FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146910769> ?p ?o ?g. }

• W2146910769 endingPage "916" @default.
• W2146910769 startingPage "909" @default.
• W2146910769 abstract "Mycobacterium tuberculosis strains CDC1551 and Erdman were used to assess cytotoxicity in infected A549 human alveolar epithelial cell monolayers. Strain CDC1551 was found to induce qualitatively greater disruption of A549 monolayers than was strain Erdman, although total intracellular and cell-associated bacterial growth rates over the course of the infections were not significantly different. Cell-free culture supernatants from human monocytic cells infected with either of the 2 M. tuberculosis strains produced a cytotoxic effect on A549 cells, correlating with the amount of tumor necrosis factor alpha (TNF-α) released by the infected monocytes. The addition of TNF-α-neutralizing antibodies to the supernatants from infected monocyte cultures did prevent the induction of a cytotoxic effect on A549 cells overlaid with this mixture but did not prevent the death of epithelial cells when added prior to infection with M. tuberculosis bacilli. Thus, these data agree with previous observations that lung epithelial cells infected with M. tuberculosis bacilli are rapidly killed in vitro. In addition, the data indicate that some of the observed epithelial cell killing may be collateral damage; the result of TNF-α released from M. tuberculosis-infected monocytes." @default.
• W2146910769 created "2016-06-24" @default.
• W2146910769 creator A5009089009 @default.
• W2146910769 creator A5026874509 @default.
• W2146910769 creator A5040550293 @default.
• W2146910769 creator A5061729227 @default.
• W2146910769 date "2012-07-01" @default.
• W2146910769 modified "2023-10-14" @default.
• W2146910769 title "Dual mechanism for<i>Mycobacterium tuberculosis</i>cytotoxicity on lung epithelial cells" @default.
• W2146910769 cites W1485006334 @default.
• W2146910769 cites W1545137912 @default.
• W2146910769 cites W1618386398 @default.
• W2146910769 cites W1638738262 @default.
• W2146910769 cites W1968925362 @default.
• W2146910769 cites W1972703563 @default.
• W2146910769 cites W1977633925 @default.
• W2146910769 cites W2000921800 @default.
• W2146910769 cites W2002519936 @default.
• W2146910769 cites W2012832990 @default.
• W2146910769 cites W2032537032 @default.
• W2146910769 cites W2039304319 @default.
• W2146910769 cites W2050896753 @default.
• W2146910769 cites W2064173499 @default.
• W2146910769 cites W2079798802 @default.
• W2146910769 cites W2094942027 @default.
• W2146910769 cites W2103985124 @default.
• W2146910769 cites W2104415540 @default.
• W2146910769 cites W2108210947 @default.
• W2146910769 cites W2114004413 @default.
• W2146910769 cites W2118808041 @default.
• W2146910769 cites W2120332982 @default.
• W2146910769 cites W2124001620 @default.
• W2146910769 cites W2131604051 @default.
• W2146910769 cites W2141912213 @default.
• W2146910769 cites W2143303543 @default.
• W2146910769 cites W2149460956 @default.
• W2146910769 cites W2150322683 @default.
• W2146910769 cites W2151738661 @default.
• W2146910769 cites W2163188970 @default.
• W2146910769 cites W2165094248 @default.
• W2146910769 cites W2172675059 @default.
• W2146910769 doi "https://doi.org/10.1139/w2012-067" @default.
• W2146910769 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22720783" @default.
• W2146910769 hasPublicationYear "2012" @default.
• W2146910769 type Work @default.
• W2146910769 sameAs 2146910769 @default.
• W2146910769 citedByCount "11" @default.
• W2146910769 countsByYear W21469107692015 @default.
• W2146910769 countsByYear W21469107692017 @default.
• W2146910769 countsByYear W21469107692019 @default.
• W2146910769 countsByYear W21469107692020 @default.
• W2146910769 countsByYear W21469107692021 @default.
• W2146910769 countsByYear W21469107692023 @default.
• W2146910769 crossrefType "journal-article" @default.
• W2146910769 hasAuthorship W2146910769A5009089009 @default.
• W2146910769 hasAuthorship W2146910769A5026874509 @default.
• W2146910769 hasAuthorship W2146910769A5040550293 @default.
• W2146910769 hasAuthorship W2146910769A5061729227 @default.
• W2146910769 hasConcept C109316439 @default.
• W2146910769 hasConcept C142724271 @default.
• W2146910769 hasConcept C1491633281 @default.
• W2146910769 hasConcept C153911025 @default.
• W2146910769 hasConcept C154317977 @default.
• W2146910769 hasConcept C17991360 @default.
• W2146910769 hasConcept C202751555 @default.
• W2146910769 hasConcept C203014093 @default.
• W2146910769 hasConcept C2777975735 @default.
• W2146910769 hasConcept C2781069245 @default.
• W2146910769 hasConcept C2781184567 @default.
• W2146910769 hasConcept C54355233 @default.
• W2146910769 hasConcept C55493867 @default.
• W2146910769 hasConcept C71924100 @default.
• W2146910769 hasConcept C79879829 @default.
• W2146910769 hasConcept C81729549 @default.
• W2146910769 hasConcept C81885089 @default.
• W2146910769 hasConcept C86803240 @default.
• W2146910769 hasConcept C89423630 @default.
• W2146910769 hasConcept C95444343 @default.
• W2146910769 hasConceptScore W2146910769C109316439 @default.
• W2146910769 hasConceptScore W2146910769C142724271 @default.
• W2146910769 hasConceptScore W2146910769C1491633281 @default.
• W2146910769 hasConceptScore W2146910769C153911025 @default.
• W2146910769 hasConceptScore W2146910769C154317977 @default.
• W2146910769 hasConceptScore W2146910769C17991360 @default.
• W2146910769 hasConceptScore W2146910769C202751555 @default.
• W2146910769 hasConceptScore W2146910769C203014093 @default.
• W2146910769 hasConceptScore W2146910769C2777975735 @default.
• W2146910769 hasConceptScore W2146910769C2781069245 @default.
• W2146910769 hasConceptScore W2146910769C2781184567 @default.
• W2146910769 hasConceptScore W2146910769C54355233 @default.
• W2146910769 hasConceptScore W2146910769C55493867 @default.
• W2146910769 hasConceptScore W2146910769C71924100 @default.
• W2146910769 hasConceptScore W2146910769C79879829 @default.
• W2146910769 hasConceptScore W2146910769C81729549 @default.
• W2146910769 hasConceptScore W2146910769C81885089 @default.
• W2146910769 hasConceptScore W2146910769C86803240 @default.
• W2146910769 hasConceptScore W2146910769C89423630 @default.
• W2146910769 hasConceptScore W2146910769C95444343 @default.

• next