Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146827571> ?p ?o ?g. }
- W2146827571 endingPage "e0139506" @default.
- W2146827571 startingPage "e0139506" @default.
- W2146827571 abstract "To determine the function of Annexin A2 (Axna2) in mouse embryo implantation in vivo, experimental manipulation of Axna2 activities was performed in mouse endometrial tissue in vivo and in vitro. Histological examination of endometrial tissues was performed throughout the reproduction cycle and after steroid treatment. Embryo implantation was determined after blockage of the Axna2 activities by siRNA or anti-Axna2 antibody. The expression of Axna2 immunoreactivies in the endometrial luminal epithelium changed cyclically in the estrus cycle and was upregulated by estrogen. After nidatory estrogen surge, there was a concentration of Axna2 immunoreactivities at the interface between the implanting embryo and the luminal epithelium. The phenomenon was likely to be induced by the implanting embryos as no such concentration of signal was observed in the inter-implantation sites and in pseudopregnancy. Knockdown of Axna2 by siRNA reduced attachment of mouse blastocysts onto endometrial tissues in vitro. Consistently, the number of implantation sites was significantly reduced after infusion of anti-Axna2 antibody into the uterine cavity. Steroids and embryos modulate the expression of Axna2 in the endometrial epithelium. Axna2 may function as an adhesion molecule during embryo implantation in mice." @default.
- W2146827571 created "2016-06-24" @default.
- W2146827571 creator A5004229878 @default.
- W2146827571 creator A5040040696 @default.
- W2146827571 creator A5044294629 @default.
- W2146827571 creator A5067880078 @default.
- W2146827571 creator A5069024030 @default.
- W2146827571 creator A5077664084 @default.
- W2146827571 creator A5086991220 @default.
- W2146827571 date "2015-10-07" @default.
- W2146827571 modified "2023-09-30" @default.
- W2146827571 title "Annexin A2 Acts as an Adhesion Molecule on the Endometrial Epithelium during Implantation in Mice" @default.
- W2146827571 cites W1486248748 @default.
- W2146827571 cites W1542304810 @default.
- W2146827571 cites W1963709597 @default.
- W2146827571 cites W1968534662 @default.
- W2146827571 cites W1968742573 @default.
- W2146827571 cites W1972521538 @default.
- W2146827571 cites W1975848874 @default.
- W2146827571 cites W1977956805 @default.
- W2146827571 cites W1986770691 @default.
- W2146827571 cites W1990030459 @default.
- W2146827571 cites W1998242092 @default.
- W2146827571 cites W1999477520 @default.
- W2146827571 cites W2006426538 @default.
- W2146827571 cites W2006878196 @default.
- W2146827571 cites W2023940500 @default.
- W2146827571 cites W2024929637 @default.
- W2146827571 cites W2035810647 @default.
- W2146827571 cites W2073635099 @default.
- W2146827571 cites W2080174494 @default.
- W2146827571 cites W2083757415 @default.
- W2146827571 cites W2085052924 @default.
- W2146827571 cites W2086947113 @default.
- W2146827571 cites W2109248466 @default.
- W2146827571 cites W2113768757 @default.
- W2146827571 cites W2114360996 @default.
- W2146827571 cites W2123080882 @default.
- W2146827571 cites W2127150853 @default.
- W2146827571 cites W2132117256 @default.
- W2146827571 cites W2150737928 @default.
- W2146827571 cites W2151774983 @default.
- W2146827571 cites W2154872869 @default.
- W2146827571 cites W2155653188 @default.
- W2146827571 cites W2160022616 @default.
- W2146827571 doi "https://doi.org/10.1371/journal.pone.0139506" @default.
- W2146827571 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4596619" @default.
- W2146827571 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26444699" @default.
- W2146827571 hasPublicationYear "2015" @default.
- W2146827571 type Work @default.
- W2146827571 sameAs 2146827571 @default.
- W2146827571 citedByCount "18" @default.
- W2146827571 countsByYear W21468275712017 @default.
- W2146827571 countsByYear W21468275712018 @default.
- W2146827571 countsByYear W21468275712019 @default.
- W2146827571 countsByYear W21468275712020 @default.
- W2146827571 countsByYear W21468275712021 @default.
- W2146827571 countsByYear W21468275712022 @default.
- W2146827571 countsByYear W21468275712023 @default.
- W2146827571 crossrefType "journal-article" @default.
- W2146827571 hasAuthorship W2146827571A5004229878 @default.
- W2146827571 hasAuthorship W2146827571A5040040696 @default.
- W2146827571 hasAuthorship W2146827571A5044294629 @default.
- W2146827571 hasAuthorship W2146827571A5067880078 @default.
- W2146827571 hasAuthorship W2146827571A5069024030 @default.
- W2146827571 hasAuthorship W2146827571A5077664084 @default.
- W2146827571 hasAuthorship W2146827571A5086991220 @default.
- W2146827571 hasBestOaLocation W21468275711 @default.
- W2146827571 hasConcept C126322002 @default.
- W2146827571 hasConcept C134018914 @default.
- W2146827571 hasConcept C150903083 @default.
- W2146827571 hasConcept C16685009 @default.
- W2146827571 hasConcept C185592680 @default.
- W2146827571 hasConcept C196843134 @default.
- W2146827571 hasConcept C1998276 @default.
- W2146827571 hasConcept C202751555 @default.
- W2146827571 hasConcept C207001950 @default.
- W2146827571 hasConcept C2777164284 @default.
- W2146827571 hasConcept C2779742232 @default.
- W2146827571 hasConcept C529295009 @default.
- W2146827571 hasConcept C54355233 @default.
- W2146827571 hasConcept C55493867 @default.
- W2146827571 hasConcept C71924100 @default.
- W2146827571 hasConcept C86803240 @default.
- W2146827571 hasConcept C88634738 @default.
- W2146827571 hasConcept C95444343 @default.
- W2146827571 hasConceptScore W2146827571C126322002 @default.
- W2146827571 hasConceptScore W2146827571C134018914 @default.
- W2146827571 hasConceptScore W2146827571C150903083 @default.
- W2146827571 hasConceptScore W2146827571C16685009 @default.
- W2146827571 hasConceptScore W2146827571C185592680 @default.
- W2146827571 hasConceptScore W2146827571C196843134 @default.
- W2146827571 hasConceptScore W2146827571C1998276 @default.
- W2146827571 hasConceptScore W2146827571C202751555 @default.
- W2146827571 hasConceptScore W2146827571C207001950 @default.
- W2146827571 hasConceptScore W2146827571C2777164284 @default.
- W2146827571 hasConceptScore W2146827571C2779742232 @default.
- W2146827571 hasConceptScore W2146827571C529295009 @default.