default.
• W2146647072 cites W2083114211 @default.
• W2146647072 cites W2083894334 @default.
• W2146647072 cites W2087366329 @default.
• W2146647072 cites W2088766638 @default.
• W2146647072 cites W2093957781 @default.
• W2146647072 cites W2103323770 @default.
• W2146647072 cites W2122054430 @default.
• W2146647072 cites W2127944449 @default.
• W2146647072 cites W2139704483 @default.
• W2146647072 cites W2143655681 @default.
• W2146647072 cites W2157339829 @default.
• W2146647072 cites W2167935718 @default.
• W2146647072 cites W2324357427 @default.
• W2146647072 cites W2328813842 @default.
• W2146647072 cites W2333863178 @default.
• W2146647072 cites W2784346295 @default.
• W2146647072 cites W4234692840 @default.
• W2146647072 cites W4253181244 @default.
• W2146647072 doi "https://doi.org/10.1002/ana.410080207" @default.
• W2146647072 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7425570" @default.
• W2146647072 hasPublicationYear "1980" @default.
• W2146647072 type Work @default.
• W2146647072 sameAs 2146647072 @default.
• W2146647072 citedByCount "88" @default.
• W2146647072 countsByYear W21466470722012 @default.
• W2146647072 countsByYear W21466470722014 @default.
• W2146647072 countsByYear W21466470722015 @default.
• W2146647072 countsByYear W21466470722016 @default.
• W2146647072 countsByYear W21466470722018 @default.
• W2146647072 crossrefType "journal-article" @default.
• W2146647072 hasAuthorship W2146647072A5002664705 @default.
• W2146647072 hasAuthorship W2146647072A5043034950 @default.
• W2146647072 hasAuthorship W2146647072A5054866577 @default.
• W2146647072 hasAuthorship W2146647072A5062436495 @default.
• W2146647072 hasAuthorship W2146647072A5077875903 @default.
• W2146647072 hasConcept C105702510 @default.
• W2146647072 hasConcept C118552586 @default.
• W2146647072 hasConcept C126322002 @default.
• W2146647072 hasConcept C134018914 @default.
• W2146647072 hasConcept C142724271 @default.
• W2146647072 hasConcept C179253579 @default.
• W2146647072 hasConcept C185263204 @default.
• W2146647072 hasConcept C207886595 @default.
• W2146647072 hasConcept C24998067 @default.
• W2146647072 hasConcept C2776825438 @default.
• W2146647072 hasConcept C2779178840 @default.
• W2146647072 hasConcept C2779901536 @default.
• W2146647072 hasConcept C2781156865 @default.
• W2146647072 hasConcept C2781172350 @default.
• W2146647072 hasConcept C46762472 @default.
• W2146647072 hasConcept C50965678 @default.
• W2146647072 hasConcept C555293320 @default.
• W2146647072 hasConcept C71924100 @default.
• W2146647072 hasConceptScore W2146647072C105702510 @default.
• W2146647072 hasConceptScore W2146647072C118552586 @default.
• W2146647072 hasConceptScore W2146647072C126322002 @default.
• W2146647072 hasConceptScore W2146647072C134018914 @default.
• W2146647072 hasConceptScore W2146647072C142724271 @default.
• W2146647072 hasConceptScore W2146647072C179253579 @default.
• W2146647072 hasConceptScore W2146647072C185263204 @default.
• W2146647072 hasConceptScore W2146647072C207886595 @default.
• W2146647072 hasConceptScore W2146647072C24998067 @default.
• W2146647072 hasConceptScore W2146647072C2776825438 @default.
• W2146647072 hasConceptScore W2146647072C2779178840 @default.
• W2146647072 hasConceptScore W2146647072C2779901536 @default.

• next