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- W2147056496 abstract "Abstract: As coronary artery bypass grafting (CABG) surgery in the beating heart technique is progressing, new devices have been developed to overcome hemodynamic instabilities while tilting the heart for exposure of back wall vessels. A new device for in heart biventricular intracorporeal circulation was applied in 42 patients undergoing CABG surgery (Group 1). The control group consisted of 38 patients operated on using a conventional cardiopulmonary bypass setup (Group 2). The study protocol of the prospective, randomized multicenter study was approved by the local ethics committees. Patients were included following inclusion criteria and patient informed consent. Mean age, procedure time, mean arterial pressure (MAP), and hemolysis by means of plasma free hemoglobin (fHb) were assessed preoperatively, perioperatively, on postoperative Days 1 to 3, at discharge, and at a 3 month follow‐up. The mean age was 62.1 (range 59–74) years (Group 1), 62.7 (range 48–72) years (Group 2); procedure time was 112 min ± 31.9 min (Group 1), 137.4 min ± 36.2 min (Group 2); and 2.3 ± 0.6 (Group 1), 2.2 ± 0.7 (Group 2), vessels were revascularized. The flow on pump was 3.7 (2.5/4.4) L/min (Group 1), 4.9 (3.6/6.2) L/min (Group 2) which resulted in a MAP of 69.8 (4.0/143) mm Hg (Group 1), 58.3 (5.3/94) mm Hg while assessing the vessels of the back wall. Hemolysis defined by fHB was lower than 20 mg/dl at all times pre‐ and postoperatively. Intraoperative maximum values were up to 100 mg/dl in 4 patients (2 in Group 1 and 2 in Group 2). Body mass index was 26.4 ± 2.6 (Group 1), 27.9 ± 3.2. New York Heart Association Class was II to III in both groups. There were no pump related life threatening or severe adverse events. Beating heart procedures with ICC can be reliably and safely achieved. As the device is easy to use, it may deserve a more widespread use in the future." @default.
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- W2147056496 date "2001-05-01" @default.
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- W2147056496 title "A New Intracardiac Microaxial Pump: First Results of a Multicenter Study" @default.
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- W2147056496 doi "https://doi.org/10.1046/j.1525-1594.2001.025005327.x" @default.
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