Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146801185> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2146801185 abstract "The rate of hydrolytic degradation of N-methyl-2,4-dithiophenobarbital by spectrophotometric and separation methods was studied. The rate constants, order of reaction, activation energy, and pKa values were calculated based on the measurements of absorbance in the UV range. The changes in the absorbance values over time for solutions of different pH were analysed. Based on the obtained results, it was found that the hydrolysis of N-methyl-2,4-dithiophenobarbital followed the kinetics of a pseudo-first order reaction. Plots illustrating dependences, log k, and pH indicate the catalytic effect of OH– ions on the occurring process. The results show that in an alkaline environment the pyrimidine ring undergoes cleavage in the 1–6 position, and gradual desulfurization. The obtained results were compared with data for phenobarbital, 2-thiophenobarbital, and 2,4-dithiophenobarbital. It can be concluded that the change of an oxygen atom to a sulfur atom in the ring of a barbituric acid derivative causes an easier decomposition of the compound. However, the insertion of a methyl group on the nitrogen atom increases the durability of the compound." @default.
- W2146801185 created "2016-06-24" @default.
- W2146801185 creator A5016032034 @default.
- W2146801185 creator A5037225061 @default.
- W2146801185 creator A5052285896 @default.
- W2146801185 creator A5054286223 @default.
- W2146801185 creator A5060392081 @default.
- W2146801185 date "2016-01-01" @default.
- W2146801185 modified "2023-09-26" @default.
- W2146801185 title "Kinetics of Hydrolysis of N-Methyl-2,4-dithiophenobarbital" @default.
- W2146801185 cites W1003982499 @default.
- W2146801185 cites W11444415 @default.
- W2146801185 cites W1529530883 @default.
- W2146801185 cites W1971033524 @default.
- W2146801185 cites W1988665709 @default.
- W2146801185 cites W1991134705 @default.
- W2146801185 cites W1995115753 @default.
- W2146801185 cites W2023854159 @default.
- W2146801185 cites W2024607790 @default.
- W2146801185 cites W2031518807 @default.
- W2146801185 cites W2032240090 @default.
- W2146801185 cites W2034739698 @default.
- W2146801185 cites W2048190256 @default.
- W2146801185 cites W2052847327 @default.
- W2146801185 cites W206040971 @default.
- W2146801185 cites W2063642486 @default.
- W2146801185 cites W2063771833 @default.
- W2146801185 cites W2070810029 @default.
- W2146801185 cites W2079506489 @default.
- W2146801185 cites W2084800805 @default.
- W2146801185 cites W2085396840 @default.
- W2146801185 cites W2087101357 @default.
- W2146801185 cites W2114440733 @default.
- W2146801185 cites W2121078258 @default.
- W2146801185 cites W2159105215 @default.
- W2146801185 cites W2165316182 @default.
- W2146801185 cites W2168932255 @default.
- W2146801185 cites W2328154366 @default.
- W2146801185 cites W2410469455 @default.
- W2146801185 cites W2415512575 @default.
- W2146801185 cites W2439041465 @default.
- W2146801185 doi "https://doi.org/10.1071/ch15184" @default.
- W2146801185 hasPublicationYear "2016" @default.
- W2146801185 type Work @default.
- W2146801185 sameAs 2146801185 @default.
- W2146801185 citedByCount "0" @default.
- W2146801185 crossrefType "journal-article" @default.
- W2146801185 hasAuthorship W2146801185A5016032034 @default.
- W2146801185 hasAuthorship W2146801185A5037225061 @default.
- W2146801185 hasAuthorship W2146801185A5052285896 @default.
- W2146801185 hasAuthorship W2146801185A5054286223 @default.
- W2146801185 hasAuthorship W2146801185A5060392081 @default.
- W2146801185 hasConcept C121332964 @default.
- W2146801185 hasConcept C124681953 @default.
- W2146801185 hasConcept C147789679 @default.
- W2146801185 hasConcept C148898269 @default.
- W2146801185 hasConcept C155647269 @default.
- W2146801185 hasConcept C161790260 @default.
- W2146801185 hasConcept C178790620 @default.
- W2146801185 hasConcept C179104552 @default.
- W2146801185 hasConcept C185592680 @default.
- W2146801185 hasConcept C191503008 @default.
- W2146801185 hasConcept C2779793070 @default.
- W2146801185 hasConcept C43617362 @default.
- W2146801185 hasConcept C518881349 @default.
- W2146801185 hasConcept C62520636 @default.
- W2146801185 hasConcept C65024703 @default.
- W2146801185 hasConcept C93391505 @default.
- W2146801185 hasConcept C94412978 @default.
- W2146801185 hasConcept C95121573 @default.
- W2146801185 hasConcept C98015330 @default.
- W2146801185 hasConceptScore W2146801185C121332964 @default.
- W2146801185 hasConceptScore W2146801185C124681953 @default.
- W2146801185 hasConceptScore W2146801185C147789679 @default.
- W2146801185 hasConceptScore W2146801185C148898269 @default.
- W2146801185 hasConceptScore W2146801185C155647269 @default.
- W2146801185 hasConceptScore W2146801185C161790260 @default.
- W2146801185 hasConceptScore W2146801185C178790620 @default.
- W2146801185 hasConceptScore W2146801185C179104552 @default.
- W2146801185 hasConceptScore W2146801185C185592680 @default.
- W2146801185 hasConceptScore W2146801185C191503008 @default.
- W2146801185 hasConceptScore W2146801185C2779793070 @default.
- W2146801185 hasConceptScore W2146801185C43617362 @default.
- W2146801185 hasConceptScore W2146801185C518881349 @default.
- W2146801185 hasConceptScore W2146801185C62520636 @default.
- W2146801185 hasConceptScore W2146801185C65024703 @default.
- W2146801185 hasConceptScore W2146801185C93391505 @default.
- W2146801185 hasConceptScore W2146801185C94412978 @default.
- W2146801185 hasConceptScore W2146801185C95121573 @default.
- W2146801185 hasConceptScore W2146801185C98015330 @default.
- W2146801185 hasLocation W21468011851 @default.
- W2146801185 hasOpenAccess W2146801185 @default.
- W2146801185 hasPrimaryLocation W21468011851 @default.
- W2146801185 isParatext "false" @default.
- W2146801185 isRetracted "false" @default.
- W2146801185 magId "2146801185" @default.
- W2146801185 workType "article" @default.