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- W2146729525 abstract "Polymorphonuclear neutrophils are the most important mammalian host defence cells against infections with Pseudomonas aeruginosa. Screening of a signature tagged mutagenesis library of the non-piliated P. aeruginosa strain TBCF10839 uncovered that transposon inactivation of its pilY1 gene rendered the bacterium more resistant against killing by neutrophils than the wild type and any other of the more than 3000 tested mutants. Inactivation of pilY1 led to the loss of twitching motility in twitching-proficient wild-type PA14 and PAO1 strains, predisposed to autolysis and impaired the secretion of quinolones and pyocyanin, but on the other hand promoted growth in stationary phase and bacterial survival in murine airway infection models. The PilY1 population consisted of a major full-length and a minor shorter PilY1* isoform. PilY1* was detectable in small extracellular quinolone-positive aggregates, but not in the pilus. P. aeruginosa PilY1 is not an adhesin on the pilus tip, but assists in pilus biogenesis, twitching motility, secretion of secondary metabolites and in the control of cell density in the bacterial population." @default.
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- W2146729525 date "2009-02-01" @default.
- W2146729525 modified "2023-09-27" @default.
- W2146729525 title "Multiple roles of<i>Pseudomonas aeruginosa</i>TBCF10839 PilY1 in motility, transport and infection" @default.
- W2146729525 cites W141823637 @default.
- W2146729525 cites W1603754669 @default.
- W2146729525 cites W179557453 @default.
- W2146729525 cites W1845147287 @default.
- W2146729525 cites W1964957585 @default.
- W2146729525 cites W1976891867 @default.
- W2146729525 cites W1978046264 @default.
- W2146729525 cites W1979699645 @default.
- W2146729525 cites W1983312260 @default.
- W2146729525 cites W1983439313 @default.
- W2146729525 cites W1986585175 @default.
- W2146729525 cites W1990754866 @default.
- W2146729525 cites W1992851320 @default.
- W2146729525 cites W1993381520 @default.
- W2146729525 cites W2000125435 @default.
- W2146729525 cites W2003489402 @default.
- W2146729525 cites W2005222994 @default.
- W2146729525 cites W2010230246 @default.
- W2146729525 cites W2012875995 @default.
- W2146729525 cites W2013740990 @default.
- W2146729525 cites W2016923855 @default.
- W2146729525 cites W2022255441 @default.
- W2146729525 cites W2027241702 @default.
- W2146729525 cites W2027442998 @default.
- W2146729525 cites W2027827171 @default.
- W2146729525 cites W2030463023 @default.
- W2146729525 cites W2030956160 @default.
- W2146729525 cites W2033193754 @default.
- W2146729525 cites W2033457495 @default.
- W2146729525 cites W2034242845 @default.
- W2146729525 cites W2036999399 @default.
- W2146729525 cites W2039696366 @default.
- W2146729525 cites W2040661576 @default.
- W2146729525 cites W2042759586 @default.
- W2146729525 cites W2050381177 @default.
- W2146729525 cites W2053095874 @default.
- W2146729525 cites W2060772988 @default.
- W2146729525 cites W2061010047 @default.
- W2146729525 cites W2064612941 @default.
- W2146729525 cites W2082730687 @default.
- W2146729525 cites W2083761792 @default.
- W2146729525 cites W2084879740 @default.
- W2146729525 cites W2086247605 @default.
- W2146729525 cites W2087371604 @default.
- W2146729525 cites W2088732289 @default.
- W2146729525 cites W2091990251 @default.
- W2146729525 cites W2095490214 @default.
- W2146729525 cites W2096121963 @default.
- W2146729525 cites W2098894017 @default.
- W2146729525 cites W2099895090 @default.
- W2146729525 cites W2100619015 @default.
- W2146729525 cites W2104268547 @default.
- W2146729525 cites W2112356793 @default.
- W2146729525 cites W2114423853 @default.
- W2146729525 cites W2121178227 @default.
- W2146729525 cites W2123273294 @default.
- W2146729525 cites W2126918333 @default.
- W2146729525 cites W2127186235 @default.
- W2146729525 cites W2133425351 @default.
- W2146729525 cites W2140535381 @default.
- W2146729525 cites W2142648753 @default.
- W2146729525 cites W2145182206 @default.
- W2146729525 cites W2149353640 @default.
- W2146729525 cites W2150417163 @default.
- W2146729525 cites W2150927592 @default.
- W2146729525 cites W2151923418 @default.
- W2146729525 cites W2152713128 @default.
- W2146729525 cites W2156728976 @default.
- W2146729525 cites W2166135736 @default.
- W2146729525 cites W2166294904 @default.
- W2146729525 cites W2168259678 @default.
- W2146729525 cites W4211158047 @default.
- W2146729525 cites W4240233279 @default.
- W2146729525 cites W4377077253 @default.
- W2146729525 doi "https://doi.org/10.1111/j.1365-2958.2008.06559.x" @default.