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• W2146875307 abstract "Several brominated tyrosine derived compounds, psammaplins A (1), K (2) and L (3) as well as bisaprasin (4) were isolated from the Fijian marine sponge Aplysinella rhax during a bioassay guided isolation protocol. Their structures were determined using NMR and MS techniques. Psammaplin A was found to moderately inhibit chitinase B from Serratia marcescens, the mode of inhibition being non-competitive. Crystallographic studies suggest that a disordered psammaplin A molecule is bound near the active site. Interestingly, psammaplin A was found to be a potent antifungal agent." @default.
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• W2146875307 date "2002-04-01" @default.
• W2146875307 modified "2023-10-15" @default.
• W2146875307 title "Psammaplin A, a chitinase inhibitor isolated from the fijian marine sponge Aplysinella rhax" @default.
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• W2146875307 doi "https://doi.org/10.1016/s0968-0896(01)00372-8" @default.
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