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- W2147355857 abstract "Case Presentation The patient was an 84-year-old man with the recent onset of fatigue, shortness of breath, night sweats, and easy bruising, and weight loss of 10 pounds during the past 6 months. Physical examination revealed posterior cervical, axillary, and inguinal lymphadenopathy and questionable splenomegaly. After review of his admission peripheral blood smear, the medical technologist immediately brought the smear to the attention of the pathologist. Pathology review of the peripheral blood (Image 1A-D and Table 1) showed presence of a leukocytosis with numerous blast/immature cells. The attending physician was immediately contacted and the specimen was then submitted for flow cytometry. These blast/immature cells were described as intermediate to large sized, possessing generally oval nuclei, with scattered numbers of these nuclei with smooth though irregular contours. The nuclear chromatin tended to be evenly distributed, with both a granular and reticular appearance. The degree to which the nuclear chromatin had a condensed and smudged appearance varied from cell to cell. In scattered numbers of these nuclei there were indistinct nucleoli, whereas in other nuclei there were more prominent nucleoli, primarily single, though in some nuclei they were multiple. The nuclear/cytoplasmic ratio was variable, ranging from moderate to high, and the cytoplasm lacked differentiation, showing fairly deep basophilia. There were occasional scattered cells, small to intermediate in size," @default.
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- W2147355857 date "2005-03-01" @default.
- W2147355857 modified "2023-10-03" @default.
- W2147355857 title "Mantle Cell Leukemia, Blastoid Variant" @default.
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