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- W2146900903 abstract "Antibiotic-associated diarrhea is common in both inpatient and outpatient settings, and 15% to 20% of the cases are caused by Clostridium difficile. 1 Al though antibiotic therapy with metronidazole or other agents is effective for most patients with C difficile-associated diarrhea, approximately 10% to 20% of patients receiving treatment for C difficile infection will experience a relapse following dis continuation of initial therapy,2 and relapses are often multiple. This clinical problem can be fre quent and frustrating. C difficile-associated diarrhea is thought to occur when an alteration of the normal bacterial flora of the intestinal tract permits proliferation of toxi genic strains of C difficile. Various microorganisms have been used therapeutically to repopulate the intestinal flora to enhance resistance against C dif ficile. A randomized placebo-controlled trial has shown that the yeast Saccharomyces boulardii is ef fective for the treatment of recurrent C difficile disease. 3 This biotherapeutic agent, however, is not available as a pharmaceutical preparation in the United States. We report herein a case of C difficile associated diarrhea with multiple relapses that re sponded to treatment with antibiotics together with a commercial baker's yeast (Fleischmann's Yeast), which contains the closely related species Saccharo myces cerevisiae at a concentration of organisms at 1 o to/g." @default.
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- W2146900903 date "2000-03-01" @default.
- W2146900903 modified "2023-09-25" @default.
- W2146900903 title "Recurrent Clostridium difficile-Associated Diarrhea and Colitis Treated with Saccharomyces cerevisiae (Baker's Yeast) in Combination with Antibiotic Therapy: A Case Report" @default.
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- W2146900903 doi "https://doi.org/10.3122/15572625-13-2-138" @default.
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