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- W2146885452 abstract "To evaluate the usefulness of routine monitoring of serum lamotrigine concentration.Literature was accessed through MEDLINE (1990-January 2001). Key search terms included lamotrigine, pharmacokinetics, and epilepsy.A decision-making algorithm was used to evaluate the clinical evidence to support or refute the routine use of serum lamotrigine concentrations to adjust doses. The value of serum lamotrigine concentration monitoring remains controversial, primarily because clear relationships between concentration and pharmacologic response (either efficacy or toxicity) have not been demonstrated.Serum concentration monitoring of lamotrigine is not recommended as a tool for routine dose adjustment." @default.
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- W2146885452 date "2002-05-01" @default.
- W2146885452 modified "2023-09-26" @default.
- W2146885452 title "Therapeutic Drug Monitoring of Lamotrigine" @default.
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- W2146885452 doi "https://doi.org/10.1345/aph.1a252" @default.
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