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• W2146660490 endingPage "258" @default.
• W2146660490 startingPage "249" @default.
• W2146660490 abstract "The development of clozapine was thought to herald a new era of antipsychotic drug treatment by virtue of increased efficacy and fewer motor side effects. However, its non-motor side effects undermined its utility. We will argue that with the exception of quetiapine and clozapine, the other members of the ‘atypical antipsychotics’ have significant motor side effects, and that these side effects differ from drug to drug. All of the other compounds cause parkinsonism and worsen motor function in people with parkinsonian syndromes. Some are more likely than others to cause either acute dystonic reactions or akathisia. Only risperidone has so far been clearly linked as a cause of tardive dyskinesia when used long-term in neuroleptic-naive patients, but this lack of association may be due only to limitations in data collection. All of the atypical antipsychotics, including quetiapine and clozapine, have been convincingly reported to cause neuroleptic malignant syndrome." @default.
• W2146660490 created "2016-06-24" @default.
• W2146660490 creator A5022553846 @default.
• W2146660490 creator A5049026478 @default.
• W2146660490 date "2009-03-01" @default.
• W2146660490 modified "2023-10-18" @default.
• W2146660490 title "Motor side effects of atypical antipsychotic drugs" @default.
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