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- W2146714906 endingPage "27" @default.
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- W2146714906 abstract "With the high cost and the long-term assessment of developmental toxicity testing in mammals, the vertebrate zebrafish has become a useful alternative model organism for high-throughput developmental toxicity testing. Zebrafish is also very favorable for the 3R perspective in toxicology; however, the methodologies used by research groups vary greatly, posing considerable challenges to integrative analysis. In this review, we discuss zebrafish developmental toxicity testing, focusing on the methods of chemical exposure, the assessment of morphological abnormalities, housing conditions and their effects on the production of healthy embryos, and future directions. Zebrafish as a systems toxicology model has the potential to elucidate developmental toxicity pathways, and to provide a sound basis for human health risk assessments." @default.
- W2146714906 created "2016-06-24" @default.
- W2146714906 creator A5021763338 @default.
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- W2146714906 creator A5090154188 @default.
- W2146714906 date "2016-01-01" @default.
- W2146714906 modified "2023-10-09" @default.
- W2146714906 title "Using zebrafish in systems toxicology for developmental toxicity testing" @default.
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