FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2147202382> ?p ?o ?g. }

• W2147202382 endingPage "8" @default.
• W2147202382 startingPage "604" @default.
• W2147202382 abstract "Numerous drugs such as clopidogrel have been developed to reduce coagulation or inhibit platelet function. The hepatic cytochrome P450 (CYP) pathway is involved in the conversion of clopidogrel to its active metabolite. A recent black-box warning was included in the clopidogrel package insert indicating a significant clinical link between specific CYP2C19 genetic variants and poor metabolism of clopidogrel. Of these variants, *2 and *3 are the most common and are associated with complete loss of enzyme activity. In patients who are carriers of a CYP2C19 *2 or *3 allele, the conversion of clopidogrel to its active metabolite may be reduced, which can lead to ischemic events and negative consequence for the patient. We examined the ability of the Verigene CLO assay (Nanosphere, Northbrook, IL) to identify CYP2C19 *2 and *3 polymorphisms in 1,286 unique whole blood samples. The Verigene CLO assay accurately identified homozygous and heterozygous *2 and *3 phenotypes with a specificity of 100% and a final call rate of 99.7%. The assay is fully automated and can produce a result in approximately 3.5 hours." @default.
• W2147202382 created "2016-06-24" @default.
• W2147202382 creator A5003913262 @default.
• W2147202382 creator A5012678918 @default.
• W2147202382 creator A5035619885 @default.
• W2147202382 creator A5041037541 @default.
• W2147202382 creator A5041081700 @default.
• W2147202382 creator A5051990712 @default.
• W2147202382 creator A5059333961 @default.
• W2147202382 creator A5067044899 @default.
• W2147202382 creator A5086933278 @default.
• W2147202382 date "2011-10-01" @default.
• W2147202382 modified "2023-09-25" @default.
• W2147202382 title "Evaluation of a microarray-based genotyping assay for the rapid detection of cytochrome P450 2C19 *2 and *3 polymorphisms from whole blood using nanoparticle probes." @default.
• W2147202382 cites W168371622 @default.
• W2147202382 cites W17607910 @default.
• W2147202382 cites W1972344741 @default.
• W2147202382 cites W1980374486 @default.
• W2147202382 cites W1989895642 @default.
• W2147202382 cites W2004877063 @default.
• W2147202382 cites W2015571727 @default.
• W2147202382 cites W2016202952 @default.
• W2147202382 cites W2023602049 @default.
• W2147202382 cites W2096085834 @default.
• W2147202382 cites W2114346603 @default.
• W2147202382 cites W2117393594 @default.
• W2147202382 cites W2124836611 @default.
• W2147202382 cites W2145425156 @default.
• W2147202382 cites W2154940301 @default.
• W2147202382 cites W2168580334 @default.
• W2147202382 cites W300595399 @default.
• W2147202382 doi "https://doi.org/10.1309/ajcpcpu9q2irnyxc" @default.
• W2147202382 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21917683" @default.
• W2147202382 hasPublicationYear "2011" @default.
• W2147202382 type Work @default.
• W2147202382 sameAs 2147202382 @default.
• W2147202382 citedByCount "20" @default.
• W2147202382 countsByYear W21472023822012 @default.
• W2147202382 countsByYear W21472023822013 @default.
• W2147202382 countsByYear W21472023822014 @default.
• W2147202382 countsByYear W21472023822015 @default.
• W2147202382 countsByYear W21472023822016 @default.
• W2147202382 countsByYear W21472023822018 @default.
• W2147202382 countsByYear W21472023822019 @default.
• W2147202382 crossrefType "journal-article" @default.
• W2147202382 hasAuthorship W2147202382A5003913262 @default.
• W2147202382 hasAuthorship W2147202382A5012678918 @default.
• W2147202382 hasAuthorship W2147202382A5035619885 @default.
• W2147202382 hasAuthorship W2147202382A5041037541 @default.
• W2147202382 hasAuthorship W2147202382A5041081700 @default.
• W2147202382 hasAuthorship W2147202382A5051990712 @default.
• W2147202382 hasAuthorship W2147202382A5059333961 @default.
• W2147202382 hasAuthorship W2147202382A5067044899 @default.
• W2147202382 hasAuthorship W2147202382A5086933278 @default.
• W2147202382 hasBestOaLocation W21472023821 @default.
• W2147202382 hasConcept C104317684 @default.
• W2147202382 hasConcept C126322002 @default.
• W2147202382 hasConcept C135763542 @default.
• W2147202382 hasConcept C140840227 @default.
• W2147202382 hasConcept C149151106 @default.
• W2147202382 hasConcept C1621761 @default.
• W2147202382 hasConcept C185592680 @default.
• W2147202382 hasConcept C2777477808 @default.
• W2147202382 hasConcept C2777628954 @default.
• W2147202382 hasConcept C2777849778 @default.
• W2147202382 hasConcept C31467283 @default.
• W2147202382 hasConcept C33664856 @default.
• W2147202382 hasConcept C526171541 @default.
• W2147202382 hasConcept C55493867 @default.
• W2147202382 hasConcept C62231903 @default.
• W2147202382 hasConcept C71924100 @default.
• W2147202382 hasConcept C98274493 @default.
• W2147202382 hasConceptScore W2147202382C104317684 @default.
• W2147202382 hasConceptScore W2147202382C126322002 @default.
• W2147202382 hasConceptScore W2147202382C135763542 @default.
• W2147202382 hasConceptScore W2147202382C140840227 @default.
• W2147202382 hasConceptScore W2147202382C149151106 @default.
• W2147202382 hasConceptScore W2147202382C1621761 @default.
• W2147202382 hasConceptScore W2147202382C185592680 @default.
• W2147202382 hasConceptScore W2147202382C2777477808 @default.
• W2147202382 hasConceptScore W2147202382C2777628954 @default.
• W2147202382 hasConceptScore W2147202382C2777849778 @default.
• W2147202382 hasConceptScore W2147202382C31467283 @default.
• W2147202382 hasConceptScore W2147202382C33664856 @default.
• W2147202382 hasConceptScore W2147202382C526171541 @default.
• W2147202382 hasConceptScore W2147202382C55493867 @default.
• W2147202382 hasConceptScore W2147202382C62231903 @default.
• W2147202382 hasConceptScore W2147202382C71924100 @default.
• W2147202382 hasConceptScore W2147202382C98274493 @default.
• W2147202382 hasIssue "4" @default.
• W2147202382 hasLocation W21472023821 @default.
• W2147202382 hasLocation W21472023822 @default.
• W2147202382 hasOpenAccess W2147202382 @default.
• W2147202382 hasPrimaryLocation W21472023821 @default.
• W2147202382 hasRelatedWork W1703321169 @default.
• W2147202382 hasRelatedWork W1999531606 @default.
• W2147202382 hasRelatedWork W2127833452 @default.
• W2147202382 hasRelatedWork W2147202382 @default.

• next