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• W2146789552 abstract "[reaction: see text]. The copper acetate mediated intramolecular O-arylation of phenols with phenylboronic acid pseudopeptides is the key step in the preparation of macrocyclic biphenyl ether hydroxamic acid inhibitors of collagenase 1 and gelatinases A and B. The intramolecular macrocyclization was found to be mild and tolerant of common chemical functionality. This methodology should provide a general route to macrocyclic biphenyl ethers." @default.
• W2146789552 created "2016-06-24" @default.
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• W2146789552 date "2001-03-09" @default.
• W2146789552 modified "2023-10-17" @default.
• W2146789552 title "Intramolecular O-Arylation of Phenols with Phenylboronic Acids: Application to the Synthesis of Macrocyclic Metalloproteinase Inhibitors" @default.
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• W2146789552 doi "https://doi.org/10.1021/ol015572i" @default.
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