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- W2147112454 abstract "Diffuse large B-cell lymphoma (DLBCL) is the most common form of aggressive non-Hodgkin lymphoma, accounting for 30–40% of newly diagnosed cases. Obesity is a well-defined risk factor for DLBCL. However, the impact of body mass index (BMI) on DLBCL prognosis is controversial. Recent studies suggest that skeletal muscle wasting (sarcopenia) or loss of fat mass can be detected by computed tomography (CT) images and is useful for predicting the clinical outcome in several types of cancer including DLBCL. Several hypotheses have been proposed to explain the differences in DLBCL outcome according to BMI or weight that include tolerance to treatment, inflammatory background and chemotherapy or rituximab metabolism. In this review, we summarize the available literature, addressing the impact and physiopathological relevance of simple anthropometric tools including BMI and tissue distribution measurements. We also discuss their relationship with other nutritional parameters and their potential role in the management of patients with DLBCL." @default.
- W2147112454 created "2016-06-24" @default.
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- W2147112454 creator A5070329015 @default.
- W2147112454 creator A5082700087 @default.
- W2147112454 creator A5086354986 @default.
- W2147112454 date "2015-01-21" @default.
- W2147112454 modified "2023-10-14" @default.
- W2147112454 title "Body mass index and other anthropometric parameters in patients with diffuse large B-cell lymphoma: physiopathological significance and predictive value in the immunochemotherapy era" @default.
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- W2147112454 doi "https://doi.org/10.3109/10428194.2014.979412" @default.
- W2147112454 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25363401" @default.
- W2147112454 hasPublicationYear "2015" @default.
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