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• W2147203421 endingPage "18" @default.
• W2147203421 startingPage "1" @default.
• W2147203421 abstract "Zearalenone (ZEA) is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. It is frequently implicated in reproductive disorders of farm animals and occasionally in hyperoestrogenic syndromes in humans. There is evidence that ZEA and its metabolites possess oestrogenic activity in pigs, cattle and sheep. However, ZEA is of a relatively low acute toxicity after oral or interperitoneal administration in mice, rat and pig. The biotransformation for ZEA in animals involves the formation of two metabolites alpha-zearalenol (alpha-ZEA) and beta-zearalenol (beta-ZEA) which are subsequently conjugated with glucuronic acid. Moreover, ZEA has also been shown to be hepatotoxic, haematotoxic, immunotoxic and genotoxic. The exact mechanism of ZEA toxicity is not completely established. This paper gives an overview about the acute, subacute and chronic toxicity, reproductive and developmental toxicity, carcinogenicity, genotoxicity and immunotoxicity of ZEA and its metabolites. ZEA is commonly found on several foods and feeds in the temperate regions of Europe, Africa, Asia, America and Oceania. Recent data about the worldwide contamination of foods and feeds by ZEA are considered in this review. Due to economic losses engendered by ZEA and its impact on human and animal health, several strategies for detoxifying contaminated foods and feeds have been described in the literature including physical, chemical and biological process. Dietary intakes of ZEA were reported from few countries from the world. The mean dietary intakes for ZEA have been estimated at 20 ng/kgb.w./day for Canada, Denmark and Norway and at 30 ng/kgb.w./day for the USA. The Joint FAO/WHO Expert Committee on Food Additives (JECFA) established a provisional maximum tolerable daily intake (PMTDI) for ZEA of 0.5 microg/kg of body weight." @default.
• W2147203421 created "2016-06-24" @default.
• W2147203421 creator A5011563722 @default.
• W2147203421 creator A5045300418 @default.
• W2147203421 creator A5055965434 @default.
• W2147203421 creator A5076388241 @default.
• W2147203421 date "2007-01-01" @default.
• W2147203421 modified "2023-10-14" @default.
• W2147203421 title "Review on the toxicity, occurrence, metabolism, detoxification, regulations and intake of zearalenone: An oestrogenic mycotoxin" @default.
• W2147203421 cites W136948574 @default.
• W2147203421 cites W1499022677 @default.
• W2147203421 cites W1519335134 @default.
• W2147203421 cites W1533577926 @default.
• W2147203421 cites W1556508601 @default.
• W2147203421 cites W1561509515 @default.
• W2147203421 cites W1586106103 @default.
• W2147203421 cites W1606521510 @default.
• W2147203421 cites W1965134953 @default.
• W2147203421 cites W1966133724 @default.
• W2147203421 cites W1967013693 @default.
• W2147203421 cites W1967278686 @default.
• W2147203421 cites W1969361588 @default.
• W2147203421 cites W1969643309 @default.
• W2147203421 cites W1970500993 @default.
• W2147203421 cites W1970996500 @default.
• W2147203421 cites W1973986846 @default.
• W2147203421 cites W1975196307 @default.
• W2147203421 cites W1975985686 @default.
• W2147203421 cites W1977318809 @default.
• W2147203421 cites W1979436374 @default.
• W2147203421 cites W1980128160 @default.
• W2147203421 cites W1981351720 @default.
• W2147203421 cites W1981853391 @default.
• W2147203421 cites W1983279356 @default.
• W2147203421 cites W1984288657 @default.
• W2147203421 cites W1984739845 @default.
• W2147203421 cites W1984885499 @default.
• W2147203421 cites W1986797411 @default.
• W2147203421 cites W1988692727 @default.
• W2147203421 cites W1991466942 @default.
• W2147203421 cites W1991590342 @default.
• W2147203421 cites W1991940359 @default.
• W2147203421 cites W1993266259 @default.
• W2147203421 cites W1993464786 @default.
• W2147203421 cites W1995072556 @default.
• W2147203421 cites W1997380263 @default.
• W2147203421 cites W1997619156 @default.
• W2147203421 cites W1997816248 @default.
• W2147203421 cites W2000296812 @default.
• W2147203421 cites W2001843005 @default.
• W2147203421 cites W2002357195 @default.
• W2147203421 cites W2002493422 @default.
• W2147203421 cites W2002833978 @default.
• W2147203421 cites W2006992170 @default.
• W2147203421 cites W2012366476 @default.
• W2147203421 cites W2015358791 @default.
• W2147203421 cites W2016188743 @default.
• W2147203421 cites W2016221744 @default.
• W2147203421 cites W2017042190 @default.
• W2147203421 cites W2017112572 @default.
• W2147203421 cites W2020625939 @default.
• W2147203421 cites W2022487083 @default.
• W2147203421 cites W2022782050 @default.
• W2147203421 cites W2022786118 @default.
• W2147203421 cites W2022910554 @default.
• W2147203421 cites W2024572225 @default.
• W2147203421 cites W2024705626 @default.
• W2147203421 cites W2028125607 @default.
• W2147203421 cites W2028174284 @default.
• W2147203421 cites W2029062824 @default.
• W2147203421 cites W2029558673 @default.
• W2147203421 cites W2031850603 @default.
• W2147203421 cites W2032227606 @default.
• W2147203421 cites W2034420452 @default.
• W2147203421 cites W2036436529 @default.
• W2147203421 cites W2036994655 @default.
• W2147203421 cites W2037448330 @default.
• W2147203421 cites W2038880615 @default.
• W2147203421 cites W2038977640 @default.
• W2147203421 cites W2040718149 @default.
• W2147203421 cites W2042143505 @default.
• W2147203421 cites W2042599579 @default.
• W2147203421 cites W2042748727 @default.
• W2147203421 cites W2045374777 @default.
• W2147203421 cites W2046063671 @default.
• W2147203421 cites W2048883010 @default.
• W2147203421 cites W2050780317 @default.
• W2147203421 cites W2050836919 @default.
• W2147203421 cites W2055498874 @default.
• W2147203421 cites W2056794978 @default.
• W2147203421 cites W2057027252 @default.
• W2147203421 cites W2058604839 @default.
• W2147203421 cites W2058608292 @default.
• W2147203421 cites W2059159164 @default.
• W2147203421 cites W2059371483 @default.
• W2147203421 cites W2060899705 @default.
• W2147203421 cites W2062306267 @default.
• W2147203421 cites W2065092774 @default.

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