Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146789504> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2146789504 endingPage "499" @default.
- W2146789504 startingPage "499" @default.
- W2146789504 abstract "To test the feasibility of using the deaf white cat model of early-onset deafness. We studied the neuronal effects of prosthetic intervention with a clinical, off-the-shelf multichannel cochlear implant.We placed cochlear implants in 5 deaf white kittens at age 12 and 24 weeks. The devices were activated and stimulated in the laboratory using a clinical speech processor programmed with a high-resolution continuous interleaved sampling (CIS) strategy for 8 to 24 weeks. Stimulus parameters were guided by electrically evoked brainstem responses and intracochlear-evoked potentials. Kittens were assessed with respect to their tolerance and general behavior in response to speech, music, and environmental sounds.Surgical complications were minimal, and kittens tolerated the experimental procedures well. Subjects were able to detect and respond to a specific sound played from a computer speaker. Electrophysiologic responses were reliably attainable and showed consistency with observed behavioral responses to sound. This experimental paradigm, using clinical devices, can be used in a practical research setting in cats.Deafness and other variations in neural activity result in many distinct changes to the central auditory pathways. Animal models will facilitate assessment of the reversibility of deafness-associated changes at the level of the neuron and its connections. Our observations of the feasibility of using clinical devices in animal models will enable us to simulate clinical conditions in addressing questions about the effects of replacement activity on the structure and function within the central auditory pathways in deafness." @default.
- W2146789504 created "2016-06-24" @default.
- W2146789504 creator A5025987970 @default.
- W2146789504 creator A5041932200 @default.
- W2146789504 creator A5045347846 @default.
- W2146789504 creator A5061587537 @default.
- W2146789504 date "2004-05-01" @default.
- W2146789504 modified "2023-09-27" @default.
- W2146789504 title "An Animal Model for Cochlear Implants" @default.
- W2146789504 cites W1529049651 @default.
- W2146789504 cites W160147784 @default.
- W2146789504 cites W1610951755 @default.
- W2146789504 cites W1975618971 @default.
- W2146789504 cites W1978415644 @default.
- W2146789504 cites W1987734661 @default.
- W2146789504 cites W1995459135 @default.
- W2146789504 cites W2002497445 @default.
- W2146789504 cites W2007313561 @default.
- W2146789504 cites W2031831962 @default.
- W2146789504 cites W2067042668 @default.
- W2146789504 cites W2080033848 @default.
- W2146789504 cites W2092305659 @default.
- W2146789504 cites W2095010767 @default.
- W2146789504 cites W2103370854 @default.
- W2146789504 cites W2119218036 @default.
- W2146789504 cites W2141551057 @default.
- W2146789504 cites W2159667989 @default.
- W2146789504 cites W2167888872 @default.
- W2146789504 cites W2412349949 @default.
- W2146789504 cites W2472439824 @default.
- W2146789504 cites W3145662472 @default.
- W2146789504 doi "https://doi.org/10.1001/archotol.130.5.499" @default.
- W2146789504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15148168" @default.
- W2146789504 hasPublicationYear "2004" @default.
- W2146789504 type Work @default.
- W2146789504 sameAs 2146789504 @default.
- W2146789504 citedByCount "30" @default.
- W2146789504 countsByYear W21467895042012 @default.
- W2146789504 countsByYear W21467895042013 @default.
- W2146789504 countsByYear W21467895042014 @default.
- W2146789504 countsByYear W21467895042015 @default.
- W2146789504 countsByYear W21467895042016 @default.
- W2146789504 countsByYear W21467895042017 @default.
- W2146789504 countsByYear W21467895042018 @default.
- W2146789504 countsByYear W21467895042019 @default.
- W2146789504 countsByYear W21467895042022 @default.
- W2146789504 countsByYear W21467895042023 @default.
- W2146789504 crossrefType "journal-article" @default.
- W2146789504 hasAuthorship W2146789504A5025987970 @default.
- W2146789504 hasAuthorship W2146789504A5041932200 @default.
- W2146789504 hasAuthorship W2146789504A5045347846 @default.
- W2146789504 hasAuthorship W2146789504A5061587537 @default.
- W2146789504 hasBestOaLocation W21467895042 @default.
- W2146789504 hasConcept C134018914 @default.
- W2146789504 hasConcept C15744967 @default.
- W2146789504 hasConcept C169760540 @default.
- W2146789504 hasConcept C2778117688 @default.
- W2146789504 hasConcept C2778882171 @default.
- W2146789504 hasConcept C2779918689 @default.
- W2146789504 hasConcept C2780493683 @default.
- W2146789504 hasConcept C43791021 @default.
- W2146789504 hasConcept C542102704 @default.
- W2146789504 hasConcept C548259974 @default.
- W2146789504 hasConcept C71924100 @default.
- W2146789504 hasConceptScore W2146789504C134018914 @default.
- W2146789504 hasConceptScore W2146789504C15744967 @default.
- W2146789504 hasConceptScore W2146789504C169760540 @default.
- W2146789504 hasConceptScore W2146789504C2778117688 @default.
- W2146789504 hasConceptScore W2146789504C2778882171 @default.
- W2146789504 hasConceptScore W2146789504C2779918689 @default.
- W2146789504 hasConceptScore W2146789504C2780493683 @default.
- W2146789504 hasConceptScore W2146789504C43791021 @default.
- W2146789504 hasConceptScore W2146789504C542102704 @default.
- W2146789504 hasConceptScore W2146789504C548259974 @default.
- W2146789504 hasConceptScore W2146789504C71924100 @default.
- W2146789504 hasIssue "5" @default.
- W2146789504 hasLocation W21467895041 @default.
- W2146789504 hasLocation W21467895042 @default.
- W2146789504 hasLocation W21467895043 @default.
- W2146789504 hasOpenAccess W2146789504 @default.
- W2146789504 hasPrimaryLocation W21467895041 @default.
- W2146789504 hasRelatedWork W1781684163 @default.
- W2146789504 hasRelatedWork W191642352 @default.
- W2146789504 hasRelatedWork W1969607064 @default.
- W2146789504 hasRelatedWork W1973759940 @default.
- W2146789504 hasRelatedWork W1998661104 @default.
- W2146789504 hasRelatedWork W2004368583 @default.
- W2146789504 hasRelatedWork W2043249689 @default.
- W2146789504 hasRelatedWork W2058730398 @default.
- W2146789504 hasRelatedWork W3143397474 @default.
- W2146789504 hasRelatedWork W70338752 @default.
- W2146789504 hasVolume "130" @default.
- W2146789504 isParatext "false" @default.
- W2146789504 isRetracted "false" @default.
- W2146789504 magId "2146789504" @default.
- W2146789504 workType "article" @default.