FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2146980410> ?p ?o ?g. }

• W2146980410 endingPage "2297" @default.
• W2146980410 startingPage "2289" @default.
• W2146980410 abstract "Does maternal exposure during pregnancy to higher ambient temperature increase the risk of congenital heart defects (CHDs)? Significant associations were found between maternal exposure during pregnancy to higher ambient temperature and CHDs risk especially during the cold season. From rodents to non-human primates, a teratogenic effect of hyperthermic insult has been demonstrated. There are fewer data regarding the effect on the human fetus and specifically the association between maternal exposures during pregnancy to higher ambient temperature and CHDs. This population registry-based cohort study included 135 527 live and stillbirths in the Tel-Aviv region of Israel in 2000–2006. Two clinical diagnostic groups of isolated cardiac defects (atrial septal defects and ventricular septal defects: n = 542 and 481, respectively) and one group of multiple cardiac defects (defined by the presence of two or more cardiac malformations, n = 607) were studied. Temperature measurements were constructed from ambient stations and used to assess the impact of maternal exposure to average ambient temperature and extreme heat events (daily average temperature above the 90th percentile) during Weeks 3–8 of pregnancy on risk of CHDs. Logistic models, adjusted for sociodemographic covariates, were used to evaluate the associations between temperature and CHDs. Overall, we found no significant associations between ambient temperature and CHDs throughout the year, with one exception for multiple CHDs. After stratifying by season of conception, continuous exposure to average ambient temperature and maximum peak temperature (1°C increase) during the cold season increased the risk for multiple CHDs [odds ratio (OR) 1.05, 95% confidence interval (CI): 1.00, 1.10 and OR 1.03, 95% CI: 1.01, 1.05, respectively]. A 1-day increase in extreme heat events increased the risk for multiple CHDs (OR 1.13, 95% CI: 1.06, 1.21) and also for isolated atrial septal defects (OR 1.10, 95% CI: 1.02, 1.19). Information both on CHD cases and on ambient temperature was based on registries and it is possible that this may cause some misclassification. In urban areas, pregnant women may be exposed to higher temperatures than recorded by ambient monitors because of the ‘heat island effect’. Furthermore, data for the amount of time spent indoors were unavailable and this could have resulted in exposure misclassification. The findings are important within the context of global climate change, which may have implications for public health in countries with mild winters and hot summers. This study was supported by the Israeli Ministry of Environmental Protection (research grant-7-2-7) and by the Environment and Health Fund (PhD Fellowship Program). There are no competing interests." @default.
• W2146980410 created "2016-06-24" @default.
• W2146980410 creator A5005266138 @default.
• W2146980410 creator A5007374643 @default.
• W2146980410 creator A5061930102 @default.
• W2146980410 creator A5063284741 @default.
• W2146980410 creator A5075657108 @default.
• W2146980410 creator A5087404491 @default.
• W2146980410 date "2013-06-05" @default.
• W2146980410 modified "2023-09-23" @default.
• W2146980410 title "Ambient temperature and congenital heart defects" @default.
• W2146980410 cites W1655742825 @default.
• W2146980410 cites W1963517200 @default.
• W2146980410 cites W1967762504 @default.
• W2146980410 cites W1971624740 @default.
• W2146980410 cites W1980327088 @default.
• W2146980410 cites W1980378023 @default.
• W2146980410 cites W1999457225 @default.
• W2146980410 cites W2012644846 @default.
• W2146980410 cites W2025537603 @default.
• W2146980410 cites W2031708466 @default.
• W2146980410 cites W2033062816 @default.
• W2146980410 cites W2049709876 @default.
• W2146980410 cites W2056694298 @default.
• W2146980410 cites W2057226779 @default.
• W2146980410 cites W2083957906 @default.
• W2146980410 cites W2096713885 @default.
• W2146980410 cites W2099982550 @default.
• W2146980410 cites W2100798142 @default.
• W2146980410 cites W2104610368 @default.
• W2146980410 cites W2117952499 @default.
• W2146980410 cites W2120114793 @default.
• W2146980410 cites W2125307813 @default.
• W2146980410 cites W2150733612 @default.
• W2146980410 cites W2155336237 @default.
• W2146980410 cites W2164071690 @default.
• W2146980410 cites W2165674903 @default.
• W2146980410 cites W4232383013 @default.
• W2146980410 cites W4241526697 @default.
• W2146980410 cites W44429629 @default.
• W2146980410 doi "https://doi.org/10.1093/humrep/det244" @default.
• W2146980410 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23739216" @default.
• W2146980410 hasPublicationYear "2013" @default.
• W2146980410 type Work @default.
• W2146980410 sameAs 2146980410 @default.
• W2146980410 citedByCount "39" @default.
• W2146980410 countsByYear W21469804102014 @default.
• W2146980410 countsByYear W21469804102015 @default.
• W2146980410 countsByYear W21469804102016 @default.
• W2146980410 countsByYear W21469804102017 @default.
• W2146980410 countsByYear W21469804102018 @default.
• W2146980410 countsByYear W21469804102019 @default.
• W2146980410 countsByYear W21469804102021 @default.
• W2146980410 countsByYear W21469804102022 @default.
• W2146980410 countsByYear W21469804102023 @default.
• W2146980410 crossrefType "journal-article" @default.
• W2146980410 hasAuthorship W2146980410A5005266138 @default.
• W2146980410 hasAuthorship W2146980410A5007374643 @default.
• W2146980410 hasAuthorship W2146980410A5061930102 @default.
• W2146980410 hasAuthorship W2146980410A5063284741 @default.
• W2146980410 hasAuthorship W2146980410A5075657108 @default.
• W2146980410 hasAuthorship W2146980410A5087404491 @default.
• W2146980410 hasConcept C105795698 @default.
• W2146980410 hasConcept C122048520 @default.
• W2146980410 hasConcept C126322002 @default.
• W2146980410 hasConcept C131872663 @default.
• W2146980410 hasConcept C156957248 @default.
• W2146980410 hasConcept C187212893 @default.
• W2146980410 hasConcept C2779234561 @default.
• W2146980410 hasConcept C2908647359 @default.
• W2146980410 hasConcept C33923547 @default.
• W2146980410 hasConcept C44249647 @default.
• W2146980410 hasConcept C54355233 @default.
• W2146980410 hasConcept C71924100 @default.
• W2146980410 hasConcept C86803240 @default.
• W2146980410 hasConcept C99454951 @default.
• W2146980410 hasConceptScore W2146980410C105795698 @default.
• W2146980410 hasConceptScore W2146980410C122048520 @default.
• W2146980410 hasConceptScore W2146980410C126322002 @default.
• W2146980410 hasConceptScore W2146980410C131872663 @default.
• W2146980410 hasConceptScore W2146980410C156957248 @default.
• W2146980410 hasConceptScore W2146980410C187212893 @default.
• W2146980410 hasConceptScore W2146980410C2779234561 @default.
• W2146980410 hasConceptScore W2146980410C2908647359 @default.
• W2146980410 hasConceptScore W2146980410C33923547 @default.
• W2146980410 hasConceptScore W2146980410C44249647 @default.
• W2146980410 hasConceptScore W2146980410C54355233 @default.
• W2146980410 hasConceptScore W2146980410C71924100 @default.
• W2146980410 hasConceptScore W2146980410C86803240 @default.
• W2146980410 hasConceptScore W2146980410C99454951 @default.
• W2146980410 hasIssue "8" @default.
• W2146980410 hasLocation W21469804101 @default.
• W2146980410 hasLocation W21469804102 @default.
• W2146980410 hasOpenAccess W2146980410 @default.
• W2146980410 hasPrimaryLocation W21469804101 @default.
• W2146980410 hasRelatedWork W1976872798 @default.
• W2146980410 hasRelatedWork W2023040232 @default.
• W2146980410 hasRelatedWork W2088142818 @default.

• next