FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2147244558> ?p ?o ?g. }

• W2147244558 endingPage "1811" @default.
• W2147244558 startingPage "1806" @default.
• W2147244558 abstract "Objective. Hypertension (HTN), a common modifiable cardiovascular risk factor, is more common in patients with rheumatoid arthritis (RA), but the underlying mechanisms are unclear. We examined the hypothesis that mediators of inflammation and markers of cardiovascular risk are associated with HTN in RA. Methods. We compared measures of inflammation [serum C-reactive protein (CRP), tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), homocysteine, and leptin concentrations] and insulin resistance [homeostasis model assessment index (HOMA)] in RA patients with (n = 90) and without HTN (n = 79). HTN was defined as blood pressure ≥ 140/90 mm Hg or treatment with antihypertensive therapy. The independent association of markers of interest with HTN was examined using multivariable logistic regression. Results. Patients with HTN were significantly older and had longer disease duration than those without HTN (both p < 0.001). Concentrations of homocysteine [11.1 (8.5–13.5) μmol/l vs 9.3 (7.8–11.0) μmol/l] were significantly higher in patients with HTN (p < 0.001). After adjustment for age, sex, race, smoking, body mass index, and corticosteroid and nonsteroidal antiinflammatory drugs (NSAID) use, increased concentrations of homocysteine (OR 2.9, 95% CI: 1.5–5.5, p = 0.001), and leptin (OR 2.0, 95% CI: 1.0–3.8, p = 0.046) were significantly associated with HTN, but the 28-joint Disease Activity Score, IL-6, CRP, TNF-α, and HOMA index were not (all p > 0.05). Conclusion. HTN in patients with RA is not associated with generalized systemic inflammation or insulin resistance, but is associated with increasing concentrations of homocysteine and leptin. The pathogenesis of HTN in RA may involve pathways more regularly associated with fat and vascular homeostasis." @default.
• W2147244558 created "2016-06-24" @default.
• W2147244558 creator A5006402423 @default.
• W2147244558 creator A5016394865 @default.
• W2147244558 creator A5028596742 @default.
• W2147244558 creator A5028955607 @default.
• W2147244558 creator A5041824954 @default.
• W2147244558 creator A5049299671 @default.
• W2147244558 creator A5070999679 @default.
• W2147244558 creator A5082867664 @default.
• W2147244558 date "2013-09-01" @default.
• W2147244558 modified "2023-09-24" @default.
• W2147244558 title "Inflammation and Hypertension in Rheumatoid Arthritis" @default.
• W2147244558 cites W1540368657 @default.
• W2147244558 cites W1970405926 @default.
• W2147244558 cites W1975702264 @default.
• W2147244558 cites W1977357923 @default.
• W2147244558 cites W1980844526 @default.
• W2147244558 cites W1982016257 @default.
• W2147244558 cites W1992255543 @default.
• W2147244558 cites W1992808043 @default.
• W2147244558 cites W2014793094 @default.
• W2147244558 cites W2017281076 @default.
• W2147244558 cites W2024177221 @default.
• W2147244558 cites W2033132851 @default.
• W2147244558 cites W2034674656 @default.
• W2147244558 cites W2035934024 @default.
• W2147244558 cites W2037264171 @default.
• W2147244558 cites W2042717201 @default.
• W2147244558 cites W2051424872 @default.
• W2147244558 cites W2051540382 @default.
• W2147244558 cites W2054004405 @default.
• W2147244558 cites W2059748176 @default.
• W2147244558 cites W2064729662 @default.
• W2147244558 cites W2067316789 @default.
• W2147244558 cites W2068421711 @default.
• W2147244558 cites W2089483637 @default.
• W2147244558 cites W2103777208 @default.
• W2147244558 cites W2110177517 @default.
• W2147244558 cites W2112827359 @default.
• W2147244558 cites W2121262506 @default.
• W2147244558 cites W2127149147 @default.
• W2147244558 cites W2134693680 @default.
• W2147244558 cites W2138510167 @default.
• W2147244558 cites W2140655158 @default.
• W2147244558 cites W2142177680 @default.
• W2147244558 cites W2147811682 @default.
• W2147244558 cites W2151279508 @default.
• W2147244558 cites W2152348310 @default.
• W2147244558 cites W2160234571 @default.
• W2147244558 cites W2323783182 @default.
• W2147244558 cites W2335398010 @default.
• W2147244558 doi "https://doi.org/10.3899/jrheum.130394" @default.
• W2147244558 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3818311" @default.
• W2147244558 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23996293" @default.
• W2147244558 hasPublicationYear "2013" @default.
• W2147244558 type Work @default.
• W2147244558 sameAs 2147244558 @default.
• W2147244558 citedByCount "28" @default.
• W2147244558 countsByYear W21472445582014 @default.
• W2147244558 countsByYear W21472445582015 @default.
• W2147244558 countsByYear W21472445582016 @default.
• W2147244558 countsByYear W21472445582017 @default.
• W2147244558 countsByYear W21472445582018 @default.
• W2147244558 countsByYear W21472445582019 @default.
• W2147244558 countsByYear W21472445582020 @default.
• W2147244558 countsByYear W21472445582021 @default.
• W2147244558 countsByYear W21472445582022 @default.
• W2147244558 crossrefType "journal-article" @default.
• W2147244558 hasAuthorship W2147244558A5006402423 @default.
• W2147244558 hasAuthorship W2147244558A5016394865 @default.
• W2147244558 hasAuthorship W2147244558A5028596742 @default.
• W2147244558 hasAuthorship W2147244558A5028955607 @default.
• W2147244558 hasAuthorship W2147244558A5041824954 @default.
• W2147244558 hasAuthorship W2147244558A5049299671 @default.
• W2147244558 hasAuthorship W2147244558A5070999679 @default.
• W2147244558 hasAuthorship W2147244558A5082867664 @default.
• W2147244558 hasBestOaLocation W21472445581 @default.
• W2147244558 hasConcept C126322002 @default.
• W2147244558 hasConcept C134018914 @default.
• W2147244558 hasConcept C151956035 @default.
• W2147244558 hasConcept C2776914184 @default.
• W2147244558 hasConcept C2777090595 @default.
• W2147244558 hasConcept C2777575956 @default.
• W2147244558 hasConcept C2780221984 @default.
• W2147244558 hasConcept C2780613262 @default.
• W2147244558 hasConcept C2781195455 @default.
• W2147244558 hasConcept C50440223 @default.
• W2147244558 hasConcept C511355011 @default.
• W2147244558 hasConcept C555293320 @default.
• W2147244558 hasConcept C71924100 @default.
• W2147244558 hasConcept C84393581 @default.
• W2147244558 hasConcept C90924648 @default.
• W2147244558 hasConceptScore W2147244558C126322002 @default.
• W2147244558 hasConceptScore W2147244558C134018914 @default.
• W2147244558 hasConceptScore W2147244558C151956035 @default.
• W2147244558 hasConceptScore W2147244558C2776914184 @default.
• W2147244558 hasConceptScore W2147244558C2777090595 @default.

• next