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- W2147367000 abstract "The antihypotensive effect of amezinium metilsulfate, a newly developed antihypotensive agent, and the drug's effect on norepinephrine, epinephrine, and atrial natriuretic peptide was investigated in nine hemodialysis patients with hypotension. Amezinium metilsulfate 10 mg once daily was administered on the day of hemodialysis for a period of 12 weeks. After treatment with amezinium, both systolic and diastolic blood pressures at 3, 4, and 5 hours after hemodialysis were significantly higher than those during a control period. The infusion volume during hemodialysis was significantly decreased with the treatment. Plasma norepinephrine, epinephrine, and atrial natriuretic peptide levels were not significantly different after therapy compared with the control period. These results confirm that amezinium metilsulfate is a safe and effective antihypotensive agent for the treatment of hypotension associated with hemodialysis." @default.
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- W2147367000 date "1993-04-01" @default.
- W2147367000 modified "2023-10-15" @default.
- W2147367000 title "Antihypotensive and hormonal effects of amezinium metilsulfate in hypotensive hemodialysis patients" @default.
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- W2147367000 doi "https://doi.org/10.1016/s0011-393x(05)80196-1" @default.
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