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• W2146724246 abstract "—Rat pineal serotonin N—acetyltransferase activity increases 30–70-fold at night in the dark and then decreases rapidly when animals are exposed to light. Activity of the enzyme is also stimulated by l-norepinephrine in organ culture. When homogenates of glands stimulated by dark in vivo or NE in vitro are incubated at 37°C, enzyme activity will also rapidly decrease. This decrease can be prevented by one of the cosubstrates of the enzyme, acetyl–CoA. Protection can also be conferred by cysteamine (β-mercaptoethylamine, HS–CH2–CH2–NH2) which is the terminal portion of the CoA molecule. This protection mechanism could be involved in the physiological control of enzyme activity." @default.
• W2146724246 created "2016-06-24" @default.
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• W2146724246 date "1976-04-01" @default.
• W2146724246 modified "2023-10-16" @default.
• W2146724246 title "SUBCELLULAR DISTRIBUTION OF DOPAMINE-?-HYDROXYLASE AND INHIBITORS IN THE HIPPOCAMPUS AND CAUDATE NUCLEUS IN SHEEP BRAIN" @default.
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• W2146724246 doi "https://doi.org/10.1111/j.1471-4159.1976.tb04435.x" @default.
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