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• W2146852783 startingPage "349" @default.
• W2146852783 abstract "Based on the premise that dietary nitrate is detrimental to human health, increasingly stringent regulations are being instituted to lower nitrate levels in food and water. Not only does this pose a financial challenge to water boards and a threat to vegetable production in Northern Europe, but also may be eliminating an important non-immune mechanism for host defence. Until recently nitrate was perceived as a purely harmful dietary component which causes infantile methaemoglobinaemia, carcinogenesis and possibly even teratogenesis. Epidemiological studies have failed to substantiate this. It has been shown that dietary nitrate undergoes enterosalivary circulation. It is recirculated in the blood, concentrated by the salivary glands, secreted in the saliva and reduced to nitrite by facultative Gram-positive anaerobes ( Staphylococcus sciuri and S. intermedius ) on the tongue. Salivary nitrite is swallowed into the acidic stomach where it is reduced to large quantities of NO and other oxides of N and, conceivably, also contributes to the formation of systemic S-nitrosothiols. NO and solutions of acidified nitrite, mimicking gastric conditions, have been shown to have antimicrobial activity against a wide range of organisms. In particular, acidified nitrite is bactericidal for a variety of gastrointestinal pathogens such as Yersinia and Salmonella. NO is known to have vasodilator properties and to modulate platelet function, as are S-nitrosothiols. Thus, nitrate in the diet, which determines reactive nitrogen oxide species production in the stomach (McKnight et al. 1997), is emerging as an effective host defence against gastrointestinal pathogens, as a modulator of platelet activity and possibly even of gastrointestinal motility and microcirculation. Therefore dietary nitrate may have an important therapeutic role to play, not least in the immunocompromised and in refugees who are at particular risk of contracting gastroenteritides." @default.
• W2146852783 created "2016-06-24" @default.
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• W2146852783 date "1999-05-01" @default.
• W2146852783 modified "2023-10-16" @default.
• W2146852783 title "Dietary nitrate in man: friend or foe?" @default.
• W2146852783 cites W1497814715 @default.
• W2146852783 cites W1594550515 @default.
• W2146852783 cites W1611496487 @default.
• W2146852783 cites W177413424 @default.
• W2146852783 cites W1812961065 @default.
• W2146852783 cites W1883934427 @default.
• W2146852783 cites W1923609106 @default.
• W2146852783 cites W1960794181 @default.
• W2146852783 cites W1964996063 @default.
• W2146852783 cites W1972485524 @default.
• W2146852783 cites W1975549825 @default.
• W2146852783 cites W1979230311 @default.
• W2146852783 cites W1979861674 @default.
• W2146852783 cites W1990661275 @default.
• W2146852783 cites W1997404527 @default.
• W2146852783 cites W1997559287 @default.
• W2146852783 cites W2002338268 @default.
• W2146852783 cites W2003346387 @default.
• W2146852783 cites W2003453668 @default.
• W2146852783 cites W2003479475 @default.
• W2146852783 cites W2004577640 @default.
• W2146852783 cites W2005515164 @default.
• W2146852783 cites W2013766389 @default.
• W2146852783 cites W2013978689 @default.
• W2146852783 cites W2016153142 @default.
• W2146852783 cites W2019384037 @default.
• W2146852783 cites W2019946018 @default.
• W2146852783 cites W2027548474 @default.
• W2146852783 cites W2036352285 @default.
• W2146852783 cites W2036461366 @default.
• W2146852783 cites W2039949381 @default.
• W2146852783 cites W2040852689 @default.
• W2146852783 cites W2040989517 @default.
• W2146852783 cites W2043562592 @default.
• W2146852783 cites W2043722890 @default.
• W2146852783 cites W2050902441 @default.
• W2146852783 cites W2052449687 @default.
• W2146852783 cites W2059241041 @default.
• W2146852783 cites W2059456575 @default.
• W2146852783 cites W2064514516 @default.
• W2146852783 cites W2066088611 @default.
• W2146852783 cites W2067251507 @default.
• W2146852783 cites W2067454694 @default.
• W2146852783 cites W2070922892 @default.
• W2146852783 cites W2071351642 @default.
• W2146852783 cites W2071755029 @default.
• W2146852783 cites W2072646685 @default.
• W2146852783 cites W2077395072 @default.
• W2146852783 cites W2078259385 @default.
• W2146852783 cites W2081646807 @default.
• W2146852783 cites W2088388072 @default.
• W2146852783 cites W2088892406 @default.
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• W2146852783 cites W2096527916 @default.
• W2146852783 cites W2101975571 @default.
• W2146852783 cites W2102723961 @default.
• W2146852783 cites W2104747639 @default.
• W2146852783 cites W2108012416 @default.
• W2146852783 cites W2120620942 @default.
• W2146852783 cites W2125585698 @default.
• W2146852783 cites W2129294258 @default.
• W2146852783 cites W2131085070 @default.
• W2146852783 cites W2144413971 @default.
• W2146852783 cites W2145542684 @default.
• W2146852783 cites W2155174937 @default.
• W2146852783 cites W2155734059 @default.
• W2146852783 cites W2165338993 @default.
• W2146852783 cites W2169182236 @default.
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• W2146852783 cites W2233447257 @default.
• W2146852783 cites W2233950908 @default.
• W2146852783 cites W2313094381 @default.
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• W2146852783 doi "https://doi.org/10.1017/s000711459900063x" @default.
• W2146852783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10615207" @default.
• W2146852783 hasPublicationYear "1999" @default.
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