FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146702986> ?p ?o ?g. }

• W2146702986 endingPage "211" @default.
• W2146702986 startingPage "203" @default.
• W2146702986 abstract "Protein restriction and hypercalcemia result in a urinary concentrating defect in rats and humans. Previous tubular perfusion studies show that there is an increased active urea transport activity in the initial inner medullary (IM) collecting duct in low-protein diet (LPD) and vitamin D (Vit D) animal models. To investigate the possible mechanisms that cause the urinary concentrating defect and to clone the new active urea transporter, we employed a modified two-tester suppression subtractive hybridization (ttSSH) approach and examined gene expression induced by LPD and Vit D in kidney IM base. Approximately 600 clones from the subtracted library were randomly selected; 150 clones were further confirmed to be the true positive genes by slot blot hybridization with subtracted probes from LPD and Vit D and sent for DNA sequencing. We identified 10 channel/transporter genes that were upregulated in IM base in LPD and Vit D animal models; 8 were confirmed by real-time PCR. These genes include aquaporin 2 (AQP2), two-pore calcium channel protein 2, brain-specific organic cation transporter, Na + - and H + -coupled glutamine transporter, and solute carrier family 25. Nine genes are totally new, and twelve are uncharacterized hypothetical proteins. Among them, four genes were shown to be new transmembrane proteins as judged by Kyte-Doolittle hydrophobic plot analysis. ttSSH provides a useful method to identify new genes from two conditioned populations." @default.
• W2146702986 created "2016-06-24" @default.
• W2146702986 creator A5014014770 @default.
• W2146702986 creator A5023732082 @default.
• W2146702986 creator A5055516364 @default.
• W2146702986 creator A5061722289 @default.
• W2146702986 creator A5066353889 @default.
• W2146702986 date "2010-05-01" @default.
• W2146702986 modified "2023-10-15" @default.
• W2146702986 title "Suppression subtractive hybridization analysis of low-protein diet- and vitamin D-induced gene expression from rat kidney inner medullary base" @default.
• W2146702986 cites W1968683511 @default.
• W2146702986 cites W1973165097 @default.
• W2146702986 cites W1976372374 @default.
• W2146702986 cites W1978665561 @default.
• W2146702986 cites W1983890412 @default.
• W2146702986 cites W1987442187 @default.
• W2146702986 cites W1994163115 @default.
• W2146702986 cites W2003369977 @default.
• W2146702986 cites W2007078941 @default.
• W2146702986 cites W2012617920 @default.
• W2146702986 cites W2018670548 @default.
• W2146702986 cites W2018779154 @default.
• W2146702986 cites W2024187587 @default.
• W2146702986 cites W2031790758 @default.
• W2146702986 cites W2032369929 @default.
• W2146702986 cites W2071985581 @default.
• W2146702986 cites W2076216028 @default.
• W2146702986 cites W2084158810 @default.
• W2146702986 cites W2084356001 @default.
• W2146702986 cites W2085377722 @default.
• W2146702986 cites W2087550577 @default.
• W2146702986 cites W2091703464 @default.
• W2146702986 cites W2093833153 @default.
• W2146702986 cites W2108318326 @default.
• W2146702986 cites W2114078055 @default.
• W2146702986 cites W2120285739 @default.
• W2146702986 cites W2120603812 @default.
• W2146702986 cites W2122209825 @default.
• W2146702986 cites W2125244822 @default.
• W2146702986 cites W2134818464 @default.
• W2146702986 cites W2144295254 @default.
• W2146702986 cites W2146643220 @default.
• W2146702986 cites W2146739117 @default.
• W2146702986 cites W2163685751 @default.
• W2146702986 cites W2254367910 @default.
• W2146702986 cites W2258090097 @default.
• W2146702986 cites W2339225184 @default.
• W2146702986 cites W2417622984 @default.
• W2146702986 cites W2418228551 @default.
• W2146702986 cites W2472597017 @default.
• W2146702986 doi "https://doi.org/10.1152/physiolgenomics.00129.2009" @default.
• W2146702986 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2869109" @default.
• W2146702986 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20197420" @default.
• W2146702986 hasPublicationYear "2010" @default.
• W2146702986 type Work @default.
• W2146702986 sameAs 2146702986 @default.
• W2146702986 citedByCount "5" @default.
• W2146702986 countsByYear W21467029862014 @default.
• W2146702986 countsByYear W21467029862015 @default.
• W2146702986 countsByYear W21467029862017 @default.
• W2146702986 countsByYear W21467029862018 @default.
• W2146702986 crossrefType "journal-article" @default.
• W2146702986 hasAuthorship W2146702986A5014014770 @default.
• W2146702986 hasAuthorship W2146702986A5023732082 @default.
• W2146702986 hasAuthorship W2146702986A5055516364 @default.
• W2146702986 hasAuthorship W2146702986A5061722289 @default.
• W2146702986 hasAuthorship W2146702986A5066353889 @default.
• W2146702986 hasBestOaLocation W21467029862 @default.
• W2146702986 hasConcept C104317684 @default.
• W2146702986 hasConcept C149011108 @default.
• W2146702986 hasConcept C150194340 @default.
• W2146702986 hasConcept C153911025 @default.
• W2146702986 hasConcept C154280991 @default.
• W2146702986 hasConcept C168785527 @default.
• W2146702986 hasConcept C177707886 @default.
• W2146702986 hasConcept C189482833 @default.
• W2146702986 hasConcept C196436469 @default.
• W2146702986 hasConcept C55493867 @default.
• W2146702986 hasConcept C86803240 @default.
• W2146702986 hasConceptScore W2146702986C104317684 @default.
• W2146702986 hasConceptScore W2146702986C149011108 @default.
• W2146702986 hasConceptScore W2146702986C150194340 @default.
• W2146702986 hasConceptScore W2146702986C153911025 @default.
• W2146702986 hasConceptScore W2146702986C154280991 @default.
• W2146702986 hasConceptScore W2146702986C168785527 @default.
• W2146702986 hasConceptScore W2146702986C177707886 @default.
• W2146702986 hasConceptScore W2146702986C189482833 @default.
• W2146702986 hasConceptScore W2146702986C196436469 @default.
• W2146702986 hasConceptScore W2146702986C55493867 @default.
• W2146702986 hasConceptScore W2146702986C86803240 @default.
• W2146702986 hasIssue "3" @default.
• W2146702986 hasLocation W21467029861 @default.
• W2146702986 hasLocation W21467029862 @default.
• W2146702986 hasLocation W21467029863 @default.
• W2146702986 hasLocation W21467029864 @default.
• W2146702986 hasOpenAccess W2146702986 @default.
• W2146702986 hasPrimaryLocation W21467029861 @default.
• W2146702986 hasRelatedWork W1546836915 @default.

• next